Báo cáo y học: "Effects of PM10 in human peripheral blood monocytes and J774 macrophages" doc

... particles may exert their pro- inflammatory effects by modulating intracellular calcium signalling in macrophages leading to expression of pro-inflammatory cytokines. Impaired motility and phagocytic ... nacystelyn or the calmodulin inhibitor W-7. In human monocytes, PM 10 stimulated an increase in intracellular calcium which was reduced by verapamil, BAPTA-AM and nacystelyn....

Ngày tải lên: 12/08/2014, 18:21

... liver and the kidneys, were removed after death and directly fixed in 10% buffered formalin. Injured parts of the liver were cut into 3 mm thick slices. Only areas of maximum depth of injury and ... haematoxylin as counterstain was used. A blinded pathologist subse- quently assessed the degree of injury in the liver and of fibrin deposition in vessels and microthromb...

Ngày tải lên: 13/08/2014, 20:21

... potent inducer of CYP enzyme activity. Polymorphisms of CYP2B6 and CYP3A4 are associated with altered activity of hepatic enzyme in the liver and pharmacokinetics resulting in treatment efficacy. ... (62/65) of homo- zygous TT and 4.6% (3/65) of heterozygous TC, and 98.3% (58/59) of homozygous TT and 1.69% (1/59) of heterozygous TC in efavirenz and nevirapine g...

Ngày tải lên: 10/08/2014, 05:21

... activity, of moderate-intensity physical activity five to seven days a week by integrating short bouts of activity into the day, such as increasing the amount of walking, perform- ing more yard ... accumulated moderate-intensity LPA five to seven days a week, and asked to increase the daily duration of LPA by five min- utes each we ek. The five-minute increase in the daily duratio...

Ngày tải lên: 12/08/2014, 12:20

... tissues, including lung tissue [1]. Follow- ing bleomycin-induced injury in mice, mesenchymal stem cells colonized the lung and differentiate into type 1 or type II pneumocytes [2,3]. In addition, human ... previously described [16]. After fixation and paraffin embedding, 5 µm-thick lung sections were cut and stained with hematoxylin-phloxine-saffron. In each mouse, 30 intraacin...

Ngày tải lên: 12/08/2014, 15:20

... effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation. Clin Sci (Lond) 2008, 115:91-97. 31. Maines MD, Mayer RD, Ewing JF, McCoubrey WK ... Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase. Toxicology 2007, 241:92-97. 15. Ali MY, Ping CY, Mok YY, Ling L, Whiteman M, Bhatia M, Moore P...

Ngày tải lên: 13/08/2014, 21:21

... flurbiprofen. VAS scoring is a simple and often used method for evaluating variations in pain intensity. Subjects are instructed to indicate the intensity of the pain by marking a 100-mm line anchored ... Proinflammatory cy- tokines induce not only a local inflammation at the site of injury, but also systemic responses such as tachycardia, tachypnea, leukocytosis, and pyrexia...

Ngày tải lên: 25/10/2012, 11:10

... between Cyt f and plastocyanin and/ or plasto- cyanin and photosystem I, and subsequently the nature of the interactions in the two lineages (hydrophobic in cyanobacteria, electrostatic in chloroplasts) ... thermodynamic analysis by laser-flash absorption spectroscopy of photosystem I reduction by plastocyanin and cytochrome c 6 in Anabaena PCC 7119, Synechocystis PCC 6803...

Ngày tải lên: 21/02/2014, 01:21

... these proteins can be activated independently, suggesting that each link is func- tional [5–7]. In addition, in megakaryocytic cell lines and in primary megakaryocytes, the precursor of platelets, ... oncogene, which was in its activated state by constitutive binding of GTP. A number of proteins, including RAF, GAP p120 , MEKK1, and phos- phatidylinositol-3 kinase (PtdIns3K)...

Ngày tải lên: 08/03/2014, 16:20

... consumption-related psychopathology and multi- ple acquired deficits in physical and psychological health, in social life, family, work and financial well-being [34- 37]. Regarding physically ill individuals, ... probably be obtained in the facets of pain/discomfort (in the physical health domain) and in experiencing positive feelings (in the psychological health domain)....

Ngày tải lên: 08/08/2014, 23:21