Báo cáo y học: "Autocrine regulation of asthmatic airway inflammation: role of airway smooth muscle" doc

... the airways and lungs, as well as by cells that have migrated into the airway from the circulation. The release of pro-inflammatory mediators can induce airway hyper-reactivity and airway wall ... intensity of airway wall inflammation. A number of recent studies have shown that ASM cells are also a rich source of biologically active Review Autocrine regulation of asthmati...

Ngày tải lên: 12/08/2014, 18:20

... reperfusion ex vivo respectively the end-points feasibility and reliability. We conducted this study to clarify if another pathway of apoptosis induction in cardiomyocytes exists. Our aim was to ... concentration of ceramide employed in this study was 50 μM, similar to previous experimen- tal settings [12]. Amitryptiline Amitryptiline (systematic taxonomy: 3-(10,11-dihydro- 5H-dibenzo[[a,...

Ngày tải lên: 10/08/2014, 09:21

... pregnancy usually appearing during the third trimester of gestation and regress spontaneously after delivery. However, excisional biopsy is often required for the following reasons: 1) Unsatisfactory ... is generally required in the evaluation of a palpable mass, often dis- covered by the patient herself, or in the presence of a bloody nipple discharge, persistent axillary adenopathy, s...

Ngày tải lên: 11/08/2014, 19:21

... Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan 3 Smooth Muscle Research Group and Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, ... Ca 2+ -entry pathways regulated by vasopressin. Biochem J 2003, 370:439-448. 20. Kwan HY, Huang Y, Yao X: Regulation of canonical transient receptor potential isoform 3 (TRPC3) cha...

Ngày tải lên: 10/08/2014, 05:21

... aim ofthis studywas to characterize the role of an acyl-CoA thioesterase (ARTISt) and an acyl-CoA synthetase as members of an alternative pathway in the regulation of the intracellular levels of ... the critical role of acyl-CoA synthetases and thioesterases in the regulation of intracellular levels of AA and steroid produc- tion. This study further suggests a new concep...

Ngày tải lên: 08/03/2014, 09:20

... stress by redirect- ing t he synthetic machinery towards the synthesis of s ome enzymes involved in glycolysis or sugar-phosphate metabolism [54]. HydA belongs to a new class of Fe-hydrogenases HydA ... they often catalyze the reduction of pr otons with a high specific activity to yield hydrogen [16]. Interestingly, Fe-hydrogenases were not found in cyanobacteria, the free-living ancesto...

Ngày tải lên: 08/03/2014, 22:20

... differen- tiation in erythroid progenitors. Polycytemia vera is a clonal myeloproliferative disorder, leading to hyperproliferation of erythroid, myeloid and megakaryocytic cells. Sixty percent of polycytemia ... survival of early hematopoietic cells, at the expense of differenti- ation. The proto-oncogene c-Myb c-Myb is abundantly expressed in immature hematopoietic cells of erythr...

Ngày tải lên: 08/03/2014, 22:20

... telomerase activity was measured by TRAP/EIA cells 3 days later. (C) Telomerase activity after introduction of antisense oligonucleotides into PHA- stimulated lymphocytes. Ficoll-Hypaque isolated lymphocytes ... inhibition of TEP1 function by high concentra- tions of antisense oligonucleotides, telomerase activity was dramatically diminished. Alternatively, hTR and hTERT may play a mini...

Ngày tải lên: 17/03/2014, 23:20

... contrast, MMP-2 and MMP-14 (membrane type 1-MMP), are constitutively expressed, with minimal regulation, and they may have a relatively minor role in the pathophysiology of arthritis. Thus, the col- lagenases ... transcription of an array of inflammatory genes, their direct regulation of MMP transcription is just beginning to be elucidated. In the remainder of this review, we a...

Ngày tải lên: 09/08/2014, 03:24

... to bind to Tyr757 of gp130, Tyr985 of the leptin receptor and Tyr401 of the erythropoietin receptor, Tyr729 of the granulocyte colony-stimulating factor (G-CSF) receptor, Tyr800 of the IL-12 ... 279: 54708-54715. 66. Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, Wulf G, Rottapel R, Yamaoka S, Lu KP: Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ub...

Ngày tải lên: 09/08/2014, 06:23