Báo cáo y học: "Inhibition of breathing after surfactant depletion is achieved at a higher arterial PCO2 during ventilation with liquid than with gas" ppsx
... study a ventilatory strategy of a moderate PEEP (0.5 kPa) and positive pressure ventilation at 60/ min was chosen in a model of surfactant depletion to sim- ulate a relevant clinical situation ... inspira- tory activity is inhibited at higher peak airway pressures and tidal volumes after lung lavage than before. In cats with surfactant- depleted lungs, inhibit...
Ngày tải lên: 12/08/2014, 18:21
... model of CF-related inflammation wherein NFκB is activated by filtrates of a clinically isolated strain of PA (PAF) led us to Withaferin A (WFA), a steroidal lactone from the plant Withania Somnifera ... treat Quantification of p65 translocation upon PAF stimulation and inhibition by WFAFigure 5 Quantification of p65 translocation upon PAF stimu- lation and inhibition by WFA...
Ngày tải lên: 11/08/2014, 08:22
... change in gene activity is the calcineurin-mediated activation of NFAT [44]. NFAT has been described as a signal integrator of Ca 2+ signal and other signaling pathways with induction of a specific genetic ... which attenuates SOC-medi- ated Ca 2+ influx, calcineurin activity and NFAT nuclear translocation. NFAT nuclear translocation is involved in hypoxia-induced TRPC1 up-...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemi" pot
... antibody. In marked contrast, the loss of diaphragmatic force production at 12 hours after LPS administration was greatly alleviated in animals pre- treated with anti-MCP-1 neutralizing antibody, as illustrated ... or with one-way or two-way ANOVA with post hoc application of the Tukey test to adjust for multiple comparisons. A statistics soft ware pac kage was used for all an...
Ngày tải lên: 13/08/2014, 21:21
Báo cáo y học: "Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass" pot
... Germany). Thin sections were contrasted with uranyl acetate and lead citrate, and viewed with a microscope (model JEM 2000 CX; JEOL, Arishima, Japan). Statistical analysis Statistical analysis was ... Ozdemir A: Hemody- namic and transesophageal echocardiographic analysis of global and regional myocardial functions, before and imme- diately after coronary artery bypass surgery. J C...
Ngày tải lên: 11/08/2014, 08:21
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... ERK1/2. Recent observations indicate that activation of Raf by PMA may trigger the same signaling pathway as oncogenic Raf, or Raf activation by Ras in combination with tyrosine phosphorylation [30]. ... of DNA synthesis and cell proliferation of human mammary myoepithelial-like cells by hepatocyte growth factor/scatter factor depends on heparan sulfate proteoglycans and sustained pho...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... lus ¯anking exons of genomic rabbit DNA was ampli®ed by PCR techniques. For PCR, the primers b-glb1/ P(5¢-AATCTGGTACCTCACCTGGACAACCTCAAA- 3¢)andb-glb2/M (5¢-AATAAGAATTCGCCAAAAT GATGAGACAGCA-3¢) ... turnover accompanied by the change in molecular ratio of lariat )3¢ exon and e xcised lariat compared with the splicing reaction without antibiotic was a clear indication that erythromycin...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... Netherlands. 25. Sohara, Y. , Ishiguro, N., Machida, K., Kurata, H., Thant, A. A., Senga, T., Matsuda, S., Kimata, K., Iwata, H. & Hamaguchi, M. (2001) Hyaluronan activates cell motility of v-Src-transformed cells ... HA synthesis pathway but not to stimulate the HA degradation pathway. In the present study, we showed that MU did not directly inhibit HAS activity even at a relativ...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... together [44], as our ATP binding data shows that little ATP is bound to the ATPase when it is added prior to curcumin. The fluorescence data of curcumin bound to the ATPase indicates that it may bind with ... fluorescence. ATP binding to Ca 21 -ATPase ATP binding to purified Ca 2þ ATPase was also measured using radiolabelled ATP as described by Champeil et al. [26]. Brie y, 0.3 mg·mL 21...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot
... mannosylated and the nonmannosylated ones). These data imply that higher concentrations of 2-deoxy- D-glucose affect not only GPtdIns mannosylation but also lead to more general effects on parasite ... plasma membrane (reviewed in [1–6]). GPtdIns from parasitic protozoa have been related to the pathology of many parasitic diseases [5]. The human malaria parasite, Plasmodium falciparum,...
Ngày tải lên: 31/03/2014, 23:20