Báo cáo y học: "Bench-to-bedside review: Genetic influences on meningococcal disease" potx

... of meningococcal infections, but much is still unknown about the genetic background of contracting meningococcal disease. Genetic polymorphisms are com- monly prevalent, and newly found polymorphisms ... RJ, Harrison MM, Moxon ER, Tang CM: Underestimation of meningococci in tonsillar tissue by nasopharyngeal swabbing. Lancet 2000, 356:1653-1654. 3. Fogarty I, Cafferkey MT, Moloney AC:...

Ngày tải lên: 12/08/2014, 18:21

... juvenile Rhesus mon- keys reared with peers only, but not in monkeys who were reared with their mothers and peers during infancy. In contrast, monkeys carrying only the 'long' allele ... dominant) genetic, shared and non-shared environmental components. They normally do not separate gene-environment interactions (genetic sensitivity to environments) and gene-environment corre- lat...

Ngày tải lên: 13/08/2014, 18:21

... anti-inflammatory response syndrome [4]) after an inflammatory insult. Prolonged compensatory anti-inflamma- tory response syndrome may be associated with excess mor- tality and morbidity because of ... transition in the first intron of LT-α, has been identified as a potentially influential locus in many inflammatory conditions. This polymorphism is part of a complex haplotype including the n...

Ngày tải lên: 12/08/2014, 19:22

... complica- tions [25]. Clinically relevant hypertonicity suppressed degranulation and superoxide formation in response to N- formyl-methionyl-leucyl-phenylalanine (fMLP), and blocked the activation of ... of hypertonic saline infusion in various aspects of the pathophysiology of sepsis, including tissue hypoperfusion, decreased oxygen consumption, endothelial dysfunction, cardiac depression, a...

Ngày tải lên: 12/08/2014, 19:21

... namely the ‘neutrophilic hypothesis’, suggests that during acute inflammation the cytokines granulocyte colony-stimulating factor and granulocyte/macrophage colony-stimulating factor prolong the ... of cytokines by macrophages The third mechanism whereby apoptosis of neutrophils can modify the inflammatory response is by modulating the pro- duction of proinflammatory cytokines by alveolar mac...

Ngày tải lên: 12/08/2014, 19:22

... situations. Introduction The Commission recognizes the skill and dedication of so many individuals in the Ontario public health system and those volunteers from Ontario and elsewhere who worked beyond ... University of Toronto, Toronto, Ontario, Canada 3 University Health Network and Mount Sinai Hospital, and the Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ont...

Ngày tải lên: 12/08/2014, 20:21

... consumption, favourably modifying the balance of oxygen demand/supply. Consequently, it is an ideal application in post- cardiotomy cardiac dysfunction, especially in suspected coronary hypo ... brillation ECG, ABG, electrolytes Hypoxia, electrolyte abnormality Ventricular arrhythmias ECG, ABG, electrolytes Hypoxia, electrolyte abnormality Vasodilation Transpulmonary thermodilation, Decre...

Ngày tải lên: 13/08/2014, 19:20

... utilized by mitochondria to supply cellular energy through respiration and oxidative phosphorylation [2,3]. Oxidative phosphorylation conserves energy from the breakdown of carbon substrates ... die soon after Figure 1. Molecular oxygen use by enzyme systems leading to reactive oxygen species production and downstream consequences. Oxygen (O 2 ) not only leads to superoxide anion ( . O 2...

Ngày tải lên: 13/08/2014, 21:21

... Gonzalez-Gay MA, Martin J: The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to anky- losing spondylitis. Ann Rheum Dis 2008, 67:1451-1454. 44. McGeachy MJ, Chen Y, Tato CM, ... Australo-Anglo-Ameri- can Spondylitis Consortium (TASC), Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donne...

Ngày tải lên: 09/08/2014, 14:21

... diseases Primary pulmonary hypertension Secondary pulmonary hypertension Connective tissue diseases Congenital heart disease Acute lung injury Ischemia/reperfusion Pulmonary edema Acute respiratory distress ... alveolar cells. Pulmonary vascular disease Pulmonary hypertension is a rare and progressive disease characterized by increases in normally low pulmonary vas- cular tone, pulmonary vasc...

Ngày tải lên: 12/08/2014, 18:20