Báo cáo y học: "Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines" doc

... al.: Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines. Arthritis ... concentrations of pro -inflammatory cytokines. Glucocorticoid treatment of cartilage can effectively abolish matrix degradation induced by...

Ngày tải lên: 12/08/2014, 18:20

... One possibility lies in the well-documented ability of dietary omega 3 fatty acids to reduce inflammatory cytokines [40], since inflammatory cytokines have the ability to increase pro- tein degradation ... degradation mainly by activating the ATP-ubiqui- tin-dependent pathway [41-45]. It is possible then, that dietary fish oil is simply decreasing the breakdown of protein tiss...

Ngày tải lên: 11/08/2014, 23:21

... variability of efavirenz concentrationsisstronglyinfluencedby CYP2B6-516TT genoty pe by the f inding of significantly higher plasma e favirenz concentration at weeks 6 and 12 of ART and 1 month after ... potent inducer of CYP enzyme activity. Polymorphisms of CYP2B6 and CYP3A4 are associated with altered activity of hepatic enzyme in the liver and pharmacokinetics resu...

Ngày tải lên: 10/08/2014, 05:21

... main- tained till the early morning and then decreases again rap- idly to the extremely low concentration typical of the daytime [7,8]. The increase in melatonin concentration might occur in ... night increase in blood melatonin level as a direct effect and possibly delay the circadian system that drives the mela- tonin secretion rhythm and sleep-wake cycle. Effects of light c...

Ngày tải lên: 10/08/2014, 09:20

... fibroblast, kynurenine pathway, gene expression, cytokine Introduction The kynurenine pathway (KP) is the main route of tryp- tophan degradation in the human body and generates several neuroactive and ... 8:25 http://www.journal-inflammation.com/content/8/1/25 Page 7 of 7 RESEARCH Open Access Effects of pro -inflammatory cytokines on expression of kynurenine pathway en...

Ngày tải lên: 11/08/2014, 03:20

... abnormalities in the kynurenine pathway of tryptophan degradation. Keywords: human, fibroblast, kynurenine pathway, gene expression, cytokine Introduction The kynurenine pathway (KP) is the main route of ... first and rate-limiting step of this pathway and is highly induced by the pro-inflamma- tory cytokine interferon (IFN)-g [22,23]. However, it is not clear if pro -inf...

Ngày tải lên: 11/08/2014, 06:23

... above one’s usual activity, of moderate-intensity physical activity five to seven days a week by integrating short bouts of activity into the day, such as increasing the amount of walking, perform- ing ... provide education and to control for the effects of being enrolled in a clini- cal trial and receiving increased attention and social support. Moreover, by providing a m...

Ngày tải lên: 12/08/2014, 12:20

... proliferation and survival, was increased by various concentrations of CSC, and sustained up to 24 h only at mitogenic concentrations of CSC (1 AU/ml). Higher, cytotoxic concentrations of CSC resulted in ... pathogenesis of smoking -induced lung injury, and more specifically to the epithelial changes that may accompany COPD and chronic bronchitis. Our observation on...

Ngày tải lên: 12/08/2014, 18:20

... redox cycling and consequently quinone dependent production of reactive oxygen species. In rat and mouse, a wide range of chemicals including polyaromatic hydrocarbons, azo dyes and quinones induces ... activity, either due to knockout of the DTD gene or by dicoumarol enzyme inhibition, causes an increase in quinone dependent toxicity [12,35]. The cells inability to break...

Ngày tải lên: 13/08/2014, 13:20

... stimulation of tender points may activate sensitized polymodal-type receptors thereby relieving pain. In clinical practice, acupuncture treatment may be effective on myofascial pain syndromes. Barlas ... acupuncture largely depends on the choice and number of acupoints. Recent clinical investigations on musculoskeletal pain, such as myofascial pain syndrome and fibromyalgesi...

Ngày tải lên: 13/08/2014, 15:21