Báo cáo y học: " Safety assessment of inhaled xylitol in mic

Báo cáo y học: " Safety assessment of inhaled xylitol in mice and healthy volunteers" ppsx

... OVA-sensitized/-challenged mice were characterized by airway eosinophilia in both saline- and xylitol- exposed groups (Table 1). In summary, aero- solized xylitol was well tolerated by naïve and hypersensi- tive mice ... Access Research Safety assessment of inhaled xylitol in mice and healthy volunteers Lakshmi Durairaj 1 , Janice Launspach 1 , Janet L Watt 1...

Ngày tải lên : 12/08/2014, 18:21

10
369
0

Báo cáo y học: "Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis" pot

... according to type during infusion period, postinfusion period, and for the total 28 days after initiation of infusion in all clinical trials Intracranial hemorrhage type During infusion period During ... Company, Indianapolis, Indiana, USA 3 Clinical Research Physician, Eli Lilly and Company, Indianapolis, Indiana, USA 4 Clinical Research Associate, Eli Lilly and Company, Indianapol...

Ngày tải lên : 12/08/2014, 19:22

9
229
0

Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx

... meniscectomy). Changes in collagen subtypes in pathological cartilage may not only influence the biomechanical integrity of the tissue but may sequester and modulate the actions of cytokines, with types ... OA chondrocytes synthesize SLRPs that are differently glyco- sylated, and that nonglycosylated biglycan and decorin are more abundant in OA cartilage [20]. Changes in gly...

Ngày tải lên : 09/08/2014, 06:23

10
416
0

Báo cáo y học: " Pharmacological characterisation of antiinflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation" ppt

... preclinical correlate to endpoints used in early proof -of- concept studies in man. Additionally, infiltrating inflammatory cells (particularly macrophages and lymphocytes) have been directly linked to ... would examine the same endpoints in the models as in the clinic. Typically, early proof -of- concept studies for COPD anti-inflammatory strategies in man assess inflammatory c...

Ngày tải lên : 12/08/2014, 11:22

10
328
0

Báo cáo y học: " The pattern of methacholine responsiveness in mice is dependent on antigen challenge dose" ppt

... IgE measurement and assessment of hyperre- sponsiveness to inhaled methacholine (MCh). Mice were sys- temically sensitised with two intraperitoneal injections of OVA/Alum on day 0 and 14, challenged ... to OVA in mice. The protocol used in the present study induced significant eosinophilia after a single airway challenge. The degree of eosinophilia increased with increa...

Ngày tải lên : 12/08/2014, 18:21

10
304
0

Báo cáo y học: "Global impression of perceived difficulties in children and adolescents with attention-deficit/hyperactivity disorder: Reliability and validity of a new instrument assessing perceived difficulties from a patient, parent and physician persp

... obtained by using other instruments that distinguish between various times of the day, such as the Daily Parent Rating of Evening and Morning Behavior (DPREMB) scale [14] or the Weekly Rating of ... Ng EML: Efficacy and safety of atomoxetine for attention-deficit/hyperactivity disorder in children and adolescents. Meta-analysis and meta-regression analysis. Psychopharmacol...

Ngày tải lên : 13/08/2014, 18:21

12
408
0

Báo cáo y học: "Global Assessment of Functioning (GAF): properties and frontier of current knowledge" docx

... for inclusion by looking for information on the following issues in relation to GAF: scaling, nature of anchor points, scoring of symptoms and functioning, scoring within 10-point intervals, psychometrics ... identification of symptoms (or grading of symptoms) that exclude scoring in the GAF-S interval 51-60 and make the interval 41-50 prefer- able. Proposing that the anchor...

Ngày tải lên : 08/08/2014, 23:21

11
441
0

Báo cáo y học: "Spectrocolorimetric assessment of cartilage plugs after autologous osteochondral grafting: correlations between color indices and histological findings in a rabbit model" ppt

... intramuscularly) and xyla- zine (7 mg/kg intramuscularly). The rabbits were placed in the supine position and surgery was performed on the left knee. After shaving and sterile prepping of the lower ... thereby improving joint function and decreasing joint pain. Several sur- gical techniques are currently used in clinical practice, namely debridement, microfracture, drilling, abr...

Ngày tải lên : 09/08/2014, 10:21

9
404
0

Báo cáo y học: "Immunohistological assessment of the synovial tissue in small joints in rheumatoid arthritis: validation of a minimally invasive ultrasound-guided synovial biopsy procedure" potx

... homogeneity of the cellular reaction in the upper subsynovial layer and the sampling potential of the US-guided biopsy, the proximal 600 μm of synovial sublining immediately adjacent to the lining layer ... development of a novel minimally invasive technique of US-guided synovial biopsy has been reported in the literature [23,31], and includes assessment of the small joi...

Ngày tải lên : 09/08/2014, 10:21

9
430
0

Báo cáo y học: "Ultrasound properties of articular cartilage in the tibio-femoral joint in knee osteoarthritis: relation to clinical assessment (International Cartilage Repair Society grade)" pptx

... the surgery. HK and KM participated in the analysis of the ultrasound indices. HK and KY performed statistical analysis. YN conceived of the study and participated in its design and coordination. ... Toshiya Sato, PhD, Professor of Biostatistics, Graduate School of Medicine, Kyoto University, for advising on the statistical analysis. References 1. Toyras J, Lyyra-Laitinen...

Ngày tải lên : 09/08/2014, 10:23

9
358
0