Báo cáo y học: " Pharmacogenetics, pharmacogenomics and airway disease Ian P Hall" potx
Báo cáo y học: " Pharmacogenetics, pharmacogenomics and airway disease Ian P Hall" potx
... in the protein. This Review Pharmacogenetics, pharmacogenomics and airway disease Ian P Hall Queens Medical Centre, Nottingham, UK Correspondence: Professor Ian P. Hall, Division of Therapeutics, ... for polymorphic variation. The major- ity of data are from Caucasian populations and it is impor- tant to remember that differences in the prevalence of given polymorphisms can...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "Cystic fibrosis and renal disease: a case report" potx
... biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Journal ... can produce the same microvascular com- plications including nephropathy recognized in the non- cystic fibrosis patient populat...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: " The bioavailability and airway clearance of the steroid component of budesonide/formoterol and " docx
... pharmacoki- netic and pharmacodynamic properties of both compo- nents, such as the oral bioavailability and clearance, volume of distribution and speed of airway uptake, which may impact on the clinical ... the airways and therefore, has a greater chance of being removed from the airways by mucociliary clearance and cough [11]. These differences in lipophilicity may be particularl...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: " Innate immunity and monocyte-macrophage activation in atherosclerosis" potx
... adaptive immunity. Innate immunity is activated immediately upon encounter with the pathogen and is executed pri- marily by myeloid cells with the participation of some “innate” lymphocyte sub-populations. ... phenotypically plastic population than previously anticipated. In this review we focus on the role of macrophage activation and phenoty- pic polarisation in lesion formation and v...
Ngày tải lên: 11/08/2014, 06:22
Báo cáo y học: "Regulatory RNAs and the demise of ‘junk’ DNA" potx
... the impression that our understanding of the regulatory RNA world is still in its infancy. The situation was nicely summed up by Mattick in his comment “ and this is proba- bly just the tip of ... are common, and many may alter miRNA-regulated gene expression (see the Patrocles website [http://www.patrocles.org]). Their analysis strongly sug- gests that miRNA control of gene expression wil...
Ngày tải lên: 14/08/2014, 17:22
Báo cáo y học: "Isolated populations and complex disease gene identification" ppt
... processes. RReedduucceedd hhaapplloottyyppee ccoommpplleexxiittyy The increasing information in public databases on single nucleotide polymorphisms (SNPs) and their haplotype-tagging properties [42-44] as ... history and carefully phenotyped study samples is paving the way to a more comprehensive understanding of complex disease genetics. The scientific community might observe the resou...
Ngày tải lên: 14/08/2014, 20:22
Báo cáo y học: "Nicotine enhances murine airway contractile responses to kinin receptor agonists via activation of JNK- and PDE4-related intracellular pathways" pdf
... Terai Y, Takayama K, Miyata K, Yamada T: A novel phosphodiesterase type 4 inhibitor, YM976 (4-(3- chlorophenyl)-1, 7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one), with little emetogenic activity. J Pharmacol ... B 1 and B 2 receptors, and the house keeping gene glyceraldehyde-3-phosph ate dehydrogenase (GAPDH) were designed using Prime Express 2.0 software (Applied Biosystem, Forster city, C...
Ngày tải lên: 12/08/2014, 11:20
Báo cáo y học: " Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma" pdf
... voluntary ventilation; NAEPPII: National Asthma Education and Prevention Program II: NIH National Institutes of Health; PPP: per protocol population. Acknowledgements The A305 Study Group - Principal ... The study investigated sensitivity and spe- cificity of airway responsiveness to methacholine and mannitol to identify EIB and a physician diagnosis of asthma [13]. The study e xami...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: " Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation" pps
... drafted the manuscript. FMB participated in mouse experiments and conducted flow cytometry. CMTB participated in mouse experiments and manuscript preparation. MJ, AJC, and AAH participated in the design ... utilizedanoseonlysmokeexposureapparatus characterized by Shapiro et al [39], as opposed to a whole body smoke exposure system. A more likely explanation of the discrepancy is th e le...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: " Caveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSM" pps
... 13 (page number not for citation purposes) the FRET analysis. UP and GK carried out the quantitative RT-PCR. WK, GK, and PK analyzed the electron micro- scopic specimens. MD generated and genotyped ... damage and response. Clin Exp Allergy 2000, 30 Suppl 1:37-41. Respiratory Research 2006, 7:108 http://respiratory-research.com/content/7/1/108 Page 8 of 13 (page number not for citation...
Ngày tải lên: 12/08/2014, 16:20