... they gener- ated to compare the gene -expression profile of human embryos with that of human embryonic stem cells (hESCs) maintained in culture. ey found that approxi- mately 20% of the genes in ... early expression of PAX6 in humans (similar to their previous results with rhesus monkey embryonic stem cells), may have been a step in the evolution of the highly e...
Ngày tải lên: 09/08/2014, 20:22
... regula- tion of HO-2 expression in human cells under hypoxia. In the present study, we have analyzed the effect of hypoxia on the expression levels of HO-1 and HO-2 in various types of human cell line, including ... response during acclimatization to hypoxia. Results Effects of hypoxia on HO-1 and HO-2 expression in human cell lines We initially analyzed the effe...
Ngày tải lên: 19/02/2014, 06:20
Báo cáo y học: "Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis" ppt
... catabolic activity, including production of metalloprotein- ases [31,32]. IL-1 also stimulates chondrocyte expression of inducible nitric oxide synthesis, iNOS, which results in an increase in NO production ... 3 Catabolic factors induce the expression of HIF-1α protein in human articular cartilageCatabolic factors induce the expression of HIF-1α protein in human art...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: " Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b" doc
... pathway is involved in the TNF-α-mediated induction of Cyp7b activity in FLS. We studied the effects of inhibitors of different signal transduction pathways on Cyp7b activity in FLS by measuring Cyp7b ... the role played by TNF receptor II in regulation of Cyp7b activity. Thus, in order to study which signaling path- ways are involved in TNF-α-induced Cyp7b activity, we us...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis" ppsx
... following tissue injury in the upper urinary tract. Since the role of TGF-β1 in lower urinary tract inflammation is currently unknown, and since gender-based differences exist in the setting of interstitial ... predominant TGF-β1 effect in blocking iNOS induction. Given the time course of inflammation induced by CYP in our study, TGF-β1 is likely to emerge as a central mediato...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: "Serological and molecular expression of Hepatitis B infection in patients with chronic Hepatitis C from Tunisia, North Africa" pdf
... the type of interaction may depend on th e chronol- ogy of contamination with the two viruses: HCV super- infection in previously HBV infected patients, co-infec- tion or HBV infection in HCV ... HCV infection, as defined by persistent positivity of HCV serology and RNA for a minimum of 6 months. They were followed for their anti-HCV positivity in diff erent hepato-ga stroentero...
Ngày tải lên: 12/08/2014, 01:21
Báo cáo y học: " Azithromycin reduces spontaneous and induced inflammation in ΔF508 cystic fibrosis mice" potx
... [76] suggesting that reduction of the anti-inflammatory cytokine expression may be responsible for prolonged and excessive inflammatory response in CF. Events involved in imbalance of inflammatory cytokines ... that some of the benefits of azithromycin treatment in CF patients is due to modulating lung inflammation proba- bly by reducing, at least partly, cellular infiltration...
Ngày tải lên: 12/08/2014, 16:20
Báo cáo Y học: Evidence for general stabilization of mRNAs in response to UV light pdf
... resulted in activation of the p38 MAP kinase pathway, as determined by phosphorylation of recombinant HSP27 in in vitro kinase assays with cytoplasmic lysates (Fig. 5B, lower panel). The half-life of ... Miyazawa, K., Mori, A., Miyata, H., Akahane, M., Ajisawa, Y. & Okudaira, H. (1998) Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibrobl...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Physical Exercise and Quality of Life in Breast Cancer Survivors" potx
... easier. In our study only 10.7% of participants withdrew from the study: this surprisingly positive finding may be explained in terms of perceived quality of care related to the offering of custom-made ... inactivity secondary to treatment. The reduction in cardiopulmonary capacity may lead to reductions in quality of life [25, 26]. Research has provided preliminary...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "The use and abuse of commercial kits used to detect autoantibodies" ppsx
... reporting, and for laboratory inspection and maintenance. It is not clear that these standards are being met in routine practice. An interesting model of mandatory quality assurance and proficiency ... care system. It is appreciated that inappropriate laboratory testing (e.g. indiscriminate panel testing) is both costly and potentially misleading in the diagnostic workup. An estimation...
Ngày tải lên: 09/08/2014, 01:23