Báo cáo y học: "Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation" potx

... attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation Harm Maarsingh*, Marieke A Tio, Johan Zaagsma and Herman Meurs Address: ... the pathophysiology of allergic asthma. Abbreviations cNOS, constitutive nitric oxide synthase; EFS, electrical field stimulation; eNOS, endothelial nitric oxid...

Ngày tải lên: 12/08/2014, 18:21

... obtained for the key role played by NO, whose production and release were also upregulated by ET-1. NO induces smooth muscle cell relaxation by activating sol- uble guanylate cyclase and by increasing ... Nakayama I, Tsuda T, Yokoyama M: Cyclic AMP-elevating agents induce an inducible type of nitric oxide synthase in cultured vascular smooth muscle cells. Synergism with the in...

Ngày tải lên: 09/08/2014, 06:22

... shown). This inhibitory effect was fully reversed by soluble YIGSR. Surprisingly , the inhibitory effect of coated YIGSR on PDGF-induced proliferation w as also fully normalized by soluble YIGSR. Of note, ... Gosens R: Airway structural components drive airway smooth muscle remodeling in asthma. Proc Am Thorac Soc 2009, 6:683-692. 8. Halayko AJ, Salari H, Ma X, Stephens NL: Marker...

Ngày tải lên: 12/08/2014, 13:22

... history and physical findings supplemented by the results of tests, including x-ray, angiography, ultrasound examination, the electrocardiogram, and occasionally a biopsy. The availability of ... commonly suspected to be lower on the islands than on the mainland (com- monly by people who have actually never visited the islands). We have assessed stress in the Panamanian mainland an...

Ngày tải lên: 31/10/2012, 15:12

... 2002 Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells Kentaro ... a-tocopheryl acetate; TN, a-tocopheryl nicotinate; TRAF, tumor necrosis factor receptor; TS, a-tocopheryl hemisuccinate; VSMC, vascular smooth muscle cells. Enzymes:...

Ngày tải lên: 22/02/2014, 04:20

... between control and 5-day exposed (P = 0.538) and 20-day and 5-day exposed (P = 0.119) rats. ** Significantly different from control, 5-day and 20-day exposed rats and * sig- nificantly different ... control and 5-day exposed rats (P = 0.789). ** Significantly different from control, 5-day and 20-day exposed rats and * indicates significantly different from control and 1-da...

Ngày tải lên: 12/08/2014, 18:21

... Enami T, Furukawa F, Imazawa T, Uneyama C, Fukushima S, TakahASHI M: Inhibitory effects of the dietary anti- oxidants butylated hydroxyanisole and butylated hydroxy- toluene on bronchioloalveolar ... Nitric Oxide 2004, 11:156-65. 56. Giri SN, Biring I, Nguyen T, Wang Q, Hyde DM: Abrogation of ble- omycin-induced lung fibrosis by nitric oxide synthase inhibi- tor, aminoguanidine in...

Ngày tải lên: 12/08/2014, 18:21

... 1993, 150:1908-1912. 28. Sampey AV, Hall PH, Mitchell RA, Metz CN, Morand EF: Regula- tion of synoviocyte phospholipase A2 and cyclooxygenase 2 by macrophage migration inhibitory factor. Arthritis Rheum 2001, ... was analyzed in the synovial lining cells (fibroblast-like and macrophage-like synoviocytes), sub- synovial nonlymphoid mononuclear cells (monocytes, macro- phages, and mast...

Ngày tải lên: 09/08/2014, 08:22

... these cells [12,13]. Mitochondrial fission and fusion, described recently and most extensively in dilated cardiomyopathy and ischaemic cardiomyopathy, occur constantly and are thought to be critical for ... immuno- histochemically stained with a specific primary antibody against von Willebrand Factor (vWF) (1:100, abcom). Capillary density was defined as the capillary to cardio- myocy...

Ngày tải lên: 10/08/2014, 09:21

... CA1, CA2 and CA3 areas and summated for each animal. Image analysis and statistical analysis Image J of NIH was used for densitometric analysis of Western blots and MBP ex pression density in the ... Taiwan. 5 Department of Physiology, Tzu Chi University, Hualien, Taiwan. 6 Department of Pharmacology, Tzu Chi University, Hualien, Taiwan. Authors’ contributions PCL and YTH carried ou...

Ngày tải lên: 10/08/2014, 10:20