Báo cáo y học: " Interleukin-4 receptor α gene variants and allergic disease" potx

... in the inter- leukin 4 -receptor α gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet 2000, 66: 517–526. 2. Marsh DG, Neely JD, Breazeale DR, Ghosh ... Deich- mann KA: The polymorphisms S503P in the interleukin-4 receptor α gene are associated with atopy and influence the signal trans- duction. Immunology 1999, 96:139–144. 5. Hersh...

Ngày tải lên: 12/08/2014, 18:20

... present study shows that ER -α gene haplotype may be associated with primary knee OA, and genetic variations in the ER -α gene may be involved in OA. Keywords: estrogen receptor, haplotype, knee ... three polymorphisms in the ER -α gene (intron 1 T/C, intron 1 A/G and exon 8 G/A) and primary knee OA. Genotypes of the ER -α gene polymorphism were determined by PCR followed b...

Ngày tải lên: 09/08/2014, 01:23

... 0.06 respectively for FEV 1 ). Table 3: Analysis of glucocorticoid receptor genotypes and longitudinal trends for FEV 1 and FVC Total population F508del/F508del patients Genotype Y 6 (± SD) k (± SD) p Y 6 ... Respiratory Society and American Thoracic Society [24]. FEV 1 and FVC were expressed as percentages of predicted normal values. Res- piratory microbial flora was determine...

Ngày tải lên: 12/08/2014, 15:21

... the story. The effect of individual gene variants may be more precisely characterized by examining phenotypes closer to the biological activity of the gene in the context of PTSD [25,26]. Imaging genetic ... (5-HTTLPR) genotype and amygdala activation: a meta-analysis. Biological Psychiatry 2008, 63(9):852-7. 36. LeDoux J: Fear and the brain: Where have we been, and where are we g...

Ngày tải lên: 11/08/2014, 15:22

... Immunotherapy for Allergic Rhinitis — Passalacqua and Canonica 121 In healthy volunteers, the allergen sprayed into the nose is slowly transported by mucociliary clear- ance towards the pharynx (Figure ... that only SLIT and LNIT are viable alternatives to therapy by the injection route. 10 These conclusions were soon confirmed in a position paper by the European Academy of Allergology...

Ngày tải lên: 08/08/2014, 21:20

... and cathepsin L cleave collagen type II, type IX and type XI, and destroy the crosslinked collagen matrix at low pH [7]. Cathepsin K is also produced by osteoclasts and plays a key role in the degradation ... tissues by binding to hydroxapatite but that orally administered pyrophosphates are hydrolysed in the gut. Bisphospho- nates are resistant to hydrolysis and so could be adminis...

Ngày tải lên: 09/08/2014, 01:21

... Gonzalez-Gay MA, Martin J: The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to anky- losing spondylitis. Ann Rheum Dis 2008, 67:1451-1454. 44. McGeachy MJ, Chen Y, Tato CM, ... transgenic rat model, only genetically predisposed strains (Lewis or Fisher rats) with a high copy number of the transgene develop an inflammatory syndrome consisting of spondylitis, sacroiliitis...

Ngày tải lên: 09/08/2014, 14:21

... New Zealand Black/New Zealand White F1 mice display endothelial dysfunction and abnormal phenotype and function of endothelial progenitor cells. Lupus 2010, 19:288-299. 34. Lee PY, Li Y, Richards ... Biophys Res Commun 2009, 388:261-265. 50. Mok MY, Wu HJ, Lo Y, Lau CS: The relation of interleukin 17 (IL-17) and IL-23 to Th1/Th2 cytokines and disease activity in systemic lupus...

Ngày tải lên: 12/08/2014, 15:22

... negatively correlated with the mainly traffic-related pollutants, but positively with PM 10 and SO 2 , and it was only weakly cor- related with those of traffic-related and stationary fossil fuel ... temperature and relative humidity, are available from Taiwan Environmental Protection Agency in 1994 and later years. Concentrations of each pollutant are measured continuously and re...

Ngày tải lên: 12/08/2014, 16:20

... with symptomatic and asymptomatic asthma and modulation by histamine and interleukin-1. J Allergy Clin Immunol 1995, 96:618–627. 47. Fujitani Y, Trifileff A, Tsuyuki S, Coyle AJ, Bertrand C: ... airway epithelial cells and type II pneumocytes, which correlates with disease activity [166]. Scleroderma is commonly associated with pul- monary hypertension and pulmonary fibrosis. Plasm...

Ngày tải lên: 12/08/2014, 18:20