... JC,Duffaut M, Pipy B, Vinel JP: Reactive oxygen intermediates and eicosanoid production by Kupffer cells and infiltratedmacrophages in acute and chronic liver injury induced in ratsby CCl4. Inflamm ... Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School, New Brunswick, NJ, USA3Professor of Environmental and Community Medicine, University of Medicine and Dentistry of New Jersey-Robert ... inflammatory cytokines in theliver [21]. ROIs in excess inactivate proteins, disrupt DNA, and oxidize lipids [22]. Preterm newborn infants may be par-ticularly susceptible to such injury because they...