Báo cáo y học: " Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice" pot

... Access Research Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice Rachel A Collins 1 , Rosa C Gualano 2 , Graeme R Zosky 1 , Constance L Atkins 3 , ... poly-L-lysine and poly-L- arginine) increased airway responsiveness to inhaled MCh in rats [47], further investigation in isolated air...

Ngày tải lên: 12/08/2014, 18:20

... P=Pneumonia B A Respiratory syncytial virus (subtypes A and B) infection occurrence (No.) by calendar week in three epidemic waves during 2006 and 2007 (1 January 2006 to 31 December 2007)Figure 2 Respiratory ... Ehrnst A: Regular pat- tern of respiratory syncytial virus and rotavirus infections and relation to weather in Stockholm, 1984-1993. Clinical Microbiology a...

Ngày tải lên: 12/08/2014, 04:20

... protein, also known as CIN85 or SETA, is an adaptor-type protein belonging to the CD2AP/CMS family. It was found in complexes with many signaling proteins, including phos- phoinositol (PtdIns) ... proteolysis, causing an accumulation of proteins that are usually degraded by this pathway [22]. In contrast to lactacystine, which is a highly specific proteasomal inhibitor [23], ALLN inhib...

Ngày tải lên: 17/03/2014, 23:20

... involvement in RA [13]. The objective of this study was to examine if serological mark- ers widely used in daily clinical practice also can predict early involvement of bone measured by DXR in ... AJ, Reid DM: Predicting erosive disease in rheumatoid arthritis. A longitudinal study of changes in bone density using digital X-ray radiogrammetry: a pilot study. Rheumatology (Oxford)...

Ngày tải lên: 09/08/2014, 14:22

... cardiopulmonary bypass, coronary artery bypass grafting, inotropic support, epinephrine, dopamine, dopexamine, dobutamine, amrinone, enoximone, milrinone and levosimendan. Agents considered to be primarily ... resulting in increased concentrations of cyclic AMP (C-AMP), which in turn activate calcium channels to lead to increased cytosolic calcium, which increases the contractility...

Ngày tải lên: 12/08/2014, 20:21

... variable and this has led to much confusion in how to interpret studies and therefore in whether (or not) to accept new measuring or monitoring devices into routine clinical practice. Validation ... minute could be anything from 3 to 6 litres per minute (95% confidence). This may have profound clinical implications. In many clinical situations, there is no ‘normal’ cardiac outp...

Ngày tải lên: 13/08/2014, 11:23

... reduced by only approximately 50% com- pared with healthy volunteers. The reason for this discrepancy remains unclear. The use of epinephrine or norepinephrine instead of isoprenaline is unlikely to ... have expected reduced anti-inflammatory efficacy of rolipram in PBMCs of septic patients. Conversely, in our study, unchanged AC expression and maintained anti-inflammatory efficacy of r...

Ngày tải lên: 13/08/2014, 11:23

... A: Whole inactivated virus in uenza vaccine is superior to subunit vaccine in inducing immune responses and secretion of proin ammatory cytokines by DCs. In uenza Other Respi Viruses 2008, ... to be specifi c pathogen free, quarantined, and constantly monitored to make certain they remain disease free before entering the supply chain. A vaccine virus should be optimally ad...

Ngày tải lên: 13/08/2014, 20:21

... family. Finally, in vivo an ExoS protein lacking the 14-3-3 binding site is unable to ADP ribosylate cytoplas- matic proteins, e.g. Ras, and is impaired in its capacity to change the morphology ... morphology of infected cells. Keywords: ADP-ribosylation; coenzyme binding site; cyto- toxicity; NAD-dependent; peptide inhibitor. Members of the 14-3-3 family function as adaptor or scaffo...

Ngày tải lên: 31/03/2014, 08:20

... cells in the synovial sublin- ing [17,18]. Furthermore, inflammatory cells infiltrating the synovial tissue in RA and in the acute phase of CIA exhibit a predominantly Th1 pattern of cytokine expression ... = enzyme-linked immunosorbent assay; IDO = indoleamine 2,3-dioxygenase; IFN-γ = interferon-γ; IgGAM = immunoglobulins G, A, and M; IL = interleukin; i.p. = intraperitoneally; K =...

Ngày tải lên: 09/08/2014, 10:20