Báo cáo y học: "Marked alveolar apoptosis/proliferation imbalance in end-stage emphysema" pdf

... pat- terns of inflammation in the two types of emphysema, as found in our study. A significantly higher increase of inflammation, particularly due to T lymphocytes, was found in AAT-deficiency emphysema ... role even in end-stage emphysema particularly in AAT-deficiency disease. The TGFβ-1 pathway does not seem to directly influence epithelial turnover in end-stage disease. In...

Ngày tải lên: 12/08/2014, 18:21

... primer). Results and discussion In marked contrast to previous findings, no polymorphic alleles (neither thymine at position 40 nor cytosine at position 1,400) were detected in any of the individuals tested. ... sur- prising because both positions were highly polymorphic in the original publications. In those publications, heterozygosity at position 40 (V14M) was detected in four in...

Ngày tải lên: 09/08/2014, 07:20

... leading to a predominance of Th2 cells [16]. Th2 cytokines, inter- leukins IL-4, IL-5, IL-10 and IL-13, increase in the skin while there is a corresponding decrease in Th1 cytokines, mainly interferon-g ... cells, inflammatory dendritic epidermal cells, monocytes, macrophages, lymphocytes, mast cells and keratinocytes.Allofthesecomponents interact through an intricate cascade of cytokines...

Ngày tải lên: 13/08/2014, 14:20

... Winchester RJ, Ginsberg HS: Human immu- nodeficiency virus type 1 strains in the lungs of infected indi- viduals evolve independently from those in peripheral blood and are highly conserved in ... redox-sensitive signaling mechanisms [31]. Finally, these effects on ZO-1 and occludin expression could be largely reproduced by treating naïve alveolar epithelial monolayers with gp120 or T...

Ngày tải lên: 10/08/2014, 05:21

... Gaylard D: Lingual nerve injury following the use of the laryngeal mask airway. Anaesth Intens Care 1999, 27:668. 8. Umapathy N, Eliathamby TG, Timms MS: Paralysis of the hypoglossal and pharyngeal ... paralysis following the use of the laryngeal mask airway. Anaesthesia 1994, 49:603-604. 3. Lowinger D, Benjamin B, Gadd L: Recurrent laryngeal nerve injury caused by a laryngeal mask airway. An...

Ngày tải lên: 11/08/2014, 00:23

... with overlying skin and a tiny grayish- whiteinguinalnodebiopsytissuepreservedin10% formalin. Microscopy showed oval to polygonal cells with eosi- nophilic cytoplasm delineated by thin fibrovascular ... difficulty moving his left leg. He was not diabetic or hypertensive. He had no other swelling. Examination r evealed a middle-aged man in painful distress with a solitary lymph node in the...

Ngày tải lên: 11/08/2014, 03:21

... with overlying skin and a tiny grayish- whiteinguinalnodebiopsytissuepreservedin10% formalin. Microscopy showed oval to polygonal cells with eosi- nophilic cytoplasm delineated by thin fibrovascular ... middle-aged man in painful distress with a solitary lymph node in the left inguinal region and non-pitting pedal edema in the affected limb. There was a fungating mass measuring 6×8 cm o...

Ngày tải lên: 11/08/2014, 07:20

... LPS interact synergistically to increase cytokine elaboration by AMs. Taken together, these find ings imply a signi ficant, unique role for sICAM-1 in modulating the inflammatory response to alveolar infections. In ... and MIP2 Having detected a trend to ward increased intra -alveolar cytokine and chemokine levels in SPC-sICAM-1 mice compared to wild-type mice in response to in v...

Ngày tải lên: 12/08/2014, 13:22

... University School of Oncology, Beijing Cancer Hospital and Institute, Fucheng Road, Beijing 100142, PR China. 4 Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, ... people living in Wuchuan County, a rural region in Northern China. Materials and methods The sampling methods of this survey among people aged 50 years and older living in Wuchuan Count...

Ngày tải lên: 12/08/2014, 15:22

Ngày tải lên: 13/08/2014, 01:20