Báo cáo y học: "Stem cells and repair of lung injuries" doc

... chimeric cells created by fusion, or lung cells gen- erated by transdifferentiation may all play a role in lung repair by promoting the local production of stem cells or reparative function of lung- specific ... wisdom of the body is to conserve stem cells. They cycle infrequently and the majority of cell replacement is accomplished by commit- ted progenitors within th...

Ngày tải lên: 12/08/2014, 18:21

... the understanding of stem cell biology. Interestingly, through more in-depth analyses, the known distribution of CD34 in vivo has recently expanded to include many of the key cell types that participate ... mobility and invasiveness and thereby facilitate traf- ficking of HSCs to the bone marrow and inflammatory cells to inflamed peripheral tissues [2,4,5]. In summary, the sam...

Ngày tải lên: 08/08/2014, 21:20

... thyrocytes on the fourth day of primary culture were exposed to thyrotropin (1 mUÆmL )1 ) for different lengths of time. Equal amounts of total cell lysates in Laemmli buffer were analyzed by standard ... regulated by the thyrotropin-activated pathways in dog thyroid cells. By differential screening of a chronically stimulated dog thyroid cDNA library, we identified several new differen...

Ngày tải lên: 23/03/2014, 21:20

... simple and effective means of controlling the fate of MSCs as a therapeutic strategy and act ‘molecular switch’ of regulatory proteins by suppressing CRY transcription. Furthermore, this model system ... detect calcium and calcium phosphate deposition, respectively. CRY is a key pro- tein for the differentiation of MSCs and bone nodule formation. Mice lacking Cry1 and 2 (...

Ngày tải lên: 08/08/2014, 17:20

... transplants develop thymic hypertrophy and a resurgence of thymic T cell output that contributes to the restoration of a wide T cell repertoire [29], although the intensity of thymic rebound declines ... approximately 50% of the increase in the number of T cells in the periphery, while the remaining 50% is due to enhanced peripheral expansion. Similarly, thymectomy decreases by...

Ngày tải lên: 09/08/2014, 10:20

... phagocytic cells of the monocyte/ macrophage lineage. Their rapid secretion of many factors that are also released by macrophages, lymphocytes and fibroblasts indicates that they can play similar ... Nelson M, Maloney W, Osdoby P: Receptor activator of NF- κκ B and osteoprotegerin expression by human microvascular endothelial cells, regula- tion by inflammatory cytokines, and r...

Ngày tải lên: 09/08/2014, 10:20

... muscularization of ves- sels and, in the nondeveloping adult lung, a mechanism which participates in lung tissue homeostasis and repair of injured lung cells via utilization of resident lung tissue precursor ... reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-spe- cific markers. Evidence for a dynamic and heterogeneous A hypothetical...

Ngày tải lên: 12/08/2014, 14:20

... analysis of the serological reactivity towards the HERV-H/-W Env peptide epitopes in sera Flow cytometric analysis of surface expression of HERV-H Env and HERV-W Env on B -cells and monocytes ... (SMS), healthy individuals (HC), and neurological non-inflammatory controls (NC)Figure 2 Flow cytometric analysis of surface expression of HERV-H Env and HERV-W Env on B -cells a...

Ngày tải lên: 12/08/2014, 23:22

... C). Clearly, the lysosome morphology differed Immunoelectron microscopy analysis of Gag distribution in MLV-infected cells and progeny virusesFigure 2 Immunoelectron microscopy analysis of Gag distri- bution ... supernatant. The use of chronically infected cells precludes reinfection with virion entry and ensures that only late phases of the viral cycle were observed. For cell...

Ngày tải lên: 13/08/2014, 09:21

... and culture of EPCs. TML and YW drafted the manu- script. JWB, LYM and XCX carried out the culture and the assay of EPCs. GEF conceived of the study, and participated in its design and coordination. ... target cells in pathogenesis of MODS. The regularity of the number and function of EPCs in MODS, however, remained unclear. To verify our hypotheses, we set up an a...

Ngày tải lên: 13/08/2014, 18:22