Báo cáo y học: " Antigen-sensitized CD4+CD62Llow memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting" pptx
Báo cáo y học: " Antigen-sensitized CD4+CD62Llow memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting" pptx
... produces Th2-type cytokines and directly induces transfer-mediated AHR. (A and B)CD4 + CD62L low memory/effector subset proliferates and produces Th2-type cytokines with antigen stimula- tion. ... proliferated there, then produced Th2-type cytokine, which resulted in the direct induction of AHR. They also indicated that anti- gen-pulsed memory/effector T cell phenotype might play...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ" potx
... suppressive activity of the T reg cells can be presented by plotting the percentage of inhibi- tion (100 × (Radioactivity in condition without T reg cells – Radioactivity in condition with T reg cells) /Radioactivity ... set of experiments we tested the importance of T reg cells in the pathogenesis of CIA by rendering wild-type mice deficient in T reg cells by tre...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo Y học: Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme pptx
... MCM2(169 21 2) domain interfere with the binding of pol II and general transcription factors in vitro. (A) The indicated amino acid substitutions were introduced into the GST- MCM2(169 21 2) peptide by ... It is therefore unlikely that the deletion mutants were recruited to GST– TFIIS via interactions with complexes that already contain endogenous MCM2. Fig. 6. Point mutations in the MCM2...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution pptx
... suggesting an important role in early stages of infection [3–6]. Vpr is involved in the transport of the preintegration complex into the host cell nucleus, which is an important feature for infection ... Cryst. 26 , 28 3 29 1. 28 . Hutchinson, E.G. & Thornton, J.M. (1996) PROMOTIF – a program to identify and analyze structural motifs in proteins. Protein Sci. 5, 21 2 22 0....
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates pptx
... due to the fact that it occurs within the instrument’s dead time [21 ]. None of the E139 FNR mutants show any detectable absorbance change in this reaction, which suggests again that the reactions ... different FNR mutants at E139 were determined for two reactions catalysed in vitro by FNR by fitting the experimental data to the Michaelis–Menten equation. Diaphorase activity. The analysis...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Controlling Osteogenesis and Adipogenesis of Mesenchymal Stromal Cells by Regulating A Circadian Clock Protein with Laser Irradiation" pptx
... regulated by osteoblasts that differentiate from mesenchymal stro- mal cells (MSCs). MSCs are multipotent cells that can replicate as undifferentiated cells and that have the potential to differentiate ... Class I cyclobutane pyrimidine dim- mers (CPD) photolyase, although it does not exhibit photolyase activity. CRY also binds flavin adenine dinucleotide (FAD), 2, 3 consist...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo y học: "Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis" pps
... demonstrated that IFN-γ Figure 6 Cytokine concentrations in joint extracts at different time points after the induction of antigen- induced arthritisCytokine concentrations in joint extracts at different ... 4b). Safranin O staining Safranin O staining reflects the proteoglycan content of cartilage. Proteoglycan loss is an early marker of cartilage destruction. The staining intensity o...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Polarized subsets of human T-helper cells induce distinct patterns of chemokine production by normal and systemic sclerosis dermal fibroblasts" doc
... quality and magni- tude as those induced by polarized T cells. For instance, IL-8 was not induced by any of the Th1 and Th2 cytokines, but was strongly induced by Th2 and to a lesser extent by Th1 cells ... levels induced by Th1 but not by Th2 cells (Figure 6a,b). Of further interest, MCP-1 mRNA induced by Th1 cells was not significantly affected by any of the inhibitors used, but th...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Predicting outcome of rethoracotomy for suspected pericardial tamponade following cardio-thoracic surgery in the intensive care unit" ppt
... parameters including, for worst values within 24 h prior to rethoracotomy, worst value within and at 24 h after rethoracotomy, and for those directly prior to and after rethoracotomy of, heart rate ... manuscript. Competing interests The authors declare that they have no competing interests. Received: 22 October 20 10 Accepted: 30 May 20 11 Published: 30 May 20 11 References 1. Weitzman...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Unusual association of ST-T abnormalities, myocarditis and cardiomyopathy with H1N1 influenza in pregnancy: two case reports and review of the literature" pps
... rkforce takes on added importance in the setting of the H 1 N 1 20 09 swine-origin influenza pandemic [22 ]. Inacti vated influenza vacci ne can be safely and effectively administered during any trimester of ... amongst caregivers to target this ‘at risk’ group aggressively with vaccination and prompt treatment. Introduction Many previous studies have explored the link between influenza...
Ngày tải lên: 10/08/2014, 23:22