Báo cáo y học: "High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts" doc
Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx
... Kokkola R, Zhang M, Yang H, Tracey KJ: High mobility group 1 protein (HMG -1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 2000, 19 2:565-570. 14 . Rouhiainen A, Imai ... enzyme-linked immunosorbent assay; ELISPOT = enzyme-linked immunosorbent spot; HMG = high -mobility group; HMGB1 = high -mobility group box protein 1; IFN = interferon; IL...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts" doc
... (ng/ml) + + + + + + + + + + + + + + + + 1 10 10 0 1 10 10 0 1 10 10 0 1 10 10 0 1 10 10 0 1 10 10 0 1 10 10 0 1 10 10 0 IL -10 IL -1 β IL-8IL-6 ** ** ** ** 0 2 4 6 8 10 (ng/ml) - + - - - + + + - - 1 10 10 0 1 10 10 0 HMGB1 (4 μg/ml) LPS ... cytokine production induced by HMGB1 in complex with IL-1a or IL-1b we utilised IL-1RA, Anakinra. RASFs and OASF...
Ngày tải lên: 12/08/2014, 17:22
Báo cáo y học: "High mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis" potx
... TNF, interleukin (IL)-1a and -1b, IL6 and macrophage inflam- matory protein 1 (MIP1) [10 ,14 ,16 ]. During the inflam- matory process, HMGB1 mig ration to organs/tissue sites induces variou s inflammatory ... inflammatory c ytokines including TNF-a,IL-1a,IL-1b, IL-1RA, IL-6, IL-8, MIP-1a and MIP-1b, thereby promoting chronic inflammation [17 ,18 ]. HMGB1 has been su ggested to serve...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: "High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis." ppsx
... either neutralizing HMGB1 antigen-affinity purified polyclonal anti- bodies or the anti -inflammatory domain of HMGB1, termed the A -box protein, significantly reduced mean arthritis scores, disease-induced weight ... Sloan RP, Sama AE, Tracey KJ: Cholin- ergic anti -inflammatory pathway activity and high mobility group box- 1 (HMGB1) serum levels in patients with rheuma- toi...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "High mobility group box-1 protein - one step closer to the clinic" docx
... disease and cancer. Recently, a causal role for HMGB1 in acute myocardial infarction injury in mice was documented [15 ]. Interestingly, HMGB1 appeared as soon as 30 minutes after myocardial injury, ... HMGB1 polymorphisms with outcome in patients with systemic inflammatory response syndrome. Crit Care 2008, 12 :R83. 2. Goodwin GH, Sanders C, Johns EW: A new group of chro- mati...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo khoa học: "High mobility group box-1 protein in patients with suspected community-acquired infections and sepsis: a prospective study" pot
... SD Charlson Index 1. 6 ± 1. 3 1. 3 ± 1. 3 1. 1 ± 1. 3 1. 2 ± 1. 3 Laboratory findings, mean ± SD Haemoglobin, mmol/l 8 .1 ± 1. 1 8.2 ± 1. 2 8.2 ± 1. 2 8.2 ± 1. 1 Platelet count, 10 9 /l 288.5 ± 10 8.2 324.5 ± 210 .6 ... strategies for diagnosis and therapy. High mobility group box- 1 protein (HMGB1) has been known for many years as a nuclear chromosomal protein. Its...
Ngày tải lên: 13/08/2014, 03:20
Báo cáo y học: "Unraveling the role of high mobility group box protein 1 in severe traum" doc
... highly purified eukaryotic recombinant HMGB1 (amphoterin). J Leukoc Biol 2007, 81: 49-58. 9. Sha Y, Zmijewski J, Xu Z, Abraham E: HMGB1 develops enhanced proinflammatory activity by binding to cytokines. ... of HMGB1 on organ function, it would now appear that anti- HMGB1 therapies owe their efficacy to diminishing the adjuvant role of HMGB1 in potentiating inflammatory res- ponses throu...
Ngày tải lên: 13/08/2014, 19:20
Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life" pdf
... H: Interleukin-6 levels in syn- ovial fluids of patients with rheumatoid arthritis correlated with the infiltration of inflammatory cells in synovial membrane. Rheumatol Int 2006, 26 :10 96 -11 00. 25. ... knee pain [11 ] and joint replacement with more than 10 % lost before any radiological changes can be detected [12 ]. As the knee is one of the most common joints to be affec...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " Human Polycomb group EED protein negatively affects HIV-1 assembly and release" pot
... 5 10 15 20 0 w/o EED with EED 1. 25 1. 20 1. 15 1. 10 1. 05 density 5 10 15 20 0 5 10 15 20 with EED w/o EED Gradient fractions 0 5 10 15 20 CAp24, pg /ml (x100) 20 w/o EED with EED 15 10 0 1. 25 1. 20 1. 15 1. 10 1. 05 density (d) (f) Gradient ... pg/ml (x100) 1 5 10 15 20 25 20 15 10 5 density 1. 25 1. 20 1. 15 1. 10 1. 05 w/o EED + WTNef with EED +...
Ngày tải lên: 13/08/2014, 05:22
Báo cáo y học: "High levels of circulating leukocyte microparticles are associated with better outcome in acute respiratory distress syndrome" pdf
... to multi-organ dys- function. A balance between pro -inflammatory and anti- inflammatory effects is observed in the course of acute lung injury. Sustained high levels of pro -inflammatory Figure ... and stored at -80°C until analysis. Cytometry analysis Antibodies anti-CD 41- FITC (clone PL2-49) and IgG1- FITC (clone 2H 11/ 2H12) were from BioCytex (Mar- seille, France). Antibodies anti...
Ngày tải lên: 14/08/2014, 07:21