... TAA (in black). The superimpositioning was guided by the catalytic acids (D179AMY2, E204AMY2, and D289AMY2andD206TAA, E230TAA, and D297TAA). The invariant Y5 1AMY2and Y8 2TAAare ... arrow). Y5 1AMY2and Y8 2TAAare in orange. Otherbinding residues (W9AMY2, H92AMY2, T94AMY2, A9 5AMY2, Y1 30AMY2, A1 45AMY2, F180AMY2, K182AMY2, W206AMY2,S208AMY2, Y2 11AMY2, ... AMY2/acarbose(Fig. 1A) . Superpositioning of AMY2 and TAA guided by the catalytic acids was excellent for Tyr51AMY2andTyr82TAA(Fig. 1A) and mutation in Saccharomycopsisfibuligera a- amylase (closely related...