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Báo cáo y học: "Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A" ppsx

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Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"

... resuspended in 500 µL of ice-cold PBS and imme-diately analyzed by flow cytometry. For AnnexinV binding analysis 5 x 105 cells were washed once with PBS and resuspended in 500 µL AnnexinV Binding ... B19 infection, direct B19 NS1-induced cytotoxicity may play a role in idiopathic fulminant liver failure. Key words: Parvovirus, B19, Fulminant Liver Failure, Cytotoxicity, Apoptosis INTRODUCTION ... 2. AnnexinV Binding Assay. HepG2 cells were mock, EGFP-, NS1-, PathT-, or PathI-transduced, collected at indicated times post-transduction, and analyzed by flow cytometry for AnnexinV binding....
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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot

... expression increased in the aging thymus. The CCR5 ligands, CCL4 and CCL5, increase in the thymic parenchyma as revealed by the age-associated increases in the staining of thymocytes and microenvironmental ... immunoperoxidase staining using rabbit-anti-CCL4 or anti-CCL5 antibodies. Counterstaining was done with hematoxylin. CCL4 and CCL5 were detected in thymocytes and stromal cells in the thymic parenchyma. Multilocular ... to produce proin-flammatory cytokines and fat-derived peptides termed adipokines (including ligands such as adi-ponectin, leptin, resistin, TNF-α, IL-6), which act in a paracrine, autocrine...
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Báo cáo y học: "Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations." pps

... KIR3DS1 and theinhibitory 3DL1 are located in the intracytoplasmic tail. Theinhibitory receptor has a long tail containing immunoreceptortyrosine inhibitory motifs, whereas the activating receptor ... HLA-B27 by KIR orILT could influence their immunomodulatory function and mayimply a role in inflammatory disease.Binding of the KIR3DL1 receptor to the Bw4 family of MHCclass I receptors has ... it is reasonable to AS = ankylosing spondylitis; HC = heavy chain; HLA = human leukocyte antigen; HWE = Hardy-Weinberg equilibrium; ILT = immunoglobulin-like lymphocyte T receptors; KIR = killer...
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Báo cáo y học:

Báo cáo y học: "Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations" potx

... HLA-B27 by KIR orILT could influence their immunomodulatory function and mayimply a role in inflammatory disease.Binding of the KIR3DL1 receptor to the Bw4 family of MHCclass I receptors has ... susceptibility to ankylosing spondylitis. Curr Mol Med 2004, 4:13-20.Table 2Allelic and genotypic frequencies of KIR and HLA-B Bw4-I80 in patients with AS and B27 healthy controls in Spanish and Azorian ... it is reasonable to AS = ankylosing spondylitis; HC = heavy chain; HLA = human leukocyte antigen; HWE = Hardy-Weinberg equilibrium; ILT = immunoglobulin-like lymphocyte T receptors; KIR = killer...
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Báo cáo y học: " Expansion of the human mitochondrial proteome by intra- and inter-compartmental protein duplication" ppsx

... determined locali-zation in human and yeast, we reconstructed the (partial) protein complement of mitochondria of the common ancestorof human and yeast, comprising circa 200 proteins in total.Starting ... remaining yeastproteins (SEN2 and DNM1), unlike the 17 human mitochon-drial proteins, do not enter the yeast mitochondrion, butinstead attach to the outer membrane [26,27]. We can inferthe ancestral ... [62].Gene trees of mitochondrial proteins To take into account the evolutionary history of every protein, including gene losses and duplications, we performed analy-sis of individual gene trees...
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Báo cáo y học: " Vaughan-Jackson-like syndrome as an unusual presentation of Kienböck’s disease: a case report" doc

... 40-year-old man of Indian ethnic origin presented to our clinic without any history of trauma that he couldrecollect, an inability to extend the little and ring fingersof his right hand, and ... history of any other medical condition.He was right-hand-dominant and was unemployed atthe time of presentation.His physical examination revealed that he was unable to extend the metacarpal and ... wrist pain of 10days’ duration. He had had Cushing’ ssyndromeasachild and had undergone complete adrenalectomy in histeenage years. Since then, he had bee n on long-te rmsteroid therapy and said...
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Báo cáo y học: "Recurrent locked knee caused by an impaction fracture following inferior patellar dislocation: a case report." ppsx

... that such injuries can betreated by performing arthroscopy rather than an opensurgical procedure. This point is particularly relevantbecause as population demographics change and suchinjuries ... patella, andthen slowly extending her leg. Her knee was then placed in a camp splint and allowed to mobilize. The followingday the patient was able to raise and straighten her legwith a relatively ... legwith a relatively pain-free range of movement of theknee and was able to mobilize independently on theward. While in the hospital, she was unable to toleratethe splint and abandoned it. Her knee...
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Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report." doc

... in a young man about one year after he finished taking temozolomide. This shouldprovide further insight into a possible toxicity profile of this alkylating agent. This finding should be of interest ... alkylating agent; its safety profileand lack of data on any mutagenic potential has led to its incorporation in a large number of studies, for therange from malignant gliomas to malignant melanomas[11]. ... cytometry onimmunophenotyping with five-color cytomics (fc500Beckman Coulter flow cytometer) showed this popula-tion of cells with bright reactivity with Pan-T-markers(that is, CD5, CD7, and cytoplasm...
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Báo cáo y học: "Improving outcomes for ill and injured children in emergency departments: protocol for a program in pediatric emergency medicine and knowledge translation science" doc

... grant to KT ScienceKT research in emergency medicine (EM) is in its infancy, in part due to challenges specific to the ED setting. Theseinclude: the diversity of cases from minor to major andthe ... Despite the heightenedinterest in clinical guidelines, there remains much uncer-tainty about how best to introduce them into routinepractice [9-11], partially due to the varying effectiveness ofImplementation ... rigor-ous multi-centered studies; train and mentor students, fel-lows, and new researchers in order to increase clinicianand researcher capacity; and develop and advance aresearch agenda for methodological...
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Báo cáo y học:

Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report" potx

... Treatment ofCancer Brain Tumor and Radiotherapy Groups; National Cancer Institute ofCanada Clinical Trials Group: Radiotherapy plus concomitant and adjuvanttemozolomide for glioblastoma. N Engl ... gua-nines in DNA at the O6 position, causing base-pair mis-match. Unsuccessful cycles of mismatch repaireventually lead to breaks and permanent nicks in thedaughter strand, preventing mitotic ... neuro-oncologists prefer to use it i ndefinitely[9]. A recent survey of physicians who used TMZ formore than one year, on average, found it to be comple-tely safe, except for grade II and III myelosuppression[10]....
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