Báo cáo y học: " Airway epithelial cell tolerance to Pseudomonas aeruginosa" pps

... pathway, airway epithelial cells at 24 hours were likely exposed to released autocrine/paracrine factors that may have also contributed to tolerance. However, this was probably not mediated by IL-1β, ... pro-inflammatory cytokine and chemokine pro- duction [22]. Decreased cell surface TLR4 protein [23] was associated with tolerance, but tolerance could not be attributed solely...

Ngày tải lên: 12/08/2014, 18:21

... 148:1633-1637 7. Comolli JC, Waite LL, Mostov KE, Engel JN: Pili binding to asialo- GM 1 on epithelial cells can mediate cytotoxicity or bacterial in- ternalization by Pseudomonas aeruginosa. Infect Immun ... and airway epithelia, respectively [2,3,12–15]. This last point is still under review as recent evidence sug- gests that CF airway surface fluid may be isotonic not hypertonic...

Ngày tải lên: 12/08/2014, 18:20

... ICU stay to control aerobic Gram-negative bacilli, yeasts and Staphylococcus aureus; a parenteral antibiotic given immediately on admission to prevent primary endog- enous early infections; together ... administration delayed respiratory tract infection or colo- nization due to P. aeruginosa, and to evaluate the ability of L. casei rhamnosus to persist in the stomach. Outcomes The p...

Ngày tải lên: 13/08/2014, 11:22

... number of data-analysis strategies that are being developed, stan- dards are clearly needed. Metabolomics (like transcriptomics and proteomics) especially needs good databases to store metabolite ... fibroblast cell lines that led to the identification of changes in metabolic networks after pulsing cells with a labeled D-glucose tracer. Integrative biology was the theme of the talk by...

Ngày tải lên: 14/08/2014, 15:20

... Tschopp J: Inflammatory caspases: linking an intra- cellular innate immune system to autoinflammatory diseases. Cell 2004, 117:561-574. 33. Martinon F, Tschopp J: Inflammatory caspases and inflammas- omes: ... activates transcription factors such as nuclear factor-κB (NF-κB) and interferon regulatory factors (IRFs) that ultimately lead to tumor necrosis factor (TNF) and type I interfer...

Ngày tải lên: 14/08/2014, 20:22

... dissolved in the same vehicle every 2 wk for 4 wk (total: 3 times) to elicit allergic airway inflamma- tion according to the previous study by our laboratory [20]. The CSBG group received (12.5 ... pulmonary exposure to CSBG induces lung inflammation characterized by the infiltration of inflammatory leukocytes including eosi- nophils with an enhanced lung expression of proinflam- mato...

Ngày tải lên: 12/08/2014, 14:20

... necrosis factor (TNF)-α Hyperplastic type II cells [259,260] Cytokine receptors IL-2-receptor In vitro [261] TNF-receptor In vitro [262] Lymphotoxin-β-receptor Hyperplastic type II cells [263] Growth ... coagulation/fibrinolysis, and host defence. AE2 cells proliferate, differentiate into AE1 cells, and remove apoptotic AE2 cells by phagocytosis, thus contributing to epithelial repair. AE...

Ngày tải lên: 12/08/2014, 18:20

... chie-0011@k3.dion.ne.jp; Maki Tamayose - h066576@med.u-ryukyu.ac.jp; Akiko Miyazato - miyazato@saitama-med.ac.jp; Satomi Yara - f040621@med.u-ryukyu.ac.jp; Yuetsu Tanaka - yuetsu@s4.dion.ne.jp; Yoichiro Iwakura ... inflammatory cytokines and chemokines by HTLV-I-infected epithelial cells, in addition to that by infiltrating lymphocytes, may also play a role in the pathogenesis of HTLV-I...

Ngày tải lên: 13/08/2014, 05:21

... L. & Kolarov, J. (2000) The cytotoxic action of Bax on yeast cells does not require mitochondrial ADP/ATP carrier but may be related to its import to the mitochondria. FEBS Lett. 471, 113– 118. 31. ... been shown to modulate directly permeability transition pore opening [9], to regulate cell cycle checkpoints [10] by acting possibly on p53 transactivation [11,12] and to modula...

Ngày tải lên: 23/03/2014, 21:20

... a self-epitope also undergo apoptosis [9–11]. Therefore, circulating T cells in a healthy person normally possess a T -cell receptor repertoire selected to a self-epitope. Immune cells may be viewed ... normally intact third-party responses. Autologous HSCT appears to be reintroducing self -tolerance accompanied with a restoration of immune diversity, although the exact pathway(s) (e.g....

Ngày tải lên: 09/08/2014, 01:23