Báo cáo y học: " Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients" docx

... with monocytes. (A) Flow cytometry expression of TLR2 and TLR4 on alveolar macrophages (AM)Figure 2 (A) Flow cytometry expression of TLR2 and TLR4 on alveolar macrophages (AM). rMFI (± SD) is shown ... autologous monocytes. Comparing AM we detected a reduced expression of TLR2 in COPD patients and smokers. In addition TLR2 mRNA and protein expression was...

Ngày tải lên: 12/08/2014, 18:21

... in cancer etiology is not yet fully understood. Although adiponectin may provide indirect protection against carcinogenesis by affecting insulin sensitivity and inflammatory states, it has ... analysis indicated that only the peritoneal dissemination was an independent prognostic factor on patient’s survival ( p = 0.001; Table 4). Discussion DiscussionDiscussion Discussion ....

Ngày tải lên: 10/08/2014, 10:21

... sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med 20 00, 28 :23 2 -23 5. 3 Adib-Conquy M, Adrie C, Moine P, Asehnoune K, Fitting ... be beneficial in the first place. Sepsis induces a complex immune response that is at times pro-inflammatory and at other times anti-inflammatory [21 ,22 ]. While CVVH can affect ci...

Ngày tải lên: 12/08/2014, 18:21

... low- dose insulin infusion depends more on the reduction in plasma glucose levels than on the dose of insulin administered in crit- ically ill patients [22 ]. Implementing tight glycemic control is associated ... gly- cemic on in- hospital outcome in diabetics. They suffer from a chronic state of insulin resistance, with inhibition of the insulin- signaling cascade by free fatt...

Ngày tải lên: 13/08/2014, 11:23

... 0.67 1. 32 (0.86 2. 01); P = 0 .20 a Control versus patients using the χ 2 test with 3 × 2 contingency table. b Control versus patients using the χ 2 test with 2 × 2 contingency table. c Early onset ... freedom. Available online http://arthritis-research.com/content/6/5/R415 R 421 phism and haplotype of three polymorphisms (PvuII in intron 1, XbaI in intron 1, and Bt...

Ngày tải lên: 09/08/2014, 01:23

... to the normalised results obtained from control condit ions (Aspergillus only) after 24 h and 48 h. The response of allergen expression upon incubation with macrophages is complex and clearly lacks ... allergy. Introduction Allergy is becoming one of the most common ailments in the developed world [1 ,2] . This condition arises from disproportionate IgE-mediated and/ or eosino...

Ngày tải lên: 13/08/2014, 13:22

... XKS1 -2- 2 2 4 0 -2 2 4 0 -2 0 2 -2 -4 0 2 -2 -4 0 2 -2 -4 0 2 -2 -4 0 -2 -4 0 -2 -4 4 2 0 4 2 0 Log2 Change in NucOcc Log2 Change in Fraction of H4Ac Log2 Change in Gene Expression Time (min) ... ‡ Laboratory of Genetics, University of Wisconsin-Madison, Henry Mall, Madison, WI 53706, USA. § Genome Center of Wisconsin, University of Wisconsin-Madison,...

Ngày tải lên: 14/08/2014, 21:20

... coupling and/ or synergism that can exist between cPLA 2 and sPLA 2 in various cells [3,13,33-35], sPLA 2 could conceivably be involved in chondrocyte destruction in RA by playing a role in bone ... L, Yamanishi Y, Karin M, Firestein GS: Joint dam- age and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis. Arthritis...

Ngày tải lên: 09/08/2014, 01:23

... mediators and cytokines related to bone destructionmRNA expression of inflammatory mediators and cytokines related to bone destruction. (a) Expression of mRNA for cyclooxygenase -2 (COX -2) and inducible ... Spain Corresponding author: Yasmina Juarranz, yashina@bio.ucm.es Received: 6 Apr 20 05 Revisions requested: 6 May 20 05 Revisions received: 17 May 20 05 Accepted: 2 Jun...

Ngày tải lên: 09/08/2014, 06:23

... University, Seoul, Korea. Authors’ contributions Conception and design: JYK, CWY, BHN, SL. Acquisition and assembly of data: CWY, BHN, HJS, HL, SKL, JYK. Data analysis and interpretation: BHN, HL, JYK, ... category 2 and 3 showed the clear discrimination in disease-free survival suggesting that CA 12 may offer additional dis- crimination ability in MD and PD tumors. Why would...

Ngày tải lên: 09/08/2014, 09:20