Báo cáo y học: " Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells" pps

... release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells Aruna Kode, Se-Ran Yang and Irfan Rahman* Address: Department of Environmental Medicine, ... Central Page 1 of 3 (page number not for citation purposes) Respiratory Research Open Access Correction Differential effects of cigarette smoke on...

Ngày tải lên: 12/08/2014, 15:21

... Research Open Access Research Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar ... in primary human small air-way epithelial cellsFigure 1 Cigarette smoke extract differentially caused cytotoxicity in...

Ngày tải lên: 12/08/2014, 16:20

... smoking the damaging and irritating effects may prevail, giving rise to more pro- nounced inflammation. Studying the acute effects of smoking in intermittent healthy smokers has both advantages and ... It would be interesting to study the acute effects of smoking on lung tissue. Finally, CO in cigarette smoke may have dampened the inflammatory response, especially in...

Ngày tải lên: 12/08/2014, 18:21

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Ngày tải lên: 07/08/2014, 18:21

... Institutes of Health and the American Physio- logical Society for the care and use of laboratory animals. Animal model The ovine model of ALI and sepsis induced by smoke inhalation and instillation of ... with an early and transient increase in eNOS and an early and profound increase in iNOS expression, while expression of nNOS remained unchanged. Both 3-NT, a...

Ngày tải lên: 13/08/2014, 21:20

... doi:10.1046/j.1432-1033.2002.03070.x AA-CoA synthetase, inhibition of CoA-IT results in an increase in free AA and a corresponding build-up of AA in triacylglycerols that can be prevented by co-incubation of cells with CoA-synthetase ... incorporated into cellular glycerophospholipids by a distinct pathway. Free AA is initially converted to AA-CoA by AA-CoA synthe- tase (a...

Ngày tải lên: 22/02/2014, 07:20

... mechanical hyperalgesia in the acute phase of AIA. By contrast, repeated systemic application of sgp130 after onset of AIA only slightly attenuated pain at a late stage of AIA. None of the treatments ... sgp130. Conclusions: In addition to its role in chronic inflammation, IL-6 in the joint plays a significant role in the generation and maintenance of arthritic joi...

Ngày tải lên: 12/08/2014, 14:22

... PKR activation in primary human monocytes and macrophages. As an anti-inflammatory cytokine, over-expression of IL-10 may contribute to mycobacterial evasion of the host immunity. Radix Paeoniae ... Methods Plant material Radix Paeoniae Rubra was obtained from PuraPharm International Ltd. (Hong Kong, China). The raw mate- rial of the herb was authenticated by PuraPharm Corporat...

Ngày tải lên: 13/08/2014, 14:20

... 7. At pH 7.5 (Fig. 7A) , the majority of the PLB are in the form of highly ordered paracrystalline arrays based on networks of interconnected tubular tetrapodal membrane units forming a bicontinuous ... organization of prolamellar bodies of maize ( Zea mays ) Eva Selstam 1 , Jenny Schelin 1 , Tony Brain 2 and W. Patrick Williams 2 1 Umea ˚ Plant Science Center, Department o...

Ngày tải lên: 22/02/2014, 04:20

... formation of a pannus, which leads to swollen joints and finally to joint destruction. Inflammatory cells such as monocytes and neutrophils, together with T and B cells, infiltrate the synovial ... were tested in duplicate and values were compared with a standard curve. Transmigration assay Cell migration was examined in Transwell™ inserts (Corning Costar) with a diamet...

Ngày tải lên: 09/08/2014, 06:23