Báo cáo y học: " α Tumor necrosis factor-α and muscle wasting: a cellular perspective" docx
Báo cáo y học: " α Tumor necrosis factor-α and muscle wasting: a cellular perspective" docx
... pathway activates Jun-N-terminal kinases and the transcription factor AP-1. The third pathway activates NF-κB, a primary mediator of tran- scriptional control and a major candidate for catabolic signaling. ... pathways mediate the cellular response to TNF -α. One pathway stimulates apoptosis via interaction with the TNF -α- receptor complex and the Fas-associated protein with deat...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt
... RHS participated in the concept and design, analysis and interpretation of data, and drafting and revising the article. Acknowledgements The authors thank Dr. Sven Anders and Dr. Joachim Grifka ... expressed and produced in healthy and inflamed human synovial membranes. J Pathol 2002, 198:369-377. 9. Bokarewa MI, Jin T, Tarkowski A: Intraarticular release and accumulation o...
Ngày tải lên: 12/08/2014, 14:22
Báo cáo y học: "Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte" pptx
... (Promega) and luciferase activity quantified using the Dual Luciferase Assay System (Promega). Nuclear extract preparation and electrophoretic mobility shift assays Isolation of nuclear extracts and ... apoptosis were assayed by immunoblot with an antibody specific for intact and cleaved forms of poly(ADP ribose) polymerase (PARP). No cleavage of PARP (i.e. appearance of a band a...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes" ppt
... aorta. Arterioscler Thromb Vasc Biol 1999, 19:1333-1339. 17. Nozaki S, Kashiwagi H, Yamashita S, Nakagawa T, Kostner B, Tomiyama Y, Nakata A, Ishigami M, Miyagawa J, Kameda-Take- mura K, et al.: ... stimulated, or not, with a synthetic ligand of PPARγ, rosiglitazone (5 μM), and PPARγ activation was analyzed by gel-shift assay. Figure 3a shows a basal activation of PPARγ that was inhi...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis" pptx
... 5'-GCTCTC- CAGTCAGGAGCACT-3' and antisense 5'- CACACAGCACAGCAGACAAA-3', and GAPDH sense 5'- GAAGGTGAAGGTCGGAGTC-3' and antisense 5'-GAA- GATGGTGATGGGATTTC-3'. ... 5'-CCTA- CAGCCTCTGCTTACCG-3' and antisense 5'- GAGGGCAAAACAAGAGCAAG-3', STEAP3 sense 5'- GCCAGAAGAGATGGACAAGC-3' and antisense 5'-GGT- GCTCTTGCTCTG...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro" pptx
... cartilage. J Clin Invest 1997, 99:1534-1545. 31. Yoshihara Y, Nakamura H, Obata K, Yamada H, Hayakawa T, Fujikawa K, Okada Y: Matrix metalloproteinases and tissue inhibitors of metalloproteinases ... acquisition of data and part of the analysis of the data, and was also involved in drafting of the manuscript. AKL carried out the analysis and interpretation of mRNA data. RM made subs...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "α Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification" pps
... disorder. A few years ago, rheumatologists treating patients with ankylosing spondylitis (AS) had to accept the fact that the only goal of their proposed treatment was to alleviate pain and stiffness. ... inflammatory disorder. In the field of spondyloarthropathies (SpA), a group of diseases that present rheumatologically mainly with spondylitis, pauci- articular peripheral arthritis a...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Tumor necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells" ppt
... Watanabe E, Takagi T, Akiyoshi M, Ohtsubo T, Kihara S, Yamashita S, Makishima M, Funahashi T, Yamanaka S, Hiramatsu R, Matsuzawa Y, Shimomura I: Visfatin: A protein secreted by visceral fat that ... Segawa K, Fukuhara A, Hosogai N, Mortia K, Okuno Y, Tanaka M, Nakagawa Y, Kihara S, Funahashi T, Komuro R, Matsuda M, Shimomura I: Visfatin in adipocytes is upregulated by hypoxia through HI...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-B-dependent pathwa" pptx
... assistance of the Australian Microscopy & Microanalysis Research Facility at the Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, a facility funded by ... these enzymes include reduced availability of purines and pyrimidine s for DNA and RNA synthesis and accu- mulation of AICAR. AICAR, by inhibiting enzymatic deamination of adenosine a...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: "Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease" doc
... region. To type for TNF -α +489G /A polymorphism a PCR product was gener - ated using primer &apos ;A& apos; spanning +48/+67 (5'-GGAGA- GAAGCAACTACAGAC-3') and primer 'B' spanning ... (5'-TCTCGGTTTCTTCTC - CATCG-3') and primer 'D' spanning -675/-655 (5'- GAGTCTCCGGGTCAGAATGA-3'). The amplified DNA segments were analysed by dot blot...
Ngày tải lên: 12/08/2014, 18:20