Báo cáo y học: "Surfactant gene polymorphisms and interstitial lung diseases" pptx

... bron- chopulmonary dysplasia [30]. Conclusion In summary, genetic variations are factors in determining the development and severity of many ILDs. Surfactant plays an important role in lung physiology and ... superfamily. They are involved in host defense and recognize the carbohydrate moiety on the surface of pathogens. SP-B and SP-C are crucial in reducing surface Review Surfactan...

Ngày tải lên: 12/08/2014, 18:20

... Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team: Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery. Am J Kidney Dis 2005, ... FVL and glycoprotein IIIa PlA1/PlA2 gene polymorphisms and mid-term mortality or car diac morbidity after CABG [3]. Recently, Massoudy et al. have reported that the inci- dence o...

Ngày tải lên: 10/08/2014, 09:22

... of polymorphisms in Th1, Th2 cytokine genes with hayfever and atopy in a sub- sample of EPIC-Heidelberg. Clin Exp Allergy 2004, 34:346-353. 5. The European Community Respiratory Health Survey ... cytokine polymorphisms were genotyped. The associations of these polymorphisms with atopy were estimated by covariance and logistic regression analysis. Results: We confirmed IL4, IL10, IL6...

Ngày tải lên: 13/08/2014, 13:22

... percentages of MT2 cells in the G0G1, G2M and S phases of the cycle were respectively 89%, 3%, and 8%. For all clones, the cell cycle was assessed by flow cytometry at day 6 following PHA stimulation after ... for T lymphocytes, then restimulated. T lymphocytes were restimulated every 14 days with PHA (1 μg/mL) and fresh feeder cells (10 6 /mL). Lethally irradiated PBMCs from 3 distinct...

Ngày tải lên: 12/08/2014, 23:23

... purposes) Theoretical Biology and Medical Modelling Open Access Research Binary gene induction and protein expression in individual cells Qiang Zhang* 1 , Melvin E Andersen 1 and Rory B Conolly 2 Address: ... Andersen - mandersen@ciit.org; Rory B Conolly - Conolly.Rory@epamail.epa.gov * Corresponding author Abstract Background: Eukaryotic gene transcription is believed to occur i...

Ngày tải lên: 13/08/2014, 23:20

... het- erogeneity between the UK and Kenyan case-control groups for either SNP. The strongest association was with rs760477; on combining and stratifying the UK and Kenyan study groups, heterozygosity ... significance levels when multiple polymorphisms have been analysed, and confounding by population substructure. Nine polymorphisms were ana- lysed, and applying a Bonferroni corr...

Ngày tải lên: 14/08/2014, 07:21

... is contro- versial. Stability of gene expression may correlate more with the density of DNA methylation, as opposed to there being a binary ‘methylated’ or ‘demethylated’ state [36]. What controls ... 8, Issue 11, Article 228 Mok and Lever 228.7 Genome Biology 2007, 8:228 Genome Biology 2007, 8:228 Review Chromatin, gene silencing and HIV latency Hoi-Ping Mok and Andrew ML Lever Add...

Ngày tải lên: 14/08/2014, 08:20

... by checking for close homologs (by BLASTp) that might be absent from the gene family (because of the limitations of gene family assignment) and by building a smaller and more accurate phylogenetic ... Pasteurella, Vibrio, and Shewanella spp., which shows that these genes were acquired relatively recently. Because both arcA and dcuR are more closely related to genes from a variety...

Ngày tải lên: 14/08/2014, 08:20

... inflammation/infection and BPD The initial description of BPD by Northway, Rosan, and Porter [16] identified barotrauma and oxygen exposure as the causes of airway injury, fibrosis, and emphysema in ventilated ... increase 4 days after the endo- toxin stimulus and have increased 100-fold from control values by 7 days. The fetal sheep at 125-day gestation has very little SP-B in the...

Ngày tải lên: 12/08/2014, 18:20

... Brazilian [1] and Australian studies [5] were aware of the results of the study reported by Lellouche and coworkers [4], and tacitly incorporated the broader message of that study into their clinical ... of Bayes’ theorem and spectrum and test-referral bias. Intensive Care Med 2006, 32:2002-2012. 8. Nuland SB: The totem of medicine: Hippocrates. In Doctors: the biography of medicine...

Ngày tải lên: 13/08/2014, 16:20