Báo cáo y học: "ICU Cornerstone: Changing our view of blood transfusions" pot

... engendered by the widely publicized infectious hazards of the transfusion of blood products. This underlying trepidation, spanning continents and cultures [15–17], spurred the careful examination of blood transfusion ... physicians will never view transfusion of blood and blood products in quite the same way. Competing interests None declared. Acknowledgments Supported by gr...

Ngày tải lên: 12/08/2014, 18:21

... ventilator. Now, after years of clinical experience with mechanically ventilated patients, I always look at the patient’s inspiratory effort and the ventilator delay to check whether there may be problems ... [4,5]. The clinically important thing was that, with any approach, we were able to monitor the improvement in the patient´s condition by examining the delay between the start of insp...

Ngày tải lên: 12/08/2014, 19:22

... mechanical ventilation. Keywords acute lung injury (respiratory distress syndrome, adult), high-frequency ventilation, hypercapnia, respiratory distress syndrome (infant), respiratory physiology 345 Available ... airway surgery, ensured that high-frequency positive pressure ventilation and certainly HFJV did find a niche in clinical Commentary ICU Cornerstone: High frequency ventilation is...

Ngày tải lên: 12/08/2014, 19:22

... can be formed. The ability to identify reliable surrogates of immunity (possibly in vivo assays of CD8 + T-cell medi- ated cytotoxicity) will be crucial to the testing of novel vaccine candidates. ... http://respiratory-research.com/content/2/3/157 commentary review reports primary research Respiratory Research Vol 2 No 3 Schluger whole cascade of inflammatory events. On the other han...

Ngày tải lên: 12/08/2014, 18:20

... sinus surgery would be extremely difficult to demonstrate because the incidence of serious complications is, fortunately, already very low. Image-guided surgery has not yet, and may never, become ... sinonasal anatomy and physiology which are well covered elsewhere and beyond the scope of this review. 1,2 Diagnostic Considerations Prior to beginning a discussion of surgical man- agement...

Ngày tải lên: 08/08/2014, 20:23

... generally focused on the activity of the cyclo-oxygenases, of which there are two isoforms: cyclo- oxygenase (COX)-1 and COX-2 (for review, see Smith and coworkers [65]). COX-1 is constitutively expressed ... JG, Nusing RM, Fritz P: Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: differential elevation of cyclooxyge- nase 2 in inflammatory joint diseases....

Ngày tải lên: 09/08/2014, 08:22

... play a part, but that moves beyond the scope of this review. People also vary in their ability to cope and their health beliefs. It has been hypothesized that small beneficial effects from psychosocial ... among psychosocial and other factors potentially associated with arthritis pain, disability, and quality of life. This paper is structured in two parts. It begins with an overview of...

Ngày tải lên: 09/08/2014, 08:23

... [73,74]. Eliminating TNFα by antibody therapy might therefore be beneficial not only by directly suppressing proinflammtory processes but also by restoring the suppressive function of Treg cells. Nadkarni ... the synovium of patients with RA and considered of importance in the migration of cells to the synovium (reviewed in [20]). A recent study by Kop and colleagues show that neutral...

Ngày tải lên: 09/08/2014, 10:22

... our knowledge of the pivotal role played by cytokines during the effector stages of human disease; has been instrumental in clarifying the place of cytokines in the maintenance and chronicity ... stimula- tion, as is often seen with exhausted lymphocytes, remains possible. Lymphocytes are scattered in the synovial sublining layer, and T cell-derived cytokines, with the exception of...

Ngày tải lên: 09/08/2014, 14:22

... GPP synthase lsu, GPP synthase large subunit; GPP synthase ssu, GPP synthase small subunit; HDR, 4- hydroxy-3-methylbut-2-enyl diphosphate reductase; HDS, 4-hydroxy-3-methylbut-2-en- 1-yl diphosphate ... diphosphate synthase; HPL, hydroperoxide lyase; kb, kilo base pair; LOX, lipoxygenase; Mb, mega base pair; MCT, 4-diphosphocytidyl-methylerythritol 2- phosphate synthase; MDS, 2-C-methyl-D-...

Ngày tải lên: 09/08/2014, 23:20