Báo cáo y học: "Effects of cigarette smoke on degranulation and NO production by mast cells and epithelial cells" pot

... situation. The major findings of this study were that CSS inhibited mast cell degranulation, production of NO by mast cells and tracheobronchial epithelial cells, as well as expression of the ... NO and the mechanism for this reduction was therefore studied in in vitro models of airway epithelial cells and mast cells. The effects of cigarette smoke...

Ngày tải lên: 12/08/2014, 18:22

... in rings of pulmonary artery and aorta as the relaxation induced by ADP. The proliferation of smooth muscle cells and their phenotype in small pulmonary vessels were evaluated by immunohistochemical ... smoking may contribute to pulmonary hypertension in chronic obstructive pulmonary disease by altering the structure and function of pulmonary vessels at early disease stage...

Ngày tải lên: 12/08/2014, 14:20

... proliferation and survival, was increased by various concentrations of CSC, and sustained up to 24 h only at mitogenic concentrations of CSC (1 AU/ml). Higher, cytotoxic concentrations of CSC resulted in ... curve, and expressed as nmol/mg Effect of CSC and its modulation by BSO and NAC on cell proliferation in NCI-H292Figure 1 Effect of CSC and its modulation by...

Ngày tải lên: 12/08/2014, 18:20

... group B (one-way ANOVA). Control: healthy rabbit myocardium, Group A: non-ischemia- reperfusion group of hypertrophied myocardium, Group B: ischemia- reperfusion group of hypertrophied myocardium, ... hypertrophied myocardium by up- regulating the expression of Cx43. Keywords: Cardioelectrial activity Connexin43, Ischemic preconditioning, Myocardial hypertrophy Background Various degr...

Ngày tải lên: 10/08/2014, 09:21

... infusion of prostacyclin (epoproste- nol) on echocardiographic measures of right ventricular struc- ture and function in primary pulmonary hypertension. Primary Pulmonary Hypertension Study Group. ... hypoxia- induced pulmonary hypertension, and healthy animals with and without blockade of the autonomic nervous system. Results During pulmonary hypertension, inhalation of ilopr...

Ngày tải lên: 13/08/2014, 11:22

... accumula- tion of inflammatory cells in BAL and lung. Sole SEB application on the other hand resulted in raised levels of KC, IFN-g andIL-17A,butnotMCP-1.Interestingly, the combined exposure of smoke and ... risk of bacterial colonization and respiratory tract infection, because of suppressed antibacterial activities of the immune system and delayed clearance of mi...

Ngày tải lên: 12/08/2014, 13:22

... condensate; CSC) and examined for the production of proinflammatory cytokines and activation of MAPK and NF κB. The results demonstrate that the acute phase response of pulmonary epithelial cells ... article Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells Gary R Hellermann, Szilvia B Nagy, Xiaoyuan Ko...

Ngày tải lên: 12/08/2014, 18:20

... Effects of polysulfated glycosaminoglycan and hyaluronan on prostaglandin E 2 production by cultured equine synoviocytes. Am J Vet Res 2000, 61:499-505. 29. Lee EK, Kang SM, Paik DJ, Kim JM, Youn ... product. Introduction Hyaluronan (HA), a common component of connective tissue, is a long, unbranched nonsulfated glycosaminoglycan essen- tial for the normal function of diarthrodi...

Ngày tải lên: 09/08/2014, 08:23

... enzymatic activity is not altered by freezing of the samples, we conducted a pre-study comparing frozen samples and samples obtained after decapitation of animals on the same day of the enzymatic ... receptors. In addition, they have been shown to have pronounced effects on a variety of biological processes such as neuro- transmission, regulation of cardiac function and pl...

Ngày tải lên: 10/08/2014, 09:20

... inflammation as evidenced by pancreas MPO and histology (Fig. 2A and 2B) and pulmonary inflamma- tion, as evidenced by lung MPO and histology (Fig. 3A and 2B) and a significant reduction of inflammation ... regulation of inflammatory responses mediated by NaHS in pancreas and lung. Conclusions In conclusion in this study of acute pancreatitis induced by hourly caer...

Ngày tải lên: 11/08/2014, 08:22