Báo cáo y học: "Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis" pot
Báo cáo y học: "Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis" pot
... on the observation that the concentration of drotrecogin alfa (activated) in plasma is below the assay level of detection in a large majority of patients within 2 hours of discontinuing the infusion ... safety profile in 1690 patients studied in the F1K-MC-EVAD (PROWESS) trial. We analyzed all available data on the safety of treatment with drotre...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: "Spinal manipulative therapy versus Graston Technique in the treatment of non-specific thoracic spine pain: Design of a randomised controlled trial" potx
... old with a primary complaint of thoracic pain (Figure 1: Mannequin defining the area of thoracic pain) and with no contraindications to manual therapy or Graston Technique. Upon making an appointment ... the person requesting the randomisation has confirmed that they wish to proceed with entry into the trial. The participants will be analysed in the groups to which the...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo y học: "Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis" pdf
... have identified an increase in proteolytic activity within the glomerulus coinciding with the development of proteinuria in the (NXB×NZW)F 1 mouse model of systemic lupus erythematosus. Here we ... with evidence of central nervous system involvement. There are reports indicating a central role for MMPs in increasing permeability of the blood-brain barrier in inflam...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Low-concentration, continuous brachial plexus block in the management of Purple Glove Syndrome: a case report" pps
... vein resulting in disruption of the endothelial-intercellular junctions and seepage of the drug into the interstitial space [1]. Extravasation of the highly albumin-bound (70- 90%) phenytoin increases the ... the advantage of blocking the sympathetic innervation of the upper limb, thus improving the perfusion and relieving the ischaemic pain associated with v...
Ngày tải lên: 11/08/2014, 11:22
Báo cáo y học: " HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic interventio" ppsx
... quantities of Vpr. 2). Vpr promotes the binding of the PIC (including MA, integrase (IN) and proviral DNA) to importins and nucleoporins, thereby facilitating nuclear entry of HIV-1 provirus into the ... found in brains of patients suffering from HIV-D [155]. The presence of TNF-a protein and mRNA in patients with HIV-D has been reported to sig- nificantly correlat...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: "Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomised controlled trial" pdf
... by 1 cmH 2 O every four respiratory cycles, if the patient's RR was less than 15 per minute). The primary endpoint of the study was the duration of the weaning process. Secondary endpoints ... haemody- namic instability (five patients) , one refusal to continue in the study and nine complications were related to the ventilator and the automatic mode of weaning....
Ngày tải lên: 13/08/2014, 11:23
Báo cáo y học: "Is smaller high enough? Another piece in the puzzle of stress, strain, size, and systems" pdf
... areas, indicating sustained derecruitment of the lungs. This phenomenon has also been demonstrated in the clinical setting by Richard and colleagues [7] in ARDS patients while reducing the tidal ... the concept of setting PEEP according to a table becomes evident, and in the present study, what is very probably a ‘false’ PEEP reduction (obviously triggered by the incre...
Ngày tải lên: 13/08/2014, 15:22
Báo cáo y học: " Safety assessment of inhaled xylitol in mice and healthy volunteers" ppsx
... can enhance innate immunity by increasing the potency of the natural antimicrobial peptides. In addition to increasing the activity of individual ASL factors, lowering the NaCl concentration also independently ... covered by a thin layer of liquid (airway surface liquid [ASL]) that contains many antimi- crobial substances including lysozyme, lactoferrin, human β defensins, and...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"
... reporting on the use of EHA com- bined with autologous bone but without the applica- tion of a membrane in the treatment of infra bone de- fects, our clinical results are encouraging considering ... promote healing [fig. 7-8]. After surgery, patients were instructed to rinse their mouths twice daily with 10 ml of 0.2 % chlorexidine for 6 weeks. RESULTS The man...
Ngày tải lên: 03/11/2012, 11:35
Báo cáo Y học: A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus doc
... Gly23 of birtoxin (Fig. 4). In ikitoxin the presence of Glu23 charge preceding the a-helix modifies the activity of this toxin in a unique way to result in reduced potency in mice. The C-termini of ... which the symptoms faded and the mice completely recovered. Ikitoxin did not show lethality during the course of the observation period in the range of in...
Ngày tải lên: 31/03/2014, 08:20