Báo cáo y học: "Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthma" pps

... emphasis away from linkage analysis and microsatellite markers towards SNP genotyping and different analytical strategies based on association and haplotype analysis [31–34]. Association analyses ... pharmaceutical industry [4]. Asthma is a genetically complex disease that is associated with the familial syndrome of atopy and increased levels of total serum IgE [5,6]. Asthma and atopy...

Ngày tải lên: 12/08/2014, 18:20

... Medical Case Reports has published the case of a 22-year-old lactating woman who presented with four months of amenorrhea asso- ciated with signs of virilization. The patient was diag- nosed as having ... For example, ‘chemotherapy and radiotherapy’ are indicated in the branch of the ‘fishbone’ that shows the cause of ovarian failure, a potential cause for secon dary...

Ngày tải lên: 11/08/2014, 00:23

... of the analysis was 63 years (17–81 years), and 76% were female. A cohort of 171 healthy individuals matched on the basis of age, sex and origin were used as a healthy control group. All protocols ... the classification of the disease, were enrolled in the study. The 101 patients represented an ethnically homogeneous cohort of Caucasian RA patients. The median (r...

Ngày tải lên: 09/08/2014, 07:20

... Furukawa 2 , Yuya Kondo 3 , Satoshi Ito 3,4 , Taichi Hayashi 3 , Makio Kusaoi 5 , Isao Matsumoto 3 , Shigeto Tohma 2 , Yoshinari Takasaki 5 , Hiroshi Hashimoto 6 , Takayuki Sumida 3 and Naoyuki ... T, Graham RR, Hom G, Takasaki Y, Hashimoto H, Behrens TW, Sumida T, Tsuchiya N: Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control associ...

Ngày tải lên: 12/08/2014, 15:22

... plexity of the infl ammatory process: the shedding of membrane IL-18Rα as a marker of enhanced proteolytic activity; the activation and release of IL-18 by the infl ammasome as a marker of innate ... Matsunaga K, Sakazaki Y, Sawada M, Oda H, Takenaka S-I, Imaoka H, Kinoshita T, Honda S, Ida S, Fukuda T -A, Aizawa H: Soluble interleukin-18 receptor complex is a...

Ngày tải lên: 12/08/2014, 15:22

... antioxidant capacity [17]. Unfortunately, Abboud and colleagues did not report any of these measurements, and thus the impact of oxidative or nitrosative stress on the catecholamine clearance remains ... In addition, other authors have emphasized that the sepsis- related enhanced formation of nitric oxide and the superoxide radical O 2 - accelerates catecholamine deactivation du...

Ngày tải lên: 13/08/2014, 18:22

... cycle of che- motherapy were included in the toxicity analysis. Hema- tological toxicity grade ≥ 2 was observed in 22 patients, and grade 3/4 wa s seen in 12 patients. Hepatotoxicity grade ≥ 2 was ... histology, and o ther baseline characteristics were evaluated by logistic regression. Sur- vival was calculated by Kaplan-Meier method, and the log-rank test was used to determine the...

Ngày tải lên: 10/08/2014, 22:20

... LMP1-CD40 induces increased secretion of inflammatory cytokines and b-chemokines.Human inflammatory cytokine quantitation was performed by cytometric bead array (CBA). Cytokine concentrations from three ... with LMP1 and LMP1-CD40 adjuvanted virus. Human inflammatory cytokine quantitation was performed from the culture supernatants by cytometric bead array (CBA). P values are shown for an...

Ngày tải lên: 13/08/2014, 01:20

... increase in absence days/yr. A 10-day increase in ab- sence days per annum (scale score ranging from 0-220 days/yr) yielded an increase in disability pension risk of approximately 35% (Cochran-Armitage ... Study (DWECS) and the national register on social transfer payments (DREAM). DREAM is a register based on data from the Danish Ministry of Employment, the Ministry of S...

Ngày tải lên: 26/10/2012, 10:03

... that the probability of the parse of a equals 1/3, and the probability of the parse of ab equals 4/9. The parse of a can exhaustively be generated by applying rule (2), while the parse of ... language, .almost every input string of reasonable length gets an unmanageably large number of different analyses. Since most of these analyses are not perceive...

Ngày tải lên: 22/02/2014, 10:20