Báo cáo sinh học: " Linear-time protein 3-D structure searching with insertions and deletions" ppsx

... Open Access Linear-time protein 3-D structure searching with insertions and deletions Tetsuo Shibuya 1* , Jesper Jansson 2 , Kunihiko Sadakane 3 Abstract Background: Two biomolecular 3-D structures ... reporting all substructures in a 3-D structure database of chain molecules (such as proteins) which are similar to a given query 3-D structure, with consideration of...

Ngày tải lên: 12/08/2014, 17:20

... Solitary 3-day-old ducklings used 38% less metabolic energy swimming in the decoy’s wake than when swimming without the wake (with the decoy suspended above the water surface). Further experiments with ... as baby monkeys could not keep up with their troop if their mothers did not carry them, dolphin calves might be unable to keep up with the adults if they did not keep close to their...

Ngày tải lên: 06/08/2014, 18:21

... size Explicit- and implicit tabu structuresFigure 4 Explicit- and implicit tabu structures. Black points represent explicit tabu structures and red points represent implicit tabu structures. Algorithm ... vector as the native structure is found (but not necessarily identical struc- tures). To evaluate the quality of the structures with low energy, the RMSD with the native struct...

Ngày tải lên: 12/08/2014, 17:20

... 3.1 and Corollary 3.4,andin Proposition 2.4 and Corollary 3.3, we get the transformations between the functionals F T and F,andF T and F J . Proposition 3.6 Quadratic functionals for T and ... systems S with B k being invertible, utilizing the transformations in Propositions 2.8 and 2.9 for the passage between equation J and system S and the transformations in The...

Ngày tải lên: 21/06/2014, 16:20

... residue and the gold. ((bb)) FRET analysis of STM pep2 , STM pep9 and STM in solution on exposure to CDK2, CDK4 and CDK-free lysate. The peptide aptamers and lysate proteins were tagged with Alexa ... a number of different ligands, and hence lack specificity [7]. Alternative probe molecules, for example DNA and RNA aptamers [8-11], have been used in protein arrays, and alth...

Ngày tải lên: 06/08/2014, 18:21

... Note th at these scores (and hence the candidate i’) depend only on i, j’,andd j’,j and are independent of d i,i’ and j. The following lemma shows that the notion of a candidate given in Def. 1 ... notion of a candidate such that it is not necessary to minimize over all possible i’ and j’ but only over the candidates. Definition 1 (R&G candidate) Let iji i< ′ < ′ < ′ 12 a...

Ngày tải lên: 12/08/2014, 17:20

... replicates where both STRUCTURE and BAPS failed to estimate the correct number of clusters in scenario 3 with s = 0.7 and scenario 6 with m = 0.01 were randomised to re-establish HWE and/ or LE. This ... population structure and the relationship with geographic regions in humansFigure 4 Schematic representation of the population structure and the relationship with geogr...

Ngày tải lên: 14/08/2014, 13:21

... multiple entry and exit training system that matches and adapts training to the prevailing population and service needs and demands, while lifting overall standards over time and highlighting ... compe- tencies and training should reduce such conflicts and increase interprofessional respect. The difference between demand and supply is so large in most developing coun- tries th...

Ngày tải lên: 18/06/2014, 17:20

... purposes) and interacts with its immediate neighbours and the sys- tem as a whole. The inclusion of feedback and temporal features makes the model dynamic and non-linear rather than static and linear. Testing ... overall system structure and tested for both its local and global effects. While spreadsheets show the results of calculations, drilling down to the assumptions an...

Ngày tải lên: 18/06/2014, 17:20

... advantaged and disadvantaged – input and buy-in were crucial for success (community effectiveness) [15]. Develop learning methods, materials and approaches With an appropriate planning authority and ... curricula and estab- lish national standards. Walker advises that this group should include representatives from local and national training institutions in addition to external...

Ngày tải lên: 18/06/2014, 17:20