Báo cáo y học: " Superantigen antagonist peptides" ppsx

... S. pyogenes infection [2]. One consequence of the cytokine storm induced by superantigens may be to disrupt the development of antibody-mediated immunity. By switching off superantigenicity, the ... synthesized by Staphylococcus aureus and Streptococcus pyogenes, which share the immunological property of being super- antigens. Superantigens are characterized by the ability to bypass normal .....

Ngày tải lên: 12/08/2014, 18:20

... 5200 (RLYR) 2 1950 (RLYR) 4 338 (RLYR) 8 48 Dendritic R4 (RLYR) 2 K 3700 (RLYR) 4 K 2 K 1510 (RLYR) 8 (K 2 K) 2 K 1514 Dendritic R8 RLYRKVYG 3950 (RLYRKVYG) 2 K 1420 (RLYRKVYG) 4 K 2 K 610 (RLYRKVYG) 8 (K 2 K) 2 K 112 Tachyplesin 108 928 ... determined accurately because o f its poor solubility in phosphate buffers, this peptide rapidly and quantitatively induced erythrocytes aggregations. Pr...

Ngày tải lên: 22/02/2014, 04:20

... vibra- tory urticaria are very rare. In physical urticaria the routine diagnosis is mainly limited to identify the subtype by appropriate standardized challenge tests [68]. The association of physical ... serology for streptococci (antist- reptolysin, antiDNase B), staphylococci (antistaphy- lolysin), yersinia (IgA, IgG, immunoblot). If an infection is identified, it should be appropriately t...

Ngày tải lên: 08/08/2014, 21:20

... ENPP1 variants should be genotyped in patients with severe disease at the hip, knee, or spine. The osteoarthritis research community is relatively fortunate in that many groups have collected OA ... OA cohorts suitable for genetic analyses [6], making confirmatory studies feasible. The genetic investigation of osteoarthritis has had a fillip in recent years, with compelling associations ... r...

Ngày tải lên: 09/08/2014, 07:20

... cytotoxicity [13]. Chronic obstructive pulmonary disease (COPD) and other inflam- matory lung diseases such as pulmonary fibrosis, α 1 -anti- trypsin deficiency, acute respiratory distress syndrome, ... the airways and the lung parenchyma from colonization and infection (Fig. 1). Components of the airway surface fluid (ASF) with antimi- crobial activity are lysozyme, lactoferrin, secretory ph...

Ngày tải lên: 12/08/2014, 18:20

... and colleagues examined the dynamics of DNA methylation as mouse embryonic stem cells (ES cells) progress to neural precursors and neurons in vitro. Intriguingly, very little change was found in ... methylation between pluripotent cells and their differentiated derivatives. The alterations observed occurred primarily at CpG-poor promoters, which under- went dynamic methylation and demethylati...

Ngày tải lên: 14/08/2014, 08:21

... not have xyloglucan endotransgly- cosylase (XET) activity and that XET lacks wall extension activity, either by itself or in the presence of xyloglucan oligosaccharides. 68. Yuan S, Wu Y, Cosgrove ... http://genomebiology.com/2005/6/12/242 Genome Biology 2005, 6:242 Expansins do not have hydrolytic activity or any of the other enzymatic activities yet assayed [64,66,67]. A report that they...

Ngày tải lên: 14/08/2014, 15:20

... University, Cambridge, USA) brought aspects of protein expression, abundance and stability into focus in her talk on yeast physiology, which included an impressive systematic analysis of extremely large ... antifreeze agents - as used by many animals to prevent freezing in winter. Hochstrasser noted that to simplify handling, protein samples can be digested by trypsin immediately after sampli...

Ngày tải lên: 14/08/2014, 15:20

... the Panther (Protein analysis through evolutionary relationships) Pathways database [http://www.pantherdb.org/pathway] by Paul Thomas (Applied Biosystems, Foster City, USA), we saw integration ... the diversity of data types. But there are also plenty of promising results, especially where a range of data sources can be integrated to give a coherent picture. The next five years of multi-genom...

Ngày tải lên: 14/08/2014, 16:21

... boom-bust cycles, peer review because they know that these young people haven’t had any experience writing proposals and anyway usually end up doing something different, or in a very different way, from what ... should be shortened to 15 pages. If you can’t describe clearly in 15 pages what you’ve already done, what you intend to do, and why it’s important, you probably can’t do it in 50. Bu...

Ngày tải lên: 14/08/2014, 16:21