Báo cáo y học: "Immunologists getting nervous: neuropeptides, dendritic cells and T cell activation" ppsx

... Vasoactive intestinal peptide and pitu- itary adenylate cyclase-activating polypeptide inhibit expres- sion of Fas ligand in activated T lymphocytes by regulating c-Myc, NF- κκ B, NF-AT, and early ... intra- Commentary Immunologists getting nervous: neuropeptides, dendritic cells and T cell activation Bart N Lambrecht Erasmus Medical Center Rotterdam, Rotterdam, The Neth...

Ngày tải lên: 12/08/2014, 18:20

... suggest that cyclosporin A may exert its therapeutic effect by inhibiting mast cell activation and by affecting the interaction between mast cells and nerves. Exogenous administration of neuropeptides to ... with other cells and physiologic systems. Mast cells can be divided into various sub- populations with distinct phenotypes. Mast cell secretory granules contain unique try...

Ngày tải lên: 08/08/2014, 20:23

... cell- cell interaction in the rheumatoid synovium. The essential factor in this situation appears to be the T cell- monocyte interaction to the extent that T- cell isolation renders the cells sensitive ... previously demonstrated that treatment with intra- articular glucocorticoids reduces the number of synovial tissue (ST) T cells in a wide range of arthritis types and suggest...

Ngày tải lên: 09/08/2014, 01:22

... apopto- sis is dependent on the complex cell- cell interaction in the rheumatoid synovium. The essential factor in this situation appears to be the T cell- monocyte interaction to the extent that T- cell ... flow cytometry. T cells were gated as CD3 + cells, and apoptosis was quantified as the mean percentage of Annexin V and 7- AAD + cells from the total number of gated ce...

Ngày tải lên: 09/08/2014, 13:22

... fishermen that lived at the study sites and had been fishing at that location for at least ten years. We interviewed a total of seventy fishermen. Their ages ranged between 40 and 60 years old, the ... management, it will be neces- sary to move beyond the symptoms of fishing and to take into account drivers of harvest pressure that result in potentially significant ecosystem change. One...

Ngày tải lên: 10/08/2014, 09:21

... observation suggests that arthritogenic Abs and T cells may briefly synergize to initiate inflam- mation but that continuous in vivo production of auto- Abs by B cells (probably in a T cell- supported ... after cell transfer. Treatment of recipient mice with FTY720 left the T- cell pool in the lymphoid organs intact, but reduced T cells in both peripheral blood and joint...

Ngày tải lên: 12/08/2014, 12:20

... in TLR9 recruitment between SLE and healthy pDCs may partly contribute to the lack of induction of Treg cells development in SLE, and this may further contribute to the tolerance break-down and autoimmune ... stimulated by pDCs were measured by percentage of CD4 + CD25 + cells per CD4 + T cells and compared with that of unstim- ulated T cells. To further investigate whether...

Ngày tải lên: 12/08/2014, 14:22

... We determined the lev- els of chemokines and cytokines in the BALF that have been reported to be important in recruiting and activating inflammatory cells to the airways and those that play a role ... from either rats instilled with saline or LPS at that time point (data not shown). Goblet cells and total epithelial cell number We have previously shown that LPS instillation resu...

Ngày tải lên: 12/08/2014, 15:20

... histological analysis, calculated the data and made substantial contribution to the analysis and interpretation of the data. WB contributed to the conception and design of the study, performed the ... experiments and revised the manu- script carefully. RRW contributed to the conception of the study and the data interpretation, and revised the manuscript critically. MO has made sub...

Ngày tải lên: 12/08/2014, 15:20

... monocytes, T cells, B cells, and neutrophils infiltrate the synovium and interact with each other to induce chronic synovitis [1,2]. Dendritic cells are efficient antigen-presenting cells, and ... spleen. Pretreatment of BM-DC with ZyA alone augmented T cell proliferation, but co-treatme nt with ZyAandTSAresultedinreducedTcellproliferation compared to that with ZyA alone, i...

Ngày tải lên: 12/08/2014, 15:23