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Báo cáo y học: " Interactions between the increase in venous return and right ventricular functio" potx

Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

... orientation, and specificity of thisdomain, with residues Tyr91 and Tyr137 forminginteraction pocket 1; Tyr93, Tyr137 and Trp119 form-ing pocket 2, and the valley between n-Src and RTloops included by ... into binding grooves 1 and 2 created by the n-Srcloop and the 310helix, stabilized by stacking interac-tions of the pyrrolidine ring of Pro7 with the aromaticside chain of Tyr137. Modelling ... thus, the interaction is highly dependenton phosphorylation performed by the Src family kinase Fyn, which docksonto PAG using a dual-domain binding mode involving both SH3- and SH2-domains of Fyn....
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Báo cáo y học: " Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice" pptx

... purposes)Rapamycin reverses hypoxia-induced thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 6Rapamycin reverses hypoxia-induced thickening of the right ventricular ... cardiomyo-cytes of the left ventricular wall were unaffected bychanges in the oxygen supply. Hypoxia-induced hypertro-phy of the right ventricle and of individual right ventricu-lar cardiomyocytes ... purposes)Rapamycin attenuates hypoxia-triggered thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 4Rapamycin attenuates hypoxia-triggered thickening of the right...
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Báo cáo y học: "Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases" ppt

... feedbacksystem between TNFα and IL-32 promotes the tissue inflam-mation in the synovium and the intestinal epithelium. In thisway, IL-32 has a close relationship with the proinflammatorycytokines, ... detected in the synovial-infiltratedlymphocytes. We supposed that IL-32-producing lym-phocytes infiltrating the inflamed synovium participate in the production of TNFα in the RA synovium.This ... the transduced cytokine only in bone-marrow-derived cells, not in fibroblasts or chondrocytes of the joints. There would there-fore be no initiation of inflammation in the joints without the infiltration...
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Báo cáo khoa học: " Interactions between Scots pine, Ips acuminatus (Gyll.) and Ophiostoma brunneo-ciliatum (Math.): estimation of the critical thresholds of attack and inoculation densities and effects on hydraulic properties in the stem" pdf

... occurs late in the infection cycle, and playsprobably only a minor role in the potential success ofinsect installation. The latter is probably strongly relyingon the dynamic balance between rapid ... largely from that induced by woundingalone. The latter resulted mainly in a very limited sap-wood drying very close to the wounds and almost noresinosis. The presence of the fungus resulted in ... in heavyresinosis, sapwood drying and in one case, blue staining.Figure 5. Relationship between visually assessed damage in the sapwood, and the measured loss of hydraulic conductivity, in stem...
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Báo cáo y học: "Association between the TNFRII 196R allele and diagnosis of rheumatoid arthritis" potx

... populations and/ or genetic markers. The latterhave the particular advantages of being present from the onsetof the disease and of remaining unchanged by therapy. Todate, the only genetic susceptibility ... early inflamma-tory arthritis who were prospectively recruited between Octo-ber 1998 and January 2002 in two French regions: the entireprovince of Upper Normandy (1,800,000 people) and the ... after receiving verbal and written information regard-ing the nature, duration and purpose of the study. The protocolwas approved by the Committee for Protection of PersonsParticipating in Biomedical...
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Báo cáo y học: "Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case–control study" docx

... confer their activation of the immune system mainly in the lymph nodes, without leaving any signs of inflammation in the exposed skin [11,25-28]. Here, an initial activation of the innate immune system ... previously [16], all potential cases were examined and diagnosed by a rheumatologist at the unit entering the case into the study. All rheumatology units linked to the gen-eral welfare system in the ... beings, would trigger the activation of a cascade ofevents involving activated T lymphocytes, and that theseevents for as yet unknown reasons finally result in inflammatoryjoint disease. In...
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Báo cáo y học: " Relationships between the Foot Posture Index and foot kinematics during gait in indivi" pdf

... association between the FPI and some parameters of dynamic foot function. Inconsistent findings between the PFPS and control groupsindicate that pathology may play a role in the relationship between ... group.Inconsistent findings between the PFPS and controlgroupsindicatethatpathologymayplayaroleintherelationship between static foot posture and dynamicfunctio n. The association between ... participants without definedpathology. Although the effect of pathology on kine-matics may explain equivocal findings between Chuter’s[12] study and the PFPS group in the current study,such an effect...
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Báo cáo y học: "Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis" doc

... explanation for the discrepancy between the in vitro and in vivo settings might be that the intravenously injected MSCs do not reach the spleen and ly mph nodes and are therefore unable to inhibit the Figure ... immunized on day 0 with collagen type II (CII) in complete Freund’s adjuvant and injected intravenously with MSCs on day 16 and day 23. The mean arthritic score (a) and the cumulativeincidence of ... 5-ethynyl-2’ -deoxyuridine (EdU) in the T-cell populations in the spleen and lymph nodes by fluorescence-activated cell sorting analysis. The percentages of EdU-positive cells in the CD4+ and CD8+populations...
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Báo cáo y học: "Association between the PTPN22 +1858 C/T polymorphism and psoriatic arthritis" docx

... designed the investigation, and participated in the data collection, statistical analysis and drafting of the manuscript.Competing interests The authors declare that they have no competing interests.Received: ... with the present study. The patient:control ratio in our study is 291:725, in the UK cohort455:595 [14], in the German patient group 375:299 [15], in the Newfoundland cohort 238:149 and in the ... regression analysis (P = 0.017). There was noassociation between dactylitis and deformed joints and, no other significant associations between the ca rriage of the risk allele, T, and other examined disease...
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