Báo cáo y học: " Matrix metalloproteinases in lung biology" ppsx
Báo cáo y học: " Matrix metalloproteinases in lung biology" ppsx
... matrilysin expression in other cell types, namely
macrophages, fibroblasts, and keratinocytes.
The widespread production of matrilysin in conducting
airway epithelium may be initially induced ... demonstrate that matrilysin is induced
by injury and is prominently expressed by migrating epithe-
lial cells. Although we do not yet know what process or
factor induces matrilysin in epithelia...
Báo cáo y học: "Matrix metalloproteinases and their inhibitors: promising novel biomarkers in severe sepsi" ppt
... important in the pathogenesis
and development of inflammatory diseases and are intimately
involved in the regulation of the activities of cytokines and
cytokine receptors [2]. Pathophysiologically, ... to
determine the cellular origin and the relevance of these
enzymes in sepsis.
Competing interests
MBr is an employee of Boehringer Ingelheim GmbH,
Germany. The other authors declare that...
Báo cáo y học: " Wnt signalling in lung development and diseases" pot
... signalling in
inflammation in the joint [34], we have addressed the
potential involvement of Wnt signalling in inflammatory
diseases of the lung.
Increased levels of pro-inflammatory and inflammatory
cytokines ... Furthermore, dominant negative and antisense Wnt5a
and anti-Fz-5 antibody block Wnt5-Fz5 signalling leading
to decreased cytokine production [33].
Additionally, the inflamma...
Báo cáo y học: "Genetic polymorphisms in lung disease: bandwagon or breakthrough?" ppt
... oxygenase-1 gene promoter may reduce the gene’s
inducibility by reactive oxygen species in cigarette smoke, thus
resulting in emphysema
Cystic fibrosis
HLA class II polymorphism in cystic fibrosis. A ... association between a poly-
morphism and disease exists can be greatly improved by
studying a more narrowly defined intermediate phenotype.
In the case of asthma, intermediate pheno...
Báo cáo y học: "Growth factors in lung development and disease: friends or foe?" pptx
... VEGF
are found in lungs of transgenic mice overexpressing inter-
leukin-13 [15]. Interestingly, accumulation of VEGF in the
alveoli appears to make these animals more resistant to
injury by hyperoxia ... aimed at restoring lung integrity. For example, diffuse
alveolar damage induced by hyperoxia in mice is acutely
associated with increased lung levels of FGF7 and FGF2,
which promote...
Báo cáo y học: "Accelerated decline in lung function in smoking women with airway obstruction: SAPALDIA 2 cohort study" ppsx
... baseline, change in weight, change in BMI
between surveys and years since quitting. Predictors in
each model are shown in the footnote to table 3. Baseline
lung function parameters were included in ... also increased by adjusting for years since quitting (p
= 0.02).
Decline in lung function per pack per day between surveys
was greater in men and women with a reduced FEV
1
/F...
Báo cáo y học: "Common variants in polygenic schizophrenia" ppsx
...
protein phosphatase nuclear targeting subunit encoded in
the MHC class I region strongly expressed in regions of
the brain involved in memory, learning, and Alzheimer’s
disease. Mol Brain Res ... disease, a finding in keeping with
other complex disorders [24]. In addition, the polygenic
inheritance of these variants and their contribution to the
overall phenotype diversity an...
Báo cáo y học: " Intravenous magnesium in subarachnoid hemorrhage" ppsx
... declare that they have no competing interests.
Published: 24 May 2011
References
1. Wong GK, Poon WS, Boet R, Chan MT, Gin T, Ng SC, Zee B: Intravenous
magnesium sulphate for aneurysmal subarachnoid ... placebo-controlled, clinical study. Crit Care
Med 2010, 38:1284-1290.
4. Schmid-Elsaesser R, Kunz M, Zausinger S, Prueckner S, Briegel J, Steiger HJ:
Intravenous magnesium versus nimodipine...