Báo cáo y học: " The pattern of methacholine responsiveness in mice is dependent on antigen challenge dose" ppt

... assisted in the interpretation of results and editing the manuscript. PAS assisted in the interpretation of results and editing the manuscript. PGH assisted in the conceptualisation of the study ... an influence on the timing of peak responsiveness to bronchoconstricting agents. The aim of this study was to systemically investigate the effect of antige...

Ngày tải lên: 12/08/2014, 18:21

... spermatozoa; epididymis. Oxidation affects the spermatozoa in complex ways; either triggering hyperactivation or the suppression of motility largely d epending on conditions [1–3]. The quality of spermatozoa ... ystems. One is de novo synthesis from b uilding blocks, glutamate, cysteine, and glycine, via two ATP-con suming s teps involving c-g lut- amylcysteine synthetase ( cG...

Ngày tải lên: 17/03/2014, 17:20

... binding activates the enzyme–iron(II)-2-oxoglutarate ternary com- plex to oxygen binding, thereby initiating catalysis and ensuring coupling of 2-oxoglutarate conversion to prime substrate oxidation. In the ... these residues in binding the carboxylate linked to the nucleus of penicillin N (Arg160 and Arg162) and the carboxylate of the a-amino- adipoyl side-chain (Arg266...

Ngày tải lên: 18/03/2014, 01:20

... diagnosis by detecting both infiltrating eosinophils and t he presence of eosinophil degranulation when conventional eosin and hematoxylin staining of the tissue was not inter- preted as being significant ... did not have the classic clinical or laboratory features of myeloproliferation. Further, the mutation-related gain -of- function kinase specifically involved in the patho...

Ngày tải lên: 08/08/2014, 21:20

... participated in acquisition, analysis and interpretation of data and was involved in drafting the manuscript and revising it criti- cally for intellectual content. MWK contributed in acqui- sition of data ... was involved in interpretation of data. VNM participated in acquisition, analysis and interpreta- tion of data and was involved in drafting the manuscript. FAO-O...

Ngày tải lên: 08/08/2014, 23:21

... manage their pain for only a few days or weeks, it is unclear whether short-term inhibi- tion of COX-2 is really significant to the quality or timeli- ness of the healing. Indeed, the study by Zhang ... by 50% in the COX- 2-null cultures, but this effect was completely rescued by the addition of PGE 2 . The important question raised by these studies is whether patien...

Ngày tải lên: 09/08/2014, 01:21

... split the strongly linked genetic fragments controlling disease. The genetic effect may in fact be dependent on haplotypes rather than on single genetic polymorphisms. In spite of this, a number of genes ... susceptibility to arthritis in mice only in the presence of RIIIS/J alleles in the Cia32 locus, which also interacts with Cia31 and Cia26 [61]. Including i...

Ngày tải lên: 09/08/2014, 01:22

... anti-apoptotic mecha- nisms most likely play a critical role in maintaining the long-term activation of RA-SF and thereby contribute to matrix degradation. In addition to the expression of these anti-apoptotic ... inhibits the apoptotic process. Thus, the aim of this study was to investigate the expression profile of RA-SF during proliferation in comparison with that...

Ngày tải lên: 09/08/2014, 06:22

... type Spondyloepiphyseal dysplasia, Namaqualand type Spondyloepiphyseal dysplasia, Strudwick type Spondyloepiphyseal dysplasia, various types Spondyloepiphyseal dysplasia with precocious OA Spondyloperipheral ... combination of changes in both synthetic and degradative events [3]. The effects of mutations in the genes encoding these structural components of the matrix have prov...

Ngày tải lên: 09/08/2014, 06:22

... cited. Abstract In this study, we investigated the hypotheses that in human intervertebral disc (IVD) degeneration there is local production of the cytokine IL-1, and that this locally produced cytokine ... production by the cells of degenerate discs, especially in the NP [6], which, interestingly, were the same discs shown in this study to produce high lev- els of I...

Ngày tải lên: 09/08/2014, 06:22