Báo cáo y học: " Glycosylation and the cystic fibrosis transmembrane conductance regulator" docx

... case the authors reported that CFTR contained the insect glycosylation phe- notype and was not fully glycosylated. As the authors pointed out, the glycosylation phenotype is influenced by the ... α1,2-fucosyltransferase and sialyl transferase, then the activity of the latter two enzymes would be CF = cystic fibrosis; CFTR = cystic fibrosis transmembrane conduct...

Ngày tải lên: 12/08/2014, 18:20

... experiments and the microarray analysis. AK partic- ipated in the flow cytometory analysis. LQ participated design and analysis of part of the experiment. RC partici- pated in the design of the study. ... non-epithelial cells and cells of the immune system implies a variety of functions, including a possible regulatory role in the secretion of cytokines and antibodies by...

Ngày tải lên: 12/08/2014, 14:20

... [52-54]. Fibrocytes in the lumen of the airway After the fibrocytes have entered the tissue, the fibro- cytes can differentiate into other cell type s and/ or con- tinue to migrate to the lumen of the airway. ... and the ECM forms the basement membrane located under the epithelial and endothelial cells. The main components of the ECM are collagens, proteoglycans,...

Ngày tải lên: 12/08/2014, 13:22

... pres- sure and was discharged home the following day. At one-year follow-up with the Cystic Fibrosis C linic and the Neurosurgery Service, our pa tient was continuin g to do well with no signs or symptoms ... Chiari type I malformation in children and adolescents with cystic fibrosis. Pediatr Pulmonol 2000, 30:490-492. 5. Rakheja D, Xu Y, Burns DK, Veltkamp DL, Margraf LR:...

Ngày tải lên: 10/08/2014, 23:22

... follow-up sessions, the clinical condition of the patient as reported by the family and patient was recorded. The family as well as the patient were invited to discuss any problems that they encountered ... relative living with the patient in the same property, and who had maximum interaction with the patient or who was directly involved with the patient was included in...

Ngày tải lên: 08/08/2014, 23:21

... kidneys and nervous system. MS is an autoimmune disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to a broad spectrum of signs and symptoms. ... the expanding list of disease risk alleles and understand the effect on gene function. e first step is to identify which gene near the associated SNP has its functio...

Ngày tải lên: 09/08/2014, 20:21

... hypoxaemia in a woman with cystic fibrosis caused by thrombus formation in the right atrium. Case presentation: A 21-year-old Caucasian woman with cystic fibrosis and a totally implantable venous access ... Gyi 1 Addresses: 1 Department of Cystic Fibrosis, Royal Brompton Hospital and NHLI/Imperial College, Sydney Street, London, SW3 6NP, UK 2 Department of Cystic Fibrosis,...

Ngày tải lên: 11/08/2014, 14:20

... outcomes [6]. The primary objective of t his epidemiological study was to understand the relationship between sUA con- centration and CAC in relatively young and healthy adults. If the hyperuricemia-CAD ... Our study found a direct correlation between the prevalence and severity of CAC and sUA concentration in both men and women. This supports the hypothesis that uric acid...

Ngày tải lên: 12/08/2014, 15:23

... with the scav- enger receptor CD36 may facilitate fatty acid uptake by endothelial cells. Biochemistry 2001, 40(1):241-248. 63. Devery JM, King NJ, Geczy CL: Acute inflammatory activity of the ... are necessary for the clear and consistent detection of a lung inflammatory phenotype. In the study by Xu et al. [38], a series of micro- array analyses were performed to identify differen...

Ngày tải lên: 12/08/2014, 16:20

... animal strain and species, the challenge and sensitization protocol, and the phase of the response. The reasons for this are probably related to contributions by other CCR3 ligands, other chemokine ... mouse allergy model [44]. Many cell types in the lung appear to be capable of synthesizing eotaxin (eg airway epithelial cells, airway smooth muscle cells, vascular endothelial...

Ngày tải lên: 12/08/2014, 18:20