Báo cáo khoa học: "The prevalence of the third and fourth heart sounds in clinically healthy Holstein cattle" pps
Báo cáo khoa học: "The prevalence of the third and fourth heart sounds in clinically healthy Holstein cattle" pps
... second heart sounds. One of the crite- ria used in this study to differentiate the third heart sound from splitting of the second heart sound was the effect of high heart rate on the third heart ... Splitting of the second heart sound usually remains unchanged when heart rate increases. In conclusion this preliminary study showed that the 3 rd and...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo khoa học: Co-operation of domain-binding and calcium-binding sites in the activation of gelsolin pptx
... 203–225, including one of the actin-binding sites, is in interaction with the C-terminal a-helix of G6 domain. The sequence 159–193, including the second actin interface, appears also in interaction ... number of repeated domains; six in the case of gelsolin itself, adseverin and villin, and three in capG, fragmin and severin (for a review, see [2]). The bind...
Ngày tải lên: 31/03/2014, 01:20
Báo cáo khoa học: "Transparent combination of rule-based and data-driven approaches in a speech understanding architecture" pot
... features. • Quantity of training data. • Modality (text or speech) of training data. We randomly divided the training corpus into ten equal pieces, and trained on subsets ranging from 10% of the corpus to the ... as a kind of backing-off mechanism, alleviat- ing the problem of data sparseness. Looking ahead, we are currently investigating several interesting extensions of...
Ngày tải lên: 08/03/2014, 21:20
Báo cáo khoa học: Making sense of G-quadruplex and i-motif functions in oncogene promoters pot
... contaminat- ing protein that is either an accessory protein or a minor recombinant protein [34]. Studies show that an R88A mutation (arginine to alanine) in the nucleotide- binding site eliminates ... (G-rich strand) and i-motif (C-rich strand) folding patterns and structures in the promoter regions of oncogenes. Accompanying minireviews in this issue discuss other aspects of...
Ngày tải lên: 23/03/2014, 03:20
Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... metal-binding site at the interface of the two domains, which consists of four side chains: two (His31 and His79) from the N-terminal domain and two (Asp165 and His169) from the C-terminal domain ... difference in number of ion pairs would be reflected in a corresponding difference in the stability of the proteins in organic solvents. Indeed, although the st...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt
... [35] may not be considered in the light of the results obtained in the present study. Rather, the involvement of manganese in the in vivo assembly of the metallocofactor of C. ammoniagenes R2F is ... this RNR and that of other class 1 RNRs or, instead, is a result of the interaction of the R2F with the inactivated (oxidized) form of the R1E. We co...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf
... inserted into the ACT2 domain; and (c) two ACT domains, each from a different chain, interact to form an effec- tor-binding unit. The effector-binding unit of the ACT domain in the b-subunit of CgAK ... in chains A and D, residues 53–59 in chain B, residues 55–56 in chain C, residues 56–57 in chain E, and residues 53–56 in chain F) of the loop between b3 and...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Limited suppression of the interferon-b production by hepatitis C virus serine protease in cultured human hepatocytes pptx
... IFN-b through the phosphorylation of multiple cellular factors, including IFN regulatory fac- tor-3 (IRF-3) and kinases, including the Tank-binding kinase 1 (TBK-1) and inhibitor of j B kinase e (IKK-e) [28–31]. ... serine prote- ase located in the amino-terminal domain of NS3. Ser- ine protease activity of NS3 requires NS4A, a protein consisting of 54 amino acid residue...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... of PKA in the mitochondrial targeting of CYP2E1 The role of PKA in mitochondrial targeting of CYP2E1 was investigated using two approaches. The first approach involved measuring the level of mito- chondrial ... resulting in the exposure of cryptic mitochondrial targeting signal, as in the case of CYP1A1 [4]; and (b) PKA- or protein kinase C-mediated phosphor...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Kinetic characterization of the first step of the ribozyme-catalyzed trans excision-splicing reaction docx
... to the GBS of the ribozyme for the exon-ligation step of TES. In the substrate-cleavage step, however, the 3¢ terminal guanosine (G336) of the ribozyme (Fig. 1) is binding to that same GBS. Therefore, ... for the second step of TES [48], similar to (if not the same as) the role of the xG in the second step of self-splicing [48–56]. This suggests that the...
Ngày tải lên: 18/02/2014, 18:20