Báo cáo y học: "Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis" pps
Báo cáo y học: "Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis" pps
... peptides are released into the central circulation and may act systemi- cally, as opposed to many of the known mediators of sepsis, which are released locally and often act in an autocrine or paracrine ... nor- mally possess regulatory mechanisms limiting the expression of ProCT mRNA; these inhibitory mechanisms may be deregulated by unusually high levels of inflamma- tory...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: " Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis" ppsx
... other hand, the lack of endogenous IL-10, a prototypic anti-inflammatory cytokine, resulted in increased levels of TNF and enhanced mortality in mouse models of endotoxemia, whereas in models of ... apoptosis of the lung and distal organs. In addition, Gln acted on balancing pro- and anti- inflammatory cytokines, decreasing CINC-1 and IL-6 in BALF and PLF at 18 hours,...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: " Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease" potx
... limitations and advantages. The most important finding of the present study is that the adverse physiological consequences and likely, any related inflammatory or early remodeling changes attributable to ... indices and micro-CT imaging. Methods Experiments were approved by the Institutional Animal Care and Use Committee of the University of Vermont. Animals and the OVA Allergic A...
Ngày tải lên: 12/08/2014, 11:20
Báo cáo y học: " Multi-symptom asthma is closely related to nasal blockage, rhinorrhea and symptoms of chronic rhinosinusitis-evidence from the West Sweden Asthma Study" doc
... or less constantly?"; Family history of asthma: “Do any of your parents or sibling have, or have had, asthma ?"; Family history of allergy: “Do any of your parents or sibling have, or ... (%) 60 Non-asthma Fewer-symptom asthma Multi-symptom ast hm a Number of symptoms o f chronic rhinosinusitis Four symptoms Three symptoms Two symptoms One symptom Figure 5 Prevalence of...
Ngày tải lên: 12/08/2014, 11:23
Báo cáo y học: " Hospital employees’ theoretical knowledge on what to do in an in-hospital cardiac arrest" doc
... following versions of the manuscript. MLSK also partly participated in the statistical analysis. ME participated in the design and planning of the study and were involved in drafting the manuscript ... Health care professionals were recruitedatoneintervention- and one control hospital in the county of Västmanland, Sweden (a total of 3144 individuals). Intervention and control...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: " Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients" ppsx
... characterized by cell cycle arrest, inability to proliferate, and reduced cytokine synthesis (interferon-gamma (IFN-g)orIL-2orboth [21-24]). The co-inhibitory PD-1 system has been stu- died mainly in viral ... Bone RC: Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome). JAMA 1992, 268:3452-3455. 17. Landelle C, Lepape A, Francais A, Tognet E,...
Ngày tải lên: 14/08/2014, 08:21
Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... Specifically; tacro- limus is mainly metabolized by CYP3A4 and CYP3A5 enzyme isotype. CYP3A5 polymorphisms seem to affect tacrolimus kinetics at a greater degree com- pared to CYP3A4 ones and thereby, ... therapeu- tic index and its highly pharmacokinetic variance may lead to overtreatment and toxicity or insufficient treatment and transplant rejection, conditions that are usuall...
Ngày tải lên: 26/10/2012, 09:32
Báo cáo Y học: Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans doc
... elegans dystrophin and dystrobrevin are able t o bind to each other in vitro [18] in the same way as their mammalian counterparts [12], and they also bind to syntrophin [18]. dys-1 and dyb-1 mutants ... protein (reviewed in [1]). Dystrophin is a submembrane protein associated with a transmembrane dystrophin–glycoprotein complex (DGC) comprising dystroglycans, sarcoglycans, sarcosp...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo y học: "Sigma-1 receptor agonist fluvoxamine for postoperative delirium in older adults: report of three cases" docx
... Furuse and Hashimoto Annals of General Psychiatry 2010, 9:28 http://www.annals-general-psychiatry.com/content/9/1/28 Page 2 of 3 remains anonymous and there is no reason to think that the ... that fluvoxamine could be an alternative approach to treating postoperative delirium in older adults because of the risk of extrapyramidal side effects and increased mortality by antips...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps
... extension of immune reactivity from an initial region of strong antigenicity towards a polypeptide into other epitopes of the autoantigen, or even from an epitope in one polypeptide to another polypeptide ... autoantigen protein disorder has led us to an explicit model of epitope spreading that explains many of the paradoxical aspects of autoimmunity – in particula...
Ngày tải lên: 09/08/2014, 07:20