Báo cáo y học: "Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an antiinflammatory cyclooxygenase-2 (COX-2) pathway" doc

... Casorati G, Parmiani G, Eshhar Z, Canevari S, Colombo MP: Targeting of interleukin 2 to human ovarian carcinoma by fusion with a single-chain Fv of antifolate receptor antibody. Cancer Res 1998, ... beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. Can...

Ngày tải lên: 12/08/2014, 15:22

... not known. Reichman and Mathews [33] analyzed the RNA binding properties of NF90 family of dsRNA binding proteins and suggest that the NF90ctv isoform (lacking the RGD and GQSY domains) has tenfold ... ribonucleoprotein (RNP) complexes formed Competition Analysis of RNA Binding SpecificityFigure 1 Competition Analysis of RNA Binding Specificity. A: The structure of the wild type TA...

Ngày tải lên: 13/08/2014, 05:22

... Access Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti- inflammatory cyclooxygenase-2 (COX-2) pathway Valentina Ulivi 1† , Manuela ... Biotechnology (Santa Cruz, CA, USA). Anti-actin antib ody was raised against a peptide mapping at the C-terminus of actin of human origin and was reacti...

Ngày tải lên: 12/08/2014, 17:21

... domain of human retinoblastoma pro- tein-binding zinc finger protein 1 (RIZ1). Int J Mol Sci 2008; 9: 943-50. 21. Chen L, Ling B, Alcorn J, Yang J. Analysis of the expression of human N-myristoyltransferase ... might play an important role in tumor metastasis, and the PR domain alone possessed anticancer activity. Key words: RIZ1, RIZ, Human tumor suppressor, tumor metast...

Ngày tải lên: 25/10/2012, 11:15

... analyzed by native-PAGE and immunoblot ana- lysis using SL12. (C) Proteins were produced by in vitro transcription/ translation using wheat germ extracts and cDNA encoding wild-type and the indicated ... systematic analysis of the role played by the two sets of Ser/Thr residues in the virus-dependent activation of IRF-3. To this end, we examined the phenotypes of a variety of...

Ngày tải lên: 17/03/2014, 10:20

... was measured in the presence of a molar excess of inhibitors from all four classes of proteases ) aprotinin, benzamidine, leupeptin, Soya bean t rypsin inhibitor (SBTI) 6,7 ,(1-trans- epoxysuccinyl-leucylamido ... Juliano 2 , Miche Á le Ferrer 1 , Thierry Moreau 1 and Francis Gauthier 1 1 Laboratory of Enzymology and Protein Chemistry, INSERM EMI-U 00-10, University FrancË ois Rabel...

Ngày tải lên: 24/03/2014, 00:21

... m M Br – and 2 m M H 2 O 2 on a Cary 50 [23]. The kinetic parameters were determined using the ENZYMEKINETICS program from Trinity Software. Assay of PhoN-Se brominating activity. The brominating activity ... likely that phosphate binds at the active site of the enzyme and prevents binding of the vanadate. Therefore phosphate should be absent in the assay. To induce the brominating...

Ngày tải lên: 24/03/2014, 03:21

... BLyS with high affinity. The antibody exerts its biologic activity by preventing the binding of BLyS to its receptors [19]. Belimumab potently inhibits BLyS-induced proliferation of B cells in ... neutrophil count; BlyS: B-lymphocyte stimulator; dsDNA: double-stranded DNA; ELISA: enzyme-linked immunosorbent assay; HAHA: human anti -human antibody; mAb: monoclonal antibody; PGA: Ph...

Ngày tải lên: 09/08/2014, 13:21

... on days 3, 7, 10, 14 and 17. Results Anti-HIV-1 activity and cytotoxicity of WR1065 in human TCBs In HIV-1-infected human TCBs, the HIV-1 titers, deter- mined in the absence of drug, ranged ... (non-apoptotic). Flow Cytometry for determination of cell cycle parameters in human TCBs cultured in the presence of WR1065 Flow cytometry was used to evaluate the integrity...

Ngày tải lên: 10/08/2014, 05:21

... destruction of human immunodeficiency virus in human serum by inhibiting the protective action of complement factor H and decay accelerating factor (DAF, CD55). The Journal of experimental medicine ... M, McNamara A, Lint TF, Landay AL, Spear GT: Complement and antibody mediate enhancement of HIV infection by increasing virus binding and provirus formation. AIDS (London, En...

Ngày tải lên: 10/08/2014, 05:21