Báo cáo y học: "Identification of target antigens of antiendothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach" potx

... duration less than 1 year. Patients were evaluated clinically and serologically, and radiographs were obtained at initial and 1-year visits. Sera were assayed for IgG- AGE and anti-IgG-AGE antibodies ... IgG-AGE and anti-IgG-AGE antibodies were present early in the course of RA and other inflammatory arthropathies. We prospectively followed a cohort of 238 patients...

Ngày tải lên: 09/08/2014, 01:21

... mobi- lity in polyacrylamide gel s [13]. H MGB1 is a cytokine that can be released by activated monocytes, macro- phages, n eutrophils and platelets, and in turn mediates inflammation and enhanced cell ... motility. Extracellular HMGB1 acts as a late mediator of inflammation. Tracey and collaborators detected HMGB1 in the serum of sep- tic patients [14] and found t...

Ngày tải lên: 13/08/2014, 23:20

... Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach. Arthritis Research & Therapy ... protein extracts: mitochondrial fumarate hydratase, lamin A/ C and vinculin. IgG reac- tivity against vinculin and lamin A/ C in sera from GCA...

Ngày tải lên: 12/08/2014, 17:22

... asso- ciated with the general suppression of activity of inflam- matory cells and relaxation of airway and vascular smooth muscle [17]. Levels of intracellular cAMP are determined by the enzymatic balance ... potent and broader anti-inflammatory effects against smoke-induced lung inflammation than roflumilast. Moreover, the protective effect of PDE4B/4D and 7A AON was...

Ngày tải lên: 12/08/2014, 14:20

... of anti-dsDNA antibodies and clinical manifestations is not required in SLE classification and diagnosis. For example, the previous presence of anti-dsDNA antibodies (by any assay) and accordingly a positive ... anti-dsDNA antibody-mediated injury. Anti-dsDNA antibodies and lupus pathophysiology Anti-dsDNA antibodies and SLE pathophysiology are currently quite loosel...

Ngày tải lên: 09/08/2014, 06:22

... TLR3 agonist, polyinosinic-polycytidylic acid (poly(I:C)), on the growth of human NB cells was evaluated by WST-1 cell proliferation assay, flow cytometry analysis, and immunoblot analysis. Blockade ... interferon alpha [38], simultaneous administration of CpG DNA [19,39], or targeting MYCN or MDA5 may be helpful in augmenting the poly(I:C) sensitivity and NB immunotherapy. As an...

Ngày tải lên: 10/08/2014, 10:20

... lowing the manufacturer’s standard protocol. The data were analyze d by a comparison with those of the 96 hapmap Asian individuals used as control. Initial analysis and quality assessment of ... the array data were performed with Genotyping Console (Affymetrix, CA, USA). The median absolute pair-wise difference (MAPD) of each chip was used as a quality assessment of the arra...

Ngày tải lên: 11/08/2014, 00:22

... Htun M, Win Maw T, Khin Khin A, San San O, et al.: Clinical trial of the intradermal administration of hepatitis B vaccine produced at the department of medical research, Myanmar. vaccine 2002, ... μg) of the vac- cine intradermally, plus 100 mg Levamisole per day for 12 day, from 6 days before of vaccination until 6 days after each vaccination. Demographic characteristics and th...

Ngày tải lên: 11/08/2014, 10:23

... by a quantitative sandwich ELISA developed specifically for the mouse (Quantikine #MLA00 and MRA00; R&D Sys- tems, Minneapolis, MN, USA). Intra-assay and inter- assay coefficients of variation ... analysis of the cartilage material property data. LAS contributed to the experimental design and analy- sis of the cartilage material property data, and participated in the int...

Ngày tải lên: 12/08/2014, 14:22

... reporting no pain increasing until week seven and remaining relatively steady after that; again with a small decline at the end of the period. In the first week, 16% reported severe pain, and that proportion ... approval. Clinical procedures Patients who agreed to participate had a standardised clinical examination. Based on the examination they were classified according to a...

Ngày tải lên: 13/08/2014, 14:20