Báo cáo y học: "Erythropoietin mimics the acute phase response in critical illnes" pdf
Báo cáo y học: "Erythropoietin mimics the acute phase response in critical illnes" pdf
... distinguished from noncritically ill patients with varying haemoglobin concentrations. Exogenous EPO therapy is unlikely to be effective in the first few days of critical illness. Keywords acute ... subsequently died, paralleling changes in the acute phase response [17]. If exogenous EPO therapy is to have a cost-effective role in the treatment of the anaemia of criti...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: " Trauma and the acute care surgery model – should it embrace or replace general surgery?" pps
... However, this is still heavily debated in the US [36-39]. Many practicing surgeons will say that they are already doing Acute Care Surgery – and by many means they probably are correct – e.g. appendicitis, ... tailored according to the need of any region. Refurnishing the training in General Surgery may embrace the concepts built into the Acute Care Surgery model and ensure...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... subfamily of the cytoch- rome P450 (CYP) enzymatic system, is responsible for the metabolism of tacrolimus [10]. Specifically; tacro- limus is mainly metabolized by CYP3A4 and CYP3A5 enzyme isotype. ... important CYP3A5 polymorphism. The alleles A and G are CYP3A5*1 and CYP3A5*3, respectively. Indi- viduals carrying at least one CYP3A5*1 allele express CYP3A5 protein whereas individ...
Ngày tải lên: 26/10/2012, 09:32
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... detected by silver staining on polyacrylamid gel. Statistical Analysis Allele frequencies were determined by gene counting and compared using the א² test. The data was analysed using SPSS ... altered which may influence the effect of PPARδ on metabolism. In our data and in the study by Skogsberg et al., the effect of the C allele on lipid levels increased if over-weigh...
Ngày tải lên: 31/10/2012, 17:03
Tài liệu Báo cáo Y học: Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity docx
... decrease in the activity for the 11b-hydroxylase, CYP11B1. Intriguingly, however, the 11b-hydroxylase activity of the aldosterone synthase CYP11B2 was basically unaffected whereas the 18-hydroxy- lation ... to adrenodoxin when compared with CYP11B2. CYP11B1 has a tryptophan at position 366 while all other proteins of the CYP11B family including CYP11B2 of the guinea pig have a...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo y học: "Giantin is the major Golgi autoantigen in human anti-Golgi complex sera" pptx
... has a prominent function in the processing, transport- ing, and sorting of intracellular proteins subsequent to their synthesis in the rough endoplasmic reticulum. Struc- turally, the Golgi complex ... 1–3259), with the exception of the 38 amino acids at the amino-terminus (Fig. 3). Forty sera containing antigiantin antibody were analyzed using ELISA (Fig. 4, Table 3). Based o...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf
... grading system are presented in Figure 1. Quantification of inflammatory cytokines in synovial fluid Cytokine profiles in synovial fluid were determined using a BD™ cytometric bead array (BD ... to inhibition by URB597 (3'-(aminocarbonyl) [1,1'-biphenyl]-3-yl)- cyclohexylcarbamate). Conclusion Our data predict that the cannabinoid receptor system present in the synovium...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " Reduction of the HIV-1 reservoir in resting CD4+ T-lymphocytes by high dosage intravenous immunoglobulin treatment: a proof-of-concept study" pot
... copies/mL ³ 1.5 years, were included in the study. Written informed consent was obtained and the study was approved by the Research Eth- ics Committee at the University of Gothenburg and the Medical ... overnight at 37°C in a 5% CO 2 incubator to remove monocytes by adherence. The fol- lowing day the monocytes-depleted PBMCs were further purified using a Dynal CD4 Negative I...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Inflammatory responses to acute pneumovirus infection in neonatal mice" pps
... of inflammation. Conclusions: Our findings among the youngest mice may explain in part the phenomenon of atypical or minimally symptomatic respiratory infections in human neonates, which may be ... promoting protection and in vaccination strategies [18-22]. Interestingly, as the mice used in th is study were born to immunologically naïve mot hers, the differences in inflamma...
Ngày tải lên: 12/08/2014, 02:20
Báo cáo y học: " Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using modelbased approaches" ppt
... figure shows that the intra- and inter- study variability in mean trough FEV 1 may be as high as 50 mL, whereas the inter-study variability in median response may be about 60 mL. The implications ... [7]. While the conventional approach originally selected the 150 and 300 μg d oses, uncertainty remained about their location on the dose response and, in particular, the...
Ngày tải lên: 12/08/2014, 13:22