Báo cáo y học: " Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells" doc

... interleukin-8 and granulocyte–macrophage colony-stimulating factor delay neutrophil apoptosis by stimulating these pathways, and implicate the activation of PKB/AKT and the phosphorylation of BAD as ... resulting in the activation of multiple intracellular signalling cascades. These events regulate a broad array of cellular responses including survival, activation, differentiation and p...

Ngày tải lên: 12/08/2014, 18:20

... Nishida K, Furuichi T, Toki H, Nishimura G, Kawabata H, Yokoyama H, Yoshida A, Tominaga S, Nagano J, Shimizu A, Wakana S, Gondo Y, Noda T, Shiroishi T, Ikegawa S: A novel dominant-negative mutation ... Everman DB, Bartels CF, Yang Y, Yanamandra N, Goodman FR, Mendoza-Londono JR, Savarirayan R, White SM, Graham JM Jr, Gale RP, Svarch E, Newman WG, Kleckers AR, Francomano CA, Govindaiah...

Ngày tải lên: 09/08/2014, 13:22

... chronic inflammation in one or multiple organs [1]. During synovial inflammation, critical events include neo- angiogenesis, cellular hyperplasia, and a massive influx of inflammatory cells such as ... 1 The balance between pro- and anti-inflammatory cell types and cytokines dictates arthritic disease development. (a) During inflammation the joint is overwhelmed by an influx of pro-infl...

Ngày tải lên: 09/08/2014, 14:22

... Boulares AH, Yakovlev AG, Ivanova V, Stoica BA, Wang G, Iyer S, Smulson M: Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis ... machinery comprises a battery of transcriptional activators and repressors that form an auto-regulatory transcriptional feedback loop. Clock and BMAL1 are paired transcriptional activat...

Ngày tải lên: 10/08/2014, 09:20

... of symptoms. Discussion Femoral shaft fracture is usually caused by a high energy trauma. In this case it is possible that trauma energy was rotational and totally absorbed by the femoral shaft due ... close-locked intramedullary nailing [5]. In this case there was concern about the technical difficul- ties of antegrade nailing due to the distorted anatomy and the limited ability of int...

Ngày tải lên: 11/08/2014, 03:20

... is usually caused by a high energy trauma. In this case it is possible that trauma energy was rotational and totally absorbed by the femoral shaft due to the lack of motion at the dysplastic ... presentation: A 57-year-old Greek woman was admitted to the emergency department having sustained a spiral mid-shaft femoral fracture. She also suffered from an ipsilateral hip congenital dysp...

Ngày tải lên: 11/08/2014, 06:23

... Kilkenny L, Kinmouth A- L: Medically unexplained phys- ical symptoms in primary care: A comparison of self-report screening questionnaires and clinical opinion. Journal of Psycho- somatic Research ... see a 'rare' or novel condition may well be a generalist (something which is most likely in health care systems that have a strong and established primary care system). Se...

Ngày tải lên: 11/08/2014, 21:22

... to airway hyperresponsiveness and inflammation in a murine model of asthma. J Exp Med 1999, 189:1621–1629. 11. Grasemann H, Yandava CN, Storm van's Gravesande K, Deykin A, Pillari A, Ma J, ... Kamisaki Y, Wada K, Bian K, Balabanli B, Davis K, Martin E, Behbod F, Lee YC, Murad F: An activity in rat tissues that modifies nitrotyrosine- containing proteins. Proc Natl Acad Sci USA...

Ngày tải lên: 12/08/2014, 18:20

... Molecular Microbiology, NIAID, NIH Bethesda, Maryland 20892, USA Email: Kuan-Teh Jeang* - kj7e@nih.gov * Corresponding author Abstract In 1977, Takatsuki and co-workers described in Japan a human ... type I (HTLV-I), in a patient with cutaneous T-cell lymphoma. This month, Retrovirology commemorates these two land mark findings by publishing separate personal recollections by Takat...

Ngày tải lên: 13/08/2014, 09:21

... construction area as well as the availability of rapid transportation to and capacities of already existing nearby centers would have to be performed. Alternatively, a different approach would ... the availability of a pediatric trauma center upon the rates of admission and discharge of a disaster surge population by extrapolating from historical data. We find that the initial rate...

Ngày tải lên: 13/08/2014, 16:20