... TNF,interleukin (IL)-1a and -1b, IL6 and macrophage inflam-matory protein 1 (MIP1) [10 ,14 ,16 ]. During the inflam-matory process, HMGB1 mig ration to organs/tissuesites induces variou s inflammatory ... inflammatory c ytokines includingTNF-a,IL-1a,IL-1b, IL-1RA, IL-6, IL-8, MIP-1a andMIP-1b, thereby promoting chronic inflammation [17 ,18 ]. HMGB1 has been su ggested to serve as a pro- inflammatory cytokine ... HMGB -1: High Mobility Group Box Protein- 1 Figure 1 High Mobility Group Box Protein- 1 (HMGB -1) bycategory of groups.Figure 2 Receiver operating characteristic (ROC) curve of Hig h Mobility Group...