Báo cáo y học: "Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2" pptx

... lung fibrosis develops in the absence of MCP-1 or CCR2 To determine whether Aspergillus antigen- induced airway fibrosis develops in the absence of MCP-1 or CCR2, we measured lung hydroxyproline ... of 12 (page number not for citation purposes) Respiratory Research Open Access Research Aspergillus antigen induces robust Th2 cytokine production, in...

Ngày tải lên: 12/08/2014, 18:21

... unacceptably high morbidity, both in the short and long term. Therefore, off-label use of FVIIa in this setting is not only warranted but also potentially beneficial and life saving. Con: Recombinant ... gastro- intestinal bleeding) without any evidence for the drug’s efficacy and safety. The first issue is the off-label use. After a single successful report of off-label...

Ngày tải lên: 12/08/2014, 23:24

... characterized by elevation of the cytokines interleukin (IL)-4 and IL-5, which are respon- sible for the inflammatory cells infiltrating the airways. 32 Tumour necrosis factor a (TNF-a), IL-1b, and IL-6 ... local Th2 recruitment via control of cytokine production. 38 The hormone leptin of the IL-6 family has effects on inflammation, including the release of IL-6...

Ngày tải lên: 08/08/2014, 21:20

... selecting and ranking keywords, and searching OMIM text for selected keywords. Finding a QTL of interest The first step in finding candidate genes for a specific QTL is to choose a QTL of interest. ... his or her own and can automatically obtain the corresponding keyword values calcu- lated. These keywords can be used alone or together with the whole or parts of the...

Ngày tải lên: 09/08/2014, 06:22

... ignored. Intensive immunosup- pressive therapy, such as combined anti-thymocyte globulin (ATG) and cyclosporine (CSA), has an average onset of efficacy of 3-7 months and an efficacy rate of 60-80%. ... Before the onset of efficacy, patients are suscep- tible to severe infection. Moreover, infection shortly after treatment is a major cause of death in these patients and req...

Ngày tải lên: 10/08/2014, 21:23

... sensitivity but this depends on the severity of the symptoms. In our sample about 20% of the mothers scored above the cut-off for depressive symptom atology, although the majority of the sample ... received questionnaires from the psychology students during their first visits. The participants had the alternative of either sending the questionnaires back or ret...

Ngày tải lên: 13/08/2014, 18:21

... of the age of the participants and the setting in which the study was conducted only single items were chosen in the first two surveys for identifying affective and anxiety reactions, These items were ... longitudinal study of adults’ and children’s posttraumatic reactions and coping after the bus accident in Måbødalen, Norway, 1988. PhD thesis University of...

Ngày tải lên: 13/08/2014, 18:21

... (varying) definitions of left ventricular systolic dysfunction (ejection fraction <35% in the former and <40% in the latter). Neverthe- less, the trend was for the increasing value of pressure monitoring ... ventricular systolic function. This may help in refining fluid therapy and preventing harmful fluid overloading. Key messages • In patients after coronary ar...

Ngày tải lên: 14/08/2014, 07:21

... DNA-binding domain and two repressor domains interacting with corepressors CoREST and mSin3a. The corepressors additionally recruit the methyl DNA-bind- ing protein MeCP2, histone deacetylases ... regulation, including the timing and neuronal asymmetry in worm; growth control and apoptosis in fly; brain morphogenesis in zebrafish; and hematopoetic and adipocyte differe...

Ngày tải lên: 14/08/2014, 17:22

... draining lymph nodes, presenting antigens in the context of both MHCI and MHCII. Finally, DCs express co-stimulatory molecules and secrete polarizing cytokines necessary to initiate and shape the ... CD11c + DCs regulate the initia- tion of naïve CD4 + T cell responses in multiple ways, including carrying antigens to the draining lymph node, processing and presenting t...

Ngày tải lên: 12/08/2014, 11:22