Báo cáo y học: "The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration" ppt
Báo cáo y học: "The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration" ppt
... ChangesinDNA,proteoglycan(sulfated glycosaminoglycan) and hyaluronic acid content. Changes in DNA, proteoglycan (sulfated glycosaminoglycan (GAG)) and hyaluronic acid (HA) contents of the annulus ... significance. Link N did not alter the DNA content of the discs. Link N injection led to a significant increase in aggrecan gene expression and a significant decrease in pro...
Ngày tải lên: 12/08/2014, 17:22
Báo cáo y học: "The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis" doc
... (TNF)-α and IL-1 has been validated in preclinical animal models and in humans [1,2]. Current therapy targeting IL-1 in RA is based on a recombinant form of the IL-1 receptor antagonist (IL-1Ra; anakinra), ... ACZ885, a fully human monoclonal antibody that neutralizes the bioactivity of human IL-1β, was generated to study the potent and long-lasting neutralization of IL-1β in...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " Systemic Epstein-Barr-virus-positive T cell lymphoproliferative childhood disease in a 22-year-old Caucasian man: A case report and review of the literature" docx
... cell lymphoproliferative childhood disease in a 22-year-old Caucasian man: A case report and review of the literature Valentina Tabanelli 1 , Claudio Agostinelli 1 , Elena Sabattini 1 , Anna Gazzola 1 , ... research, analyzed data and wrote the manuscript; CA performed research and analyzed data; ES and FB analyzed data; SC and GM were responsible for patient care and provided clinica...
Ngày tải lên: 10/08/2014, 23:21
Báo cáo y học: "Rare association between cystic fibrosis, Chiari I malformation, and hydrocephalus in a baby: a case report and review of the literature" potx
... long-term clinical outcome remains to be determined. Consent Written informed consent was obtained from the patient’s next -of- kin for publication of this case report and any accompanying images. ... production of this manuscript. Authors’ contributions AJP and VHR were major contributors in the writing and editing of the manuscript. AJ was a major contributor in the interpretati...
Ngày tải lên: 10/08/2014, 23:22
Báo cáo y học: "The self-organizing fractal theory as a universal discovery method: the phenomenon of life" pptx
... electron tunneling in both media had been experimentally demonstrated. Next, it was assumed that the rate of charge transfer in proteins and DNA decays exponentially with the linear distance separating ... individual components into a func- tional chain can shorten the waiting time even more. Finally, in analogy to the incessant synthesis/import and degradation/export of cellu- la...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo Y học: RING finger, B-box, and coiled-coil (RBCC) protein expression in branchial epithelial cells of Japanese eel, Anguilla japonica pot
... proteins are a group of zinc-binding proteins that belong to the RING finger family. They are so called because they have an N- terminal RING finger motif defined by one histidine and seven cysteine ... architecture and its maintenance by targeting, for degradation via the proteasomal pathway, a group of regulatory and structural proteins that are not necessary for adaptation to new osm...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo y học: "α Does protein kinase R mediate TNF-α- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism" pps
... and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism? Sophie J Gilbert, Victor C Duance and Deborah J Mason Connective ... dependent The amount of sGAG remaining within the cartilage explant after 24 hours of treatment with TNF-α and C 2 -ceramide in the presence and absence of 2-AP was determined...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study" docx
... replication sample 2, and again a significant association in replication sample 3 (European Caucasian families). Finally, significant RA associa- tion and linkage were observed when all sets were combined. The ... neither significant association nor linkage between SNP1 and RA in sample 1. For SNP2, we observed a significant association for the C allele and a strong trend for a RA...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "The paediatric flat foot proforma (p-FFP): improved and abridged following a reproducibility study" pptx
... bearing), range of motion (reduced, increased or asymmetry), tender areas (joint location and presentation eg swelling), gait (limp, asymmetry, or altered angle of gait; examined shod and barefoot), ... (Microsoft Inc, Redmond, Washington) software packages. To determine intra-rater agreement, intraclass correlation coefficients (ICCs) were calculated (model [3,1] based on two-way analys...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: "Early response predicts subsequent response to olanzapine long-acting injection in a randomized, double-blind clinical trial of treatment for schizophrenia" potx
... continue to accumulate, reaching steady state olanzapine plasma con- centrations approximately 3 months after initiation of therapy [10]. Given that olanzapine LAI takes longer to reach steady ... response to antipsychotic medication may serve as an early clinical marker that cli nicians can use when balancing the benefit and risk of treatment with olanzapine LAI for acutely ill patient...
Ngày tải lên: 11/08/2014, 15:22