Báo cáo y học: " Tidal breathing flow-volume loops in bronchiolitis in infancy: the effect of albuterol [ISRCTN47364493]" docx
... at 10% of the remaining tidal volume; TEF25 = tidal expiratory flow at 25% of the remaining tidal volume; TEF50 = tidal expiratory flow at 50% of the remaining tidal volume; t PTEF /t E = the fraction ... 10% of tidal volume in the present study may suggest narrowing of the small airways after albuterol admin- istration. The ratio 25/PT will be influenc...
Ngày tải lên: 12/08/2014, 18:21
... progression of stage specific miRNA profiles in the mouse B2 B cell lineage. Blood 2011. 13. Calin GA, Pekarsky Y, Croce CM: The role of microRNA and other non- coding RNA in the pathogenesis of chronic ... inflammatory responses by mediating the expression of inflammatory genes in HUVECs [33]. Downregulation of miR-663 in tumor cells may contribute to aberrant cell...
Ngày tải lên: 10/08/2014, 21:23
... that bind to the SH2 domains. The tandem SH2 domains bind to Tyr-627 and Tyr-659 simultaneously in a specific orientation, in which Tyr-627 binds to the N-SH2 domain and Tyr-659 binds to the ... previously that G/G of the PTPN11 gene encoding SHP-2 increased the risk of gastric atrophy among the seropositive subjects [18]. The present study examined the associat...
Ngày tải lên: 31/10/2012, 15:37
Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc
... As both the E a of inactivation and the temperature at which the enzyme starts inactivating at a measurable rate increase from the apoenzyme to the Mn 2þ -containing enzyme, loss of the metal cofactor ... between the buffer and the enzyme by preincubating the enzyme–metal mixture at 30 8C for 30 min. Remaining activity was measured with glucose as the substrate in t...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors potx
... consider their effects on protein synthesis when studying the effects of these stress conditions on cell physiology. Other agents that inhibit protein synthesis (such as cycloheximide and anisomycin ... Enhanced Chemiluminescence (ECL) system (Amersham plc). Other assay procedures Rates of protein synthesis were assayed in CHO.K1 cells by measuring the incorporation of [ 35 S]meth...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... out in the presence of increasing concentrations of Ca 2+ calmodulin, the inhibition dropped by 50% in each case. In addition, these peptides also inhibit the activity of calcineurin, another enzyme ... with Ca 2+ calmodulin, they should also inhibit the activity of calcineurin. The four model peptides lesueurin, citropin 1.1, frenatin 3 and caerin 1. 9, all inhibit...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps
... of many MMPs increases in OA by either an increase in their own synthesis, an increased activation by their proen- zymes, or decreased activity of their inhibitors [29]. Pro- inflammatory cytokines, ... and bradykinin synthesis, since HA inhibited their synthesis in a MW-dependent manner [16]. Further, HA has been shown to induce analgesia in a bradykinin-induced model of joint...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "α Anti-α-fodrin antibodies do not add much to the diagnosis of Sjögren’s syndrome" pot
... autoimmune exocrinopathy of unknown origin. Therefore the diagnosis of SjS, in the absence of a gold standard, is based on cri- teria containing a number of subjective and objective signs and symptoms. In the ... indicating a disease sensitivity of IgG anti- bodies against α-fodrin of 48%. Nine (43%) of the 21 primary SjS sera were found to contain IgA antibodies aga...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Patients, their doctors, nonsteroidal anti-inflammatory drugs and the perception of risk" docx
... decision-making process leading to the use of the specific therapy remains daunting. The issue of the relative risk for a therapeutic in the context of its relative benefit should nonetheless continue ... When only small incremental benefits accrue to patients from the use of a given therapy, on the other hand, even very rare serious events may play a role in decisio...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "A second-generation autologous chondrocyte implantation approach to the treatment of focal articular cartilage defects" ppsx
... reported have included periosteal hypertrophy, ablation, uneven cell distribution, and loss of cells into the joint cavity [15,16], resulting in repetition of surgery in up to 25% to 36% of patients ... Despite these advances, most surgical inter- ventions only result in improvement in clinical symptoms, such as pain relief, and the regeneration of long-lasting hyaline car...
Ngày tải lên: 09/08/2014, 10:21