Báo cáo y học: "The PIRO Concept: O is for organ dysfunction" pot

... Increasingly, the endocrine system is one of those systems, so I don’t really know what the outcome measure would be. One of the curious things you find when you do that is any one you look at is no longer ... when you use statistical analysis, and at this stage we’re still trying to generate information – we don’t really know where the cut point is. Meeting report The PIRO Concept...

Ngày tải lên: 12/08/2014, 19:22

... search I performed for the terms “gene AND polymorphism AND atherosclerosis OR vascular biology OR thrombosis OR lipoprotein” turned out to have more than 3000 original publications. However, when ... of PIRO, which is thinking about severe septic patients across four domains. P for ‘predisposition’, predisposing factors that would make Meeting report The PIRO concept: P is for...

Ngày tải lên: 12/08/2014, 19:22

... as to whether you think this organism is simply colonizing or whether it is causing a real infection. So you could imagine you might say ‘I0’ is colonization, ‘I1’ is local infection, ‘I2’ is ... of this would be that you could say, ‘I’ will be L for Lung, U for microorganism unknown on day 1, and next day it is L ‘pseud’ or whatever the code is for Pseudomonas plus/minus...

Ngày tải lên: 12/08/2014, 19:22

... important to say that PIRO is really meant as a hypothesis-generating model. None of us are introducing it with the idea that tomorrow we’ll go look at a patient and work out their PIRO score. Really ... therapy, or to have prognostic information? That’s why we should not only talk about appropriate markers for the response but also discuss the cause of the response. What we all know...

Ngày tải lên: 12/08/2014, 19:22

... ALI. Identifying conditions that have an effect on the propensity to develop organ dysfunction in sepsis will allow for the expan- sion of studies on interventions for this disease. Further pro- spective ... necessary to identify a possible mechanism for affecting the development of ALI. Conclusions This study confirms previous observations that a history of DM is associated with a...

Ngày tải lên: 13/08/2014, 15:21

... to a query molecule through a distance-based approach. Visualizing systems biology A common theme in contributions on systems biology was the integration of various data sources for visualizing, inferring ... graph- theoretical discovery method for long and highly similar motifs 301.2 Genome Biology 2007, Volume 8, Issue 1, Article 301 Sahinalp http://genomebiology.com/2007/8/1/301 Genome...

Ngày tải lên: 14/08/2014, 17:22

... to their Galaxy Project. e ambitious goal of Galaxy is to empower regular users to carry out their own computational analysis without having to be an expert in computational biology or computer ... and the project is not without limitations, but it is now the leading platform for computational analysis of DNA sequence data. e standard installation is loaded with analysis too...

Ngày tải lên: 09/08/2014, 20:22

... 99.9% accuracy for Homozygote Refer- ence (HomRef), 97.0% for he terozygote (Het), and 92.3% for Homozygote NonReference (HomNonRef). The overall false discovery rate of variant genotypes was <3% ... p o p ulations Number of variants Benign, Exon + Low Coverage Pilots Benign, Exon Pilot only Possibly damaging, Exon + Low Coverage Pilots Possibly damaging, Exon Pilot only Damaging,...

Ngày tải lên: 09/08/2014, 23:20

... forms of cannabis are morphologically variable, resulting in confusion and controversy over the taxonomic organization of the genus (see [8] for review). Some authors have proposed a monotypic ... cannabigerolic acid; CMK, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; CTAB, cetyl trimethylammonium bromide; DXR, 1-deoxy-D-xylulose 5- phosphate reductoisomerase; DXS, 1-deoxyxylulose-5...

Ngày tải lên: 09/08/2014, 23:20

... one organized by the Achaeans the presence of doc- tors would have been more than necessary. Indeed, two of Asklepios’ sons, Mahaon and Podaleirios, are referred to by the poet as doctors who ... of it there is another reference to Mahaon’sinjuryaswellastothatofhisbrother,Poda- leirios. Eurypylos is injured in his thigh with an arrow and he begs Patroclus to bring him into his tent so ......

Ngày tải lên: 10/08/2014, 09:22