... advantage and safety profile of the management approaches employed in patien ts with primary colonic melanoma. Based on a synthesis of the current data, it appears that the management of primary Khalid ... ms at the time of diagnosis of colonic melanoma. In addition, Figure 1 Comparison of anatomic distribution in primary and metastatic melanoma of colon. Khalid et al. World...
Ngày tải lên: 09/08/2014, 01:24
... cyclophosphamide 250 mg/m 2 on days 2–4 of cycle 1 and days 1–3 of cycles 2–6 , and rituximab 375 mg/m 2 on day 1 of cycle 1 and 500 mg/ m 2 on day 1 of cycle 2–6 , every 28 days for 6. OR was 94%, CR ... complement fixation are under clinical investiga- tion. Of this new generation of anti-CD20 antibodies, ofatumumab has generated the most mature clinical data. Ofa...
Ngày tải lên: 10/08/2014, 22:20
báo cáo khoa học: "The occurrence and management of fluid retention associated with TKI therapy in CML, with a focus on dasatinib" pptx
... Goldman JM: International randomized study of interferon versus STI571 (IRIS) 7-year follow-up: sustained survival, low rate of transformation and increased rate of major molecular response (MMR) in ... no direct comparisons of efficacy of nilotinib and dasatinib in CML. Although both second-line TKIs are well tolerated, side effects do occur during treatment. Management of...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo khoa học: "Housing, Feeding and Management of Calves and Replacement Heifers in Swedish Dairy Herds" doc
... levels of serum pepsinogen in calves on organic farms using different methods of grazing management to control parasite infections. Well nourished hosts can better withstand the effect of parasites and ... transfer of colostral im- munoglobulins to calves. Proc. Xth Conf. of Am. Ass. of Bovine Pract. Pittsburgh, USA, 1994, 500-504. Goodger WJ, Theodore EM: Calf management pr...
Ngày tải lên: 12/08/2014, 15:20
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... HPRT A B C D PRTFDC1 PRTFDC1 HPRT HPRT 0.4 0.3 V (µmol·min –1 ·mg –1 ) V (µmol·min –1 ·mg –1 ) V (µmol·min –1 ·mg –1 ) V (µmol·min –1 ·mg –1 ) 0.2 0.1 0.0 0 50 100 150 –5 0 200 400 600 800 1000 0 50 100150 200 250 S –5 0 0 2 4 6 8 10 12 50 ... Lesch–Nyhan syndrome, a disease with symptoms of self mutilation and mental retardation [4]. The underlying mec...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Covalent binding to glutathione of the DNA-alkylating antitumor agent, S23906-1 doc
... presence of increasing concentrations of GSH (d)or GSSG (h). The fluorescence of the drug–DNA complexes in the controls (without GSH or GSSG) was considered to be 100%. Fig. 5. Competitive binding of ... the type of adducts formed and their biological effects often vary significantly Fig. 10. Effect of buthionine sulfoximine (BSO) on the cytotoxicity of S23906-1 and the formation...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: "Tagging Inflective Languages: Prediction of Morphological Categories for a Rich, Structured Tagset" docx
... mean that all combinations of values of two (or more) categories are systematically possible, i.e. that every member of the cartesian product of the two (or more) sets of values do appear in the ... certain number of times. Using ambiguity classes instead of unique values of morphological categories for evaluating the (con- text part of the) features has the advantage o...
Ngày tải lên: 17/03/2014, 07:20
Báo cáo khoa học: Substrate recognition and ®delity of strand joining by an archaeal DNA ligase docx
... the effect of single base mismatches at the nick of DNA substrates on the ligation reaction. In the case of 3¢ mismatched substrates (Fig. 5A), Lig Tk ef®ciently ligated Fig. 4. Length of oligonucleotides ... the enzyme results in release of PPi or NMN from the cofactor and formation of enzyme±adenylate through t he covalent addition of AMP to the conserved AMP-binding site lysi...
Ngày tải lên: 17/03/2014, 11:20
Báo cáo khoa học: "Beyond Projectivity: Multilingual Evaluation of Constraints and Measures on Non-Projective Structures" doc
... maximum over gap degrees of all subtrees of a dependency tree (the gap degree of a subtree is the number of contiguous intervals in the gap of the subtree). The interval degree of an edge is bounded ... component rooted in an ancestor of the edge (an ancestor of an edge is any node on the path from the root of the whole tree to the parent node of the edge). The proportions...
Ngày tải lên: 23/03/2014, 18:20
Báo cáo khoa học: "Grammar Writing System(GRADE) of Mu-Machtne Translation Project and its Characteristic" docx
... year as the software of the nattonal machtne translation project from Japanese Into English. The effectiveness of GRADE has been demonstrated tn thts project. The linguistic parts of the project ... 2 shows an example of the application of a maln part. 4. Control of the grammatical rule applications A grammar writing language must be able to express detailed phases of...
Ngày tải lên: 24/03/2014, 01:21