Báo cáo y học: "Physiology in medicine: importance of hypoxic pulmonary vasoconstriction in maintaining arterial oxygenation during acute respiratory failure" pdf
... authors noted that “… oxygen Review Physiology in medicine: importance of hypoxic pulmonary vasoconstriction in maintaining arterial oxygenation during acute respiratory failure Robert Naeije* ... iden- tification of the role of voltage-gated K + channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential...
Ngày tải lên: 12/08/2014, 18:20
... in designing of the study, acquisition of data, analysis and inter- pretation of the results, and drafting of the manuscript. SJ con- tributed to designing of the study, acquisition of data, and analysis ... expression in AAC are not clear. In a murine model, HIF expression is only sustained for a few hours in a hypoxic environment, implying that factors other than hypox...
Ngày tải lên: 13/08/2014, 08:20
... of Pharmacy, University of Maryland, Baltimore, Maryland, USA, 2 Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, Maryland, USA, 3 Departments of Psychiatry ... prevalence of antipsychotics in youth aged 0–4 ranged from 0.13% in Italy [24] to 0.5% in the Netherlands [29]. Generally, these antipsychotic prevalence findings closely matched...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "A Comparative Effectiveness Study of Bone Density Changes in Women Over 40 Following Three Bone Health Plans Containing Variations of the Same Novel Plant-sourced Calcium"
... nutritional industry. J Am Coll Nutr. 2009; 28:234-237. 38. Tunis SR, Stryer DG, Clancy CM: Practical clinical trials: in- creasing the value of clinical research for decision making in clinical ... Clicker, The Glycemic Index and the Glycemic Load, Estimating and Balancing Calories. In: Restructuring Body Composition: How the Kind, Not the Amount, of Weight Loss Defines a Path...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "β A randomized, controlled trial of interferon-β-1a (Avonex®) in patients with rheumatoid arthritis: a pilot study [ISRCTN03626626]" pptx
... G, Yong VW: Microglial production of TNF- alpha is induced by activated T lymphocytes. Involvement of VLA-4 and inhibition by interferonbeta-1b. J Clin Invest 1997, 100:604-612. 5. Coclet-Ninin ... two groups. Keywords: clinical trials, cytokines, interferon-β, rheumatoid arthritis, therapy Open Access R73 basis of the known side effects of the study agent), includ- ing flu-like sympt...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab" ppsx
... Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Function Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; CRP, C-reactive protein; ESR, erythrocyte ... al.: Two-year maintenance of efficacy and safety of infliximab in the treat- ment of ankylosing spondylitis. Ann Rheum Dis 2005, 64:229-234. 6. Braun J, Baraliakos X, Brandt J, Listing J, Zi...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis" doc
... primary source of which may be macrophages residing in the synovial lining layer of inflamed joints [31]. IL-15 produces a number of effects which may be relevant to the pathogenesis of arthritis including ... be markedly increased in arthritic paws from mice with CIA during the early phases of disease [24]. This may explain the efficacy observed following prophylactic adminis...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: "Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblast" potx
... [13]. There is increasing evidence that SFs are key players in the pathogenesis of RA by invading and eroding hyaline cartilage. SFs, activated locally, produce a variety of cytokines, chemok- ines and ... determine the final structures of glycans are glycosyl transferases and gly- cosidases. The significance of glycosidases has been recently suggested by studies in which glycosid...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Considerations for the inclusion of 2x mammalian genomes in phylogenetic analyses" ppsx
... characterized by a large number of assembly gaps and sequencing errors. In our original study [2], we quantified the impact of low-coverage genomes on inferences pertaining to gene gains and losses ... number of Figure 2. Increase in gene number through evolutionary time for all lineages (blue lines) in the latest Ensembl version (version 59). The red line indicates the lineag...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: " support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation" pot
... clusters. Finally, we ask whether the three cluster types are units of evolution, in th e sense that they are domains of preserved synteny, as observed in yeast [8-11]. Consid- eration of rates of synteny ... 15% of gene order conservation [19], as reuse of linkage breakpoints is influenced by the fragility of certain types of sequence (see, for example, [51,52]). We start...
Ngày tải lên: 09/08/2014, 22:24