Báo cáo y học: "The role of surfactant in asthma" ppsx

... surfactant dys- function by proteins was further disturbed by cooling [21]. This may explain the finding of increased airway resistance in patients with exercise-induced asthma where airway surfactant ... was initially thought to be a key player in the biophysical behavior of the lung, today its immunomodulatory properties make surfactant a fascinat- ing compound in innate and...

Ngày tải lên: 12/08/2014, 18:20

... consequently lead to increasing inter- est in the role of osteoclasts in local bone erosion that is driven by the hypothesis that synovial pannus makes use Review The role of osteoprotegerin in arthritis Georg ... Collagen-induced arthritis Species Rat Mouse Rat Dose 1 mg/kg/day 6.4 mg/kg/day 3 mg/kg/day Start Onset of symptoms Onset of symptoms Onset of symptoms Duration...

Ngày tải lên: 09/08/2014, 01:23

... scope of understanding of the basic pathophysiol- ogy of emphysema has advanced significantly in the past decade. It is becoming increasingly evident that elastin degradation alone cannot explain ... occur in smoking-induced emphysema. The macrophage, which is the predominant cell in the airways and alveolar spaces of emphysema patients, contains an array of enzymes capable o...

Ngày tải lên: 12/08/2014, 18:20

... consisted of using an isotype matched control antibody; excluding the primary anti- body (or the secondary enzyme conjugated antibody); or not incubating with the substrate-chromogen solution. Finally, ... colonisation of the upper and lower respiratory tract, and infiltration patterns of leukocytes into the lungs of infected mice were affected by the absence of SP-D. Pul- monary cl...

Ngày tải lên: 12/08/2014, 18:20

... & Penner-Hahn, J.E. (1998) Characterization of the zinc binding site in methionine synthase enzymes of Escherichia coli – the role of zinc in the methylation of homocysteine. J. Am. Chem Soc. 120, 8410–8416. 15. ... to ligation of the thiol group of coenzyme M. Mutations in His237 or Cys239, which are proposed to be involved in ligating zinc, resulted in an over 90...

Ngày tải lên: 17/03/2014, 23:20

... allergy. factors influencing development of the microbiota. Ann Med 1999, 31(4):288-92. 15. Kalliomaki M, Isolauri E: Role of intestinal flora in the develop- ment of allergy. Curr Opin Allergy Clin ... The role of the intestinal microflora for the development of the immune system in early childhood. Eur J Nutr 2002, 41(Suppi 1):I32-7. 18. Penders J, et al.: Molecular finger...

Ngày tải lên: 08/08/2014, 21:20

... an inflammatory challenge by altering production of proinflammatory and anti-inflammatory cytokines and may also affect cytokine signaling by a variety of mechanisms, including induction of SOCS-3 ... whereas in processes involving innate immunity, anti-inflammatory effects of leptin are prevalent. However, it is difficult to elucidate the role, if any, of leptin during inflammat...

Ngày tải lên: 09/08/2014, 08:22

... attempts an intervention, organizational mem- bers may already be conversing in ways that improve sensemaking and learning, or they may be conversing in ways that inhibit sensemaking and learning. The ... greatly in its novelty, ranging from the reinforcement of old beliefs or strengthening existing relationships and power structures to completely innovative ideas existing in the mi...

Ngày tải lên: 11/08/2014, 05:21

... breathing in genetically obese (ob/ob) mice. J Appl Physiol 1996, 81(2):716-723. 58. Inyushkin AN, Inyushkina EM, Merkulova NA: Respiratory responses to microinjections of leptin into the solitary tract ... possibly due to an increase in the number and maturation of alveolar type II cells, accompanied by an induction in the expression of surfactant proteins B and C [50]. Interes...

Ngày tải lên: 12/08/2014, 11:23

... the deficiency in catalase activity affected the lung inflam- mation induced by bleomycin. In BAL fluid, total numbers of inflammatory cells were increased after bleomycin administration in both types of ... 11:183 http://respiratory-research.com/content/11/1/183 Page 2 of 13 inflammation in acatalasemic mice after bleomycin administration. In bleomycin-induced lung injury ani...

Ngày tải lên: 12/08/2014, 13:22