Báo cáo sinh học: "HuMiTar: A sequence-based method for prediction of human microRNA targets" ppt

... motifs in human promoters and 3'UTRs by comparison of several mammals. Nature 2005, 434:338-345. 14. Watanabe Y, Yachie N, Numata K, Saito R, Kanai A, Tomita M: Com- putational analysis of microRNA ... we also estimate the computational complexity of the pro- posed method. Table 1: Datasets. Dataset name Dataset details Dataset goal Design set 66 human miR-mRNA duplexes pu...

Ngày tải lên: 12/08/2014, 17:20

... have reached the point of clinical trial [8,9]. The availability of molecular genetic technology has opened up a large range of potential strategies for the treatment of leukemia. Hematological ... malignancies have several features that make them particularly amenable to gene transfer approaches. The neoplastic cells circulate in the blood, so that large numbers of tumor cells...

Ngày tải lên: 14/08/2014, 19:22

... D, Gautam B, Hassanali M: DDrruuggBBaannkk:: aa kknnoowwlleeddggeebbaassee ooff ddrruuggss,, ddrruugg aaccttiioonnss aanndd ddrruugg ttaarrggeettss Nucleic Acids Res 2008, 3366((DDaattaabbaassee iissssuuee)):: D901-D906. 27. ... atropine, ophenadrine and procaine as members of this category. The network approach not only gives us a systematic way to organize our vast databases, but als...

Ngày tải lên: 06/08/2014, 18:21

... Rica Isol SAN 13 L. santarosai Tarassovi* Rama* Isolate 3 Costa Rica Isol SAN 14 L. santarosai Tarassovi* Rama* Isolate 5 Costa Rica Isol SAN 15 L. santarosai Bataviae* Claytoni* Isolate 6 Costa ... santarosai Pyrogenes Varela 1019 Nicaragua RB3 SAN 05 L. santarosai Grippotyphosa Canalzonae CZ188 Panama RK3 SAN 06 L. santarosai Bataviae* Brasiliensis* An 776 Brazil Isol SAN 07 L. santarosai S...

Ngày tải lên: 08/08/2014, 19:20

... [49]. Additional material Abbreviations AAPD: average antisense product displacement; miRNA/miR: microRNA; miR- TRAP: miRNA Tests for Read Analysis and Prediction; moR: microRNA- offset- RNA; piRNA: ... S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mat...

Ngày tải lên: 09/08/2014, 20:21

... paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), ... graphical user interface but can be s et in the command-line version of Jane. Values of the se parameters were systematically evaluated and the best values found are used as def...

Ngày tải lên: 12/08/2014, 17:20

... interaction assays. For these gold standard pairs, we fixed the value of the 'actual interaction' variable accordingly. In all other protein pairs, we leave the actual interaction variables as ... co-expression and GO distance, which are noisy sensors for the actual interaction variable T ij .I. Note that an actual interaction variable may have several observa- tion variables...

Ngày tải lên: 14/08/2014, 08:20

... Members of this fam- ily are typically oxidases that are capable of performing a wide range of substrate (e.g. sugars and alcohols) oxidation reactions [48]. The flavogenome of the model plant A. thaliana ... range of biochemical transformations necessary for all aspects of life. Some of these cofactors, such as vitamin B 12 and vitamin H (biotin), catalyze a small but nev...

Ngày tải lên: 28/03/2014, 22:21

... for return of medical service in underserved areas: a health worker enters into a contract to practise for a number of years in an underserved area in exchange for a financial payoff. Table 1 shows ... the rural Australian medical undergraduate scholarship 'rural background' criterion. Australian Journal of Rural Health 2005, 13:137-141. 73. Albrecht Z, Ziderman...

Ngày tải lên: 18/06/2014, 17:20

... 5'- CAGCTCCAGGGGGGGGGCGTCGCCGGGGTTC-3' (R for C18 5A) , 5'-GTGCCCCTGGACATCGCCACCAGCATC TGCAAG-3' (F for C22 5A) , 5'-CTTGCAGATGCTGGTGGC GATGTCCAGGGGCAC-3' (R for C22 5A) , 5'-ACCAG- CATCGCCAAGTACCCCGACTACATC-3' ... 5'-ACCAG- CATCGCCAAGTACCCCGACTACATC-3' (F for C22 9A) , 5'-ATGTAGTCGGGGTACTTGGCGATGCTGGTGCAGAT G-3' (R for C22...

Ngày tải lên: 18/06/2014, 18:20