... inflammatory infiltration are present in the dermis. (A) Hema- toxylin and eosin staining, 100× magnification. (B) Hematoxylin and eosin staining, 40× magnification. Teran et al. Journal of Medical ... obtained from the patient's next -of- kin for publication of this case report and any accompanying images. A copy of the written con- sent is available for review by...
Ngày tải lên: 11/08/2014, 12:20
Báo cáo y học: "Understanding the roles of the transcription factors nuclear κ α factor-κB and hypoxia-inducible factor-1α in lung injury" pptx
... strategies. In his review John Haddad describes the present data and role for transcription factors nuclear factor-κB and hypoxia-inducible factor- 1α in acute lung injury. Keywords hypoxia, hypoxia-inducible ... on the contributions of transcription factors to lung injury. The topic is large and ever changing, and the complete coverage of nuclear...
Ngày tải lên: 12/08/2014, 19:21
... mesenchymal benign lesions origi- nating from the mature lipid tissue 1 . They constitute approximately 0.6% of the laryngeal and hypopha- ryngeal benign tumors 4 . Laryngeal and hypopharyn- geal ... correspond- ing to the laryngeal vestibule level in sagittal section, projecting towards the inferior from the arytenoid cartilage level. It appeared hypointense in T1-wei...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Two-year Outcome of Turkish Patients Treated with Zotarolimus Versus Paclitaxel Eluting Stents in an Unselected Population with Coronary Artery Disease in the Real World: A Prospective Non-randomized Registry in Southern Turk
... angio- graphic rather than clinical end points, clinical trials comparing the safety and efficacy between these DES types and BMSs have yielded inconsistent results. In the ENDEAVOR I, II,II Continued ... prematurely taken off their antiplatelet therapy and this likely played a role in the observed MACE events. Also noteworthy was the observation that, the lesion and...
Ngày tải lên: 25/10/2012, 11:18
Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx
... 36% of the interaction of the full peptide with the binding cavity of SM3. The sizes of the surfaces were determined using distances between ligand atoms and protein atoms of less than 3 A ˚ . These ... struc- ture into the binding cavity of SM3 and the binding epitope obtained from STD NMR is very good. Comparison with the X-ray and previous NMR structures A...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... catalyzes the synthesis of CTP from UTP by amination of the pyrimidine ring at the 4-position. The enzyme has three functionally distinct sites; the glutaminase site where glutamine hydrolysis ... synthase is suggested. Here the binding of GTP to the allosteric site promotes coordination of the phosphorylation of UTP and hydrolysis of glutamine for optimal efficien...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Osmoregulated periplasmic glucans of the free-living photosynthetic bacterium Rhodobacter sphaeroides doc
... form); (b) they are linked by b-1,2 linkages and one a-1,6 linkage; and (c) they are highly substituted by succinyl and acetyl residues. They also exhibit some degree of structural rigidity as demonstrated ... genes of the csubdivision [1]. In a companion paper [23], we demonstrate that the genes governing the synthesis of cyclic OPGs in R. sphaeroides are related to tho...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
... epitopes of gp130 are involved in ligand binding: the Ig-like domain and the CBM [9–11]. In the case of LIF-induced heterodimerization of LIFR with gp130, the cytokine first binds to the Ig-like domain ... positioned by the disulfide bond between cysteines C458 and C466 [30]. To analyse the role of the three cysteines in D5 of gp130 in heterodimerization wi...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: Chimeric receptor analyses of the interactions of the ectodomains of ErbB-1 with epidermal growth factor and of those of ErbB-4 with neuregulin potx
... N- and C-terminal parts of the ligand are cross-linked to domains I and III, respectively, of the receptor [19,22]. The b sheet of EGF may bind to domain I of ErbB-1, and the other surface of the ... to the EGF receptor. A deletion in the N-terminal region of domain I impaired the EGF binding of ErbB-1 [21]. The N-terminus of EGF was linked to Tyr101...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes pdf
... fluorescence properties of the W48 and W56 residues, either in combi- nation in the WT-penetratin, or separately in the W48F- and the W56F-penetratin single variants, and the effect of incorporating negatively charged ... scattering was carried out by subtracting the corres- ponding spectra of the SUVs. Peptide–lipid binding was determined from the quenching...
Ngày tải lên: 31/03/2014, 23:20