Báo cáo y học: " Global expression profiling of theophylline response genes in macrophages: evidence of airway anti-inflammatory regulation" ppsx

... between laboratory features of the patients with RA and occurrence of mtDNA and oxidized DNA The laboratory findings for the patients with RA used in this study are shown in Tables 1 and 2. There ... immunos- timulatory mtDNA was involved in human arthritis by assay- ing the levels of extracellular mtDNA in plasma and synovial fluid (SF) samples from patie...

Ngày tải lên: 09/08/2014, 01:23

... article Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation Vyacheslav A Adarichev 1 , Csaba Vermes 1 , Anita Hanyecz 1 , Katalin Mikecz 1 , ... gene expression profile is extremely complex owing to the diversity of cell types involved in the pathology and the polygenic character of the...

Ngày tải lên: 09/08/2014, 06:22

... 3'-gttcgggaaccggattattta-3'; CDC2: 5'-ggtcaagtggtagccatgaaa-3' and 3'-ccaggagggata- gaatccaag-5'; and MKI67: 5'-ccccaaccaaaagaaagtctc-3' and 3'-gactaggagctggagggctta-5'. Histopathology ... 5'-gcccagctatgaactccttct-3' and 3'-tgaagaggtgagtggctgtct-5'; INDO: 5'-ggtcatggagatgtc- cgtaa-3' and 3'-accaatagagagaccagg...

Ngày tải lên: 09/08/2014, 14:20

... predominantly intracellularly [26,27]. Cathepsin H, cathepsin C, cathepsin F, cathepsin W, cathepsin B and cathepsin S are also increased in expression in OA tissue Table 3 Fold change and threshold cycle ... identified), particularly in the nervous system since the ADAM22 null mouse displays ataxia and peripheral nerve hypomyelination [20]. Following ectodomain shedding, some transme...

Ngày tải lên: 09/08/2014, 14:22

... accurate barcode sequences in a hap- loid fission yeast deletion library and validated them by conducting fitness analysis of barcoded fission yeast dele- tion strains in pooled cultures. The barcode ... characterization of the barcode sequences in the deletion library and describe a fitness- profiling pipeline that allows the analysis of a fission yeast h...

Ngày tải lên: 09/08/2014, 20:22

... 11:R85 http://genomebiology.com/2010/11/8/R85 Page 19 of 19 RESEARC H Open Access Digital expression profiling of novel diatom transcripts provides insight into their biological functions Uma Maheswari 1,2 , Kamel Jabbari 1,3 , ... S, Takahara M, Miyagishima SY, Mori T, Nishida K, Yagisawa F, Yoshida Y, Nishimura Y, Nakao S, Kobayashi T, Momoyama Y, Higashiyama T,...

Ngày tải lên: 09/08/2014, 20:22

... expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusion. Arthritis Research ... cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified b...

Ngày tải lên: 12/08/2014, 14:22

... by TGFβ included known target tropomyosin (TPM1). Interest- ingly, smoothelin, a smooth muscle gene recently reported to be highly induced by TGFβ in fetal lung fibroblasts [18], was also induced by ... GTP-binding pro- tein), involved in cytoskeleton remodelling, were also upregulated by TGFβ. TGFβ also induced Dickkopf1 (DKK1), a potent inhibitor of Wnt/beta-catenin signalling....

Ngày tải lên: 12/08/2014, 18:21

... [26]. In this study we investigated the role of Green tea extract in rodent model carrageenan-induced pleurisy. This experimental model has been widely used to investi- gate the pathophysiology of ... 1 of 13 (page number not for citation purposes) Respiratory Research Open Access Research Green tea polyphenol extract attenuates lung injury in experiment...

Ngày tải lên: 12/08/2014, 18:21

... H, Yajima H, Hitsuda Y, Matsumoto Y, Sasaki T: Functional assay of NF-kappaB translocation into nuclei by laser scanning cytometry: inhibitory effect by dex- amethasone or theophylline. Naunyn ... monocyte/macrophage biology, especially in atherogenic and inflammatory proc- esses [29,30]. Airway inflammation in asthma is regulated by a complex network of cytokines. We found that...

Ngày tải lên: 12/08/2014, 18:22

... properly cited. microRNA expression profiling of human breast cancer& lt;p>Integrated analysis of miRNA expression and genomic changes in human breast tumors allows the classification of tumor ... set of miRNA expression pro- files for primary human breast cancer we selected 99 primary human tumors, 5 normal breast samples and 33 breast cancer cel...

Ngày tải lên: 14/08/2014, 08:20

... control of hepcidin expression [23], in the B6 strain. Finally, and worthy of note within the context of modifiers of iron loading severity, wild- type D2 mice have significantly lower expression of ... Hfe- deficient B6 and D2 mice (two inbred mouse strains with divergent iron loading severity in response to Hfe disruption), to clarify the mechanisms o...

Ngày tải lên: 14/08/2014, 08:20

... were dominated by the signaling of inflammatory cytokines through the JAK-STAT (Janus activated kinase-signal trans- ducer and activator of transcription) pathway and the interac- tion of cell surface ... same system, as the focal adhesion pathway is activated by extracellular matrix- receptor interaction. Changes in extracellular matrix and associated proteins have...

Ngày tải lên: 14/08/2014, 08:21

... interactions information Open Access 2004Mandellet al.Volume 6, Issue 1, Article R1 Research Global expression changes resulting from loss of telomeric DNA in fission yeast Jeffrey G Mandell * , ... properly cited. Profiling yeast telomere shortening<p>Gene expression profiling of the response to <it>Schizosaccharomyces pombe </it>cells to loss of...

Ngày tải lên: 14/08/2014, 14:21

... simultaneously in the relevant cells, we excluded them from this study (Fig- ure 2a). In apparent contradiction of the prior theory [9], we find that the mean transcriptional variation of X- linked genes ... Issue 7, Article R74 Research Dosage compensation on the active X chromosome minimizes transcriptional noise of X- linked genes in mammals Shan...

Ngày tải lên: 14/08/2014, 21:20